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Tiered graph autoencoders provide the architecture and mechanisms for learning tiered latent representations and latent spaces for molecular graphs that explicitly represent and utilize groups (e.g., functional groups). This enables the…

Machine Learning · Computer Science 2021-07-02 Daniel T. Chang

Finding the biomarkers associated with ASD is helpful for understanding the underlying roots of the disorder and can lead to earlier diagnosis and more targeted treatment. A promising approach to identify biomarkers is using Graph Neural…

Machine Learning · Computer Science 2019-07-15 Xiaoxiao Li , Nicha C. Dvornek , Yuan Zhou , Juntang Zhuang , Pamela Ventola , James S. Duncan

Graph Learning (GL) is at the core of inference and analysis of connections in data mining and machine learning (ML). By observing a dataset of graph signals, and considering specific assumptions, Graph Signal Processing (GSP) tools can…

Machine Learning · Computer Science 2022-11-08 Aref Einizade , Sepideh Hajipour Sardouie

Despite the vast amount of information encoded in Knowledge Graphs (KGs), information about the class affiliation of entities remains often incomplete. Graph Convolutional Networks (GCNs) have been shown to be effective predictors of…

Artificial Intelligence · Computer Science 2024-12-30 Johannes Mäkelburg , Yiwen Peng , Mehwish Alam , Tobias Weller , Maribel Acosta

Convolutional neural networks have become state-of-the-art in a wide range of image recognition tasks. The interpretation of their predictions, however, is an active area of research. Whereas various interpretation methods have been…

Computer Vision and Pattern Recognition · Computer Science 2022-11-22 Kira Vinogradova , Alexandr Dibrov , Gene Myers

Predicting the response of a cancer cell line to a therapeutic drug is pivotal for personalized medicine. Despite numerous deep learning methods that have been developed for drug response prediction, integrating diverse information about…

Machine Learning · Computer Science 2025-03-31 Haoyuan Shi , Tao Xu , Xiaodi Li , Qian Gao , Zhiwei Xiong , Junfeng Xia , Zhenyu Yue

Deep learning methods for classifying medical images have demonstrated impressive accuracy in a wide range of tasks but often these models are hard to interpret, limiting their applicability in clinical practice. In this work we introduce a…

Image and Video Processing · Electrical Eng. & Systems 2019-08-13 James R. Clough , Ilkay Oksuz , Esther Puyol-Anton , Bram Ruijsink , Andrew P. King , Julia A. Schnabel

Retinal imaging provides a non-invasive window into systemic microvascular health and has emerged as a potential biomarker for systemic diseases. However, whether retinal features encode biologically meaningful systemic signals that can be…

Image and Video Processing · Electrical Eng. & Systems 2026-05-26 Mini Han Wang , Liting Huang , Wei Hong , Boonthawan Wingwon

Grid cells in the medial entorhinal cortex (MEC) of the mammalian brain exhibit a strikingly regular hexagonal firing field over space. These cells are learned after birth and are thought to support spatial navigation but also more abstract…

Neurons and Cognition · Quantitative Biology 2024-10-07 Mufeng Tang , Helen Barron , Rafal Bogacz

Image-based sequencing of mRNA makes it possible to see where in a tissue sample a given gene is active, and thus discern large numbers of different cell types in parallel. This is crucial for gaining a better understanding of tissue…

Quantitative Methods · Quantitative Biology 2018-02-27 Gabriele Partel , Giorgia Milli , Carolina Wählby

Accurate prediction of future blood glucose (BG) levels can effectively improve BG management for people living with diabetes, thereby reducing complications and improving quality of life. The state of the art of BG prediction has been…

Machine Learning · Computer Science 2024-02-27 Chengzhe Piao , Taiyu Zhu , Stephanie E Baldeweg , Paul Taylor , Pantelis Georgiou , Jiahao Sun , Jun Wang , Kezhi Li

Graph Neural Networks (GNNs) are a predominant method for graph representation learning. However, beyond subgraph frequency estimation, their application to network motif significance-profile (SP) prediction remains under-explored, with no…

Machine Learning · Computer Science 2025-07-11 Pedro C. Vieira , Miguel E. P. Silva , Pedro Manuel Pinto Ribeiro

Imitation learning, which learns agent policy by mimicking expert demonstration, has shown promising results in many applications such as medical treatment regimes and self-driving vehicles. However, it remains a difficult task to interpret…

Machine Learning · Computer Science 2024-01-31 Tianxiang Zhao , Wenchao Yu , Suhang Wang , Lu Wang , Xiang Zhang , Yuncong Chen , Yanchi Liu , Wei Cheng , Haifeng Chen

We aim to dismantle the prevalent black-box neural architectures used in complex visual reasoning tasks, into the proposed eXplainable and eXplicit Neural Modules (XNMs), which advance beyond existing neural module networks towards using…

Computer Vision and Pattern Recognition · Computer Science 2019-03-20 Jiaxin Shi , Hanwang Zhang , Juanzi Li

Graph generation poses a significant challenge as it involves predicting a complete graph with multiple nodes and edges based on simply a given label. This task also carries fundamental importance to numerous real-world applications,…

Machine Learning · Computer Science 2024-02-21 Xiandong Zou , Xiangyu Zhao , Pietro Liò , Yiren Zhao

The exploration of Graph Neural Networks (GNNs) for processing graph-structured data has expanded, particularly their potential for causal analysis due to their universal approximation capabilities. Anticipated to significantly enhance…

Machine Learning · Computer Science 2024-01-30 Simi Job , Xiaohui Tao , Taotao Cai , Lin Li , Haoran Xie , Jianming Yong

We study the problem of graph structure identification, i.e., of recovering the graph of dependencies among time series. We model these time series data as components of the state of linear stochastic networked dynamical systems. We assume…

Machine Learning · Computer Science 2023-06-29 Sérgio Machado , Anirudh Sridhar , Paulo Gil , Jorge Henriques , José M. F. Moura , Augusto Santos

Soybean leaf disease detection is critical for agricultural productivity but faces challenges due to visually similar symptoms and limited interpretability in conventional methods. While Convolutional Neural Networks (CNNs) excel in spatial…

Computer Vision and Pattern Recognition · Computer Science 2025-05-05 Md Abrar Jahin , Soudeep Shahriar , M. F. Mridha , Md. Jakir Hossen , Nilanjan Dey

A central goal in understanding human vision is to uncover the visual features that drive neuronal activity. A growing body of work has used artificial neural networks as encoding models to predict cortical responses to natural images,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Idan Daniel Grosbard , Mor Geva , Galit Yovel

Given a convex and differentiable objective $Q(\M)$ for a real symmetric matrix $\M$ in the positive definite (PD) cone -- used to compute Mahalanobis distances -- we propose a fast general metric learning framework that is entirely…

Machine Learning · Computer Science 2021-06-14 Cheng Yang , Gene Cheung , Wei Hu
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