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In-context learning (ICL), teaching a large language model (LLM) to perform a task with few-shot demonstrations rather than adjusting the model parameters, has emerged as a strong paradigm for using LLMs. While early studies primarily used…

Computation and Language · Computer Science 2023-05-24 Man Luo , Xin Xu , Zhuyun Dai , Panupong Pasupat , Mehran Kazemi , Chitta Baral , Vaiva Imbrasaite , Vincent Y Zhao

Large Language Models (LLMs) are increasingly deployed in healthcare, yet their communicative alignment with clinical standards remains insufficiently quantified. We conduct a multidimensional evaluation of general-purpose and…

Computation and Language · Computer Science 2026-04-23 Mariano Barone , Francesco Di Serio , Roberto Moio , Marco Postiglione , Giuseppe Riccio , Antonio Romano , Vincenzo Moscato

Several recent works seek to develop foundation models specifically for medical applications, adapting general-purpose large language models (LLMs) and vision-language models (VLMs) via continued pretraining on publicly available biomedical…

Computation and Language · Computer Science 2024-11-21 Daniel P. Jeong , Saurabh Garg , Zachary C. Lipton , Michael Oberst

There is vivid research on adapting Large Language Models (LLMs) to perform a variety of tasks in high-stakes domains such as healthcare. Despite their popularity, there is a lack of understanding of the extent and contributing factors that…

Computation and Language · Computer Science 2024-06-07 Anand Subramanian , Viktor Schlegel , Abhinav Ramesh Kashyap , Thanh-Tung Nguyen , Vijay Prakash Dwivedi , Stefan Winkler

In this paper, we investigate Extractive Question Answering (EQA) with Large Language Models (LLMs) under domain drift, i.e., can LLMs generalize to domains that require specific knowledge such as medicine and law in a zero-shot fashion…

Computation and Language · Computer Science 2024-12-13 Saptarshi Sengupta , Wenpeng Yin , Preslav Nakov , Shreya Ghosh , Suhang Wang

Large Language Models (LLMs), being generic task solvers, are versatile. However, despite the vast amount of data they are trained on, there are speculations about their adaptation capabilities to a new domain. Additionally, the simple…

Computation and Language · Computer Science 2025-09-03 Anum Afzal , Mehul Kumawat , Florian Matthes

The advancement of large language models (LLMs) has opened new frontiers in natural language processing, particularly in specialized domains like healthcare. In this paper, we propose the Incremental Curriculum-Based Fine-Tuning (ICFT)…

Computation and Language · Computer Science 2025-02-04 Robert Long , Eric Gonzalez , Harrison Fuller

This paper examines the comparative effectiveness of a specialized compiled language model and a general-purpose model like OpenAI's GPT-3.5 in detecting SDGs within text data. It presents a critical review of Large Language Models (LLMs),…

Computation and Language · Computer Science 2023-07-31 Arash Hajikhani , Carolyn Cole

Lexical normalisation (LN) is the process of correcting each word in a dataset to its canonical form so that it may be more easily and more accurately analysed. Most lexical normalisation systems operate at the character-level, while…

Computation and Language · Computer Science 2019-11-15 Michael Stewart , Wei Liu , Rachel Cardell-Oliver

Inevitable domain and task discrepancies in real-world scenarios can impair the generalization performance of the pre-trained deep models for medical data. Therefore, we audaciously propose that we should build a general-purpose medical AI…

Computer Vision and Pattern Recognition · Computer Science 2023-03-14 Huahui Yi , Ziyuan Qin , Qicheng Lao , Wei Xu , Zekun Jiang , Dequan Wang , Shaoting Zhang , Kang Li

Large language models (LLMs) are becoming increasingly relevant as a potential tool for healthcare, aiding communication between clinicians, researchers, and patients. However, traditional evaluations of LLMs on medical exam questions do…

Computation and Language · Computer Science 2023-09-19 Rojin Ziaei , Samuel Schmidgall

This study aims to guide language model selection by investigating: 1) the necessity of finetuning versus zero-shot usage, 2) the benefits of domain-adjacent versus generic pretrained models, 3) the value of further domain-specific…

Computation and Language · Computer Science 2025-09-25 Lovedeep Gondara , Jonathan Simkin , Graham Sayle , Shebnum Devji , Gregory Arbour , Raymond Ng

Language models are typically evaluated on their success at predicting the distribution of specific words in specific contexts. Yet linguistic knowledge also encodes relationships between contexts, allowing inferences between word…

Computation and Language · Computer Science 2023-11-09 Michael Wilson , Jackson Petty , Robert Frank

Large language models with a transformer-based encoder/decoder architecture, such as T5, have become standard platforms for supervised tasks. To bring these technologies to the clinical domain, recent work has trained new or adapted…

Computation and Language · Computer Science 2024-12-10 Yahan Li , Keith Harrigian , Ayah Zirikly , Mark Dredze

The integration of Large Language Models (LLMs) into medical applications has sparked widespread interest across the healthcare industry, from drug discovery and development to clinical decision support, assisting telemedicine, medical…

Computation and Language · Computer Science 2024-12-03 Zifeng Wang , Hanyin Wang , Benjamin Danek , Ying Li , Christina Mack , Hoifung Poon , Yajuan Wang , Pranav Rajpurkar , Jimeng Sun

Clinical problem-solving requires processing of semantic medical knowledge such as illness scripts and numerical medical knowledge of diagnostic tests for evidence-based decision-making. As large language models (LLMs) show promising…

Large language models (LLMs) are incredible and versatile tools for text-based tasks that have enabled countless, previously unimaginable, applications. Retrieval models, in contrast, have not yet seen such capable general-purpose models…

Information Retrieval · Computer Science 2025-09-10 Julian Killingback , Hamed Zamani

The adoption of large language models (LLMs) to assist clinicians has attracted remarkable attention. Existing works mainly adopt the close-ended question-answering (QA) task with answer options for evaluation. However, many clinical…

General purpose language models (LMs) encounter difficulties when processing domain-specific jargon and terminology, which are frequently utilized in specialized fields such as medicine or industrial settings. Moreover, they often find it…

Computation and Language · Computer Science 2023-11-02 Daniel Eitan , Menachem Pirchi , Neta Glazer , Shai Meital , Gil Ayach , Gidon Krendel , Aviv Shamsian , Aviv Navon , Gil Hetz , Joseph Keshet

Large Language Models (LLMs) have revolutionized various sectors, including healthcare where they are employed in diverse applications. Their utility is particularly significant in the context of rare diseases, where data scarcity,…

Computation and Language · Computer Science 2024-08-20 Qiuhao Lu , Rui Li , Andrew Wen , Jinlian Wang , Liwei Wang , Hongfang Liu