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Vision-language foundation models have shown great promise in computational pathology but remain primarily data-driven, lacking explicit integration of medical knowledge. We introduce KEEP (KnowledgE-Enhanced Pathology), a foundation model…

Image and Video Processing · Electrical Eng. & Systems 2026-01-28 Xiao Zhou , Luoyi Sun , Dexuan He , Wenbin Guan , Ge Wang , Ruifen Wang , Lifeng Wang , Xiaojun Yuan , Xin Sun , Ya Zhang , Kun Sun , Yanfeng Wang , Weidi Xie

Federated Learning (FL) enables multiple institutes to train models collaboratively without sharing private data. Current FL research focuses on communication efficiency, privacy protection, and personalization and assumes that the data of…

Computer Vision and Pattern Recognition · Computer Science 2024-06-18 Zhipeng Deng , Yuqiao Yang , Kenji Suzuki

Recent advances in microscopy have enabled the rapid generation of terabytes of image data in cell biology and biomedical research. Vision-language models (VLMs) offer a promising solution for large-scale biological image analysis,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-03 Alejandro Lozano , Jeffrey Nirschl , James Burgess , Sanket Rajan Gupte , Yuhui Zhang , Alyssa Unell , Serena Yeung-Levy

Federated learning (FL) enables collaborative learning of a deep learning model without sharing the data of participating sites. FL in medical image analysis tasks is relatively new and open for enhancements. In this study, we propose…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Gozde N. Gunesli , Mohsin Bilal , Shan E Ahmed Raza , Nasir M. Rajpoot

Despite the promise of foundation models in medical AI, current systems remain limited - they are modality-specific and lack transparent reasoning processes, hindering clinical adoption. To address this gap, we present EVLF-FM, a multimodal…

Anatomical understanding through deep learning is critical for automatic report generation, intra-operative navigation, and organ localization in medical imaging; however, its progress is constrained by the scarcity of expert-labeled data.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-29 Yiwei Li , Yikang Liu , Jiaqi Guo , Lin Zhao , Zheyuan Zhang , Xiao Chen , Boris Mailhe , Ankush Mukherjee , Terrence Chen , Shanhui Sun

We propose a margin-based loss for tuning joint vision-language models so that their gradient-based explanations are consistent with region-level annotations provided by humans for relatively smaller grounding datasets. We refer to this…

Computer Vision and Pattern Recognition · Computer Science 2024-01-09 Ziyan Yang , Kushal Kafle , Franck Dernoncourt , Vicente Ordonez

Clinical oncology generates vast, unstructured data that often contain inconsistencies, missing information, and ambiguities, making it difficult to extract reliable insights for data-driven decision-making. General-purpose large language…

Computation and Language · Computer Science 2025-03-12 Morteza Rohanian , Tarun Mehra , Nicola Miglino , Farhad Nooralahzadeh , Michael Krauthammer , Andreas Wicki

Histopathological images contain abundant phenotypic information and pathological patterns, which are the gold standards for disease diagnosis and essential for the prediction of patient prognosis and treatment outcome. In recent years,…

Computer Vision and Pattern Recognition · Computer Science 2022-10-26 Linhao Qu , Siyu Liu , Xiaoyu Liu , Manning Wang , Zhijian Song

We propose a deep learning based method for classification of commonly occurring pathologies in chest X-ray images. The vast number of publicly available chest X-ray images provides the data necessary for successfully employing deep…

Image and Video Processing · Electrical Eng. & Systems 2020-06-24 Mohammad S. Majdi , Khalil N. Salman , Michael F. Morris , Nirav C. Merchant , Jeffrey J. Rodriguez

Deep learning models have revolutionized medical imaging and diagnostics, yet their opaque nature poses challenges for clinical adoption and trust. Amongst approaches to improve model interpretability, concept-based explanations aim to…

Computer Vision and Pattern Recognition · Computer Science 2024-10-24 Vijay Sadashivaiah , Pingkun Yan , James A. Hendler

In chest X-ray (CXR) image analysis, rule-based systems are usually employed to extract labels from reports for dataset releases. However, there is still room for improvement in label quality. These labelers typically output only presence…

Image and Video Processing · Electrical Eng. & Systems 2025-06-03 Ricardo Bigolin Lanfredi , Pritam Mukherjee , Ronald Summers

Recent learning-based approaches have achieved impressive results in the field of single-shot camera localization. However, how best to fuse multiple modalities (e.g., image and depth) and to deal with degraded or missing input are less…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Kaichen Zhou , Changhao Chen , Bing Wang , Muhamad Risqi U. Saputra , Niki Trigoni , Andrew Markham

To enable a deep learning-based system to be used in the medical domain as a computer-aided diagnosis system, it is essential to not only classify diseases but also present the locations of the diseases. However, collecting instance-level…

Computer Vision and Pattern Recognition · Computer Science 2021-01-26 Hyun-Woo Kim , Hong-Gyu Jung , Seong-Whan Lee

Digital pathology tasks have benefited greatly from modern deep learning algorithms. However, their need for large quantities of annotated data has been identified as a key challenge. This need for data can be countered by using…

Computer Vision and Pattern Recognition · Computer Science 2021-05-13 Jacob Carse , Frank Carey , Stephen McKenna

Integrating functional magnetic resonance imaging (fMRI) connectivity data with phenotypic textual descriptors (e.g., disease label, demographic data) holds significant potential to advance our understanding of neurological conditions.…

Machine Learning · Computer Science 2025-03-31 Yanting Yang , Xiaoxiao Li

The success of CLIP-like vision-language models (VLMs) on natural images has inspired medical counterparts, yet existing approaches largely fall into two extremes: specialist models trained on single-domain data, which capture…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 M. Arda Aydın , Melih B. Yilmaz , Aykut Koç , Tolga Çukur

Accurate endoscopic image segmentation on the polyps is critical for early colorectal cancer detection. However, this task remains challenging due to low contrast with surrounding mucosa, specular highlights, and indistinct boundaries. To…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Juntong Fan , Shuyi Fan , Debesh Jha , Changsheng Fang , Tieyong Zeng , Hengyong Yu , Dayang Wang

Artificial intelligence (AI)-enabled diagnostics in maxillofacial pathology require structured, high-quality multimodal datasets. However, existing resources provide limited ameloblastoma coverage and lack the format consistency needed for…

Artificial Intelligence · Computer Science 2026-02-06 Ajo Babu George , Anna Mariam John , Athul Anoop , Balu Bhasuran

Extracting, harvesting and building large-scale annotated radiological image datasets is a greatly important yet challenging problem. It is also the bottleneck to designing more effective data-hungry computing paradigms (e.g., deep…

Computer Vision and Pattern Recognition · Computer Science 2017-10-11 Ke Yan , Xiaosong Wang , Le Lu , Ronald M. Summers