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Gene finding is the task of identifying the locations of coding sequences within the vast amount of genetic code contained in the genome. With an ever increasing quantity of raw genome sequences, gene finding is an important avenue towards…

Genomics · Quantitative Biology 2025-05-07 Frederikke I. Marin , Dennis Pultz , Wouter Boomsma

This study presents a question-based knowledge encoding approach that improves retrieval-augmented generation (RAG) systems without requiring fine-tuning or traditional chunking. We encode textual content using generated questions that span…

We present a method that uses a Bloom filter transform to preprocess data for machine learning. Each sample is encoded into a compact bit-array representation using hash-based encoding, producing a fixed-length feature space that reduces…

Machine Learning · Computer Science 2026-05-11 John Cartmell , Mihaela Cardei , Ionut Cardei

Metagenomics sequencing is routinely applied to quantify bacterial abundances in microbiome studies, where the bacterial composition is estimated based on the sequencing read counts. Due to limited sequencing depth and DNA dropouts, many…

Methodology · Statistics 2019-04-26 Yuanpei Cao , Anru Zhang , Hongzhe Li

The reconstruction of microbial genomes from large metagenomic datasets is a critical procedure for finding uncultivated microbial populations and defining their microbial functional roles. To achieve that, we need to perform metagenomic…

Machine Learning · Computer Science 2021-11-19 Pengfei Zhang , Zhengyuan Jiang , Yixuan Wang , Yu Li

As the global need for large-scale data storage is rising exponentially, existing storage technologies are approaching their theoretical and functional limits in terms of density and energy consumption, making DNA based storage a potential…

Emerging Technologies · Computer Science 2021-10-12 Yotam Nahum , Eyar Ben-Tolila , Leon Anavy

We study the problem of compressing a source sequence in the presence of side-information that is related to the source via insertions, deletions and substitutions. We propose a simple algorithm to compress the source sequence when the…

Information Theory · Computer Science 2016-11-15 Nan Ma , Kannan Ramchandran , David Tse

Metagenomics has led to significant advances in many fields. Metagenomic analysis commonly involves the key tasks of determining the species present in a sample and their relative abundances. These tasks require searching large metagenomic…

Deep shotgun sequencing and analysis of genomes, transcriptomes, amplified single-cell genomes, and metagenomes has enabled investigation of a wide range of organisms and ecosystems. However, sampling variation in short-read data sets and…

Genomics · Quantitative Biology 2012-05-22 C. Titus Brown , Adina Howe , Qingpeng Zhang , Alexis B. Pyrkosz , Timothy H. Brom

Clustering is a core task in machine learning with wide-ranging applications in data mining and pattern recognition. However, its unsupervised nature makes it inherently challenging. Many existing clustering algorithms suffer from critical…

Machine Learning · Computer Science 2025-07-29 Ahmed Shokry , Ayman Khalafallah

Spectral clustering is one of the most popular clustering methods. However, the high computational cost due to the involved eigen-decomposition procedure can immediately hinder its applications in large-scale tasks. In this paper we use…

Machine Learning · Computer Science 2023-01-24 Yongyu Wang

While achieving a compression ratio of 2.0 bits/base, the new algorithm codes non-N bases in fixed length. It dramatically reduces the time of coding and decoding than previous DNA compression algorithms and some universal compression…

Information Theory · Computer Science 2007-07-16 Jie Liu , Sheng Bao , Zhiqiang Jing , Shi Chen

In this work, we update the unsupervised machine learning (UML) step by proposing an algorithm based on ConvNeXt large model coding to improve the efficiency of unlabeled galaxy morphology classifications. The method can be summarized into…

Astrophysics of Galaxies · Physics 2025-01-03 Guanwen Fang , Yao Dai , Zesen Lin , Chichun Zhou , Jie Song , Yizhou Gu , Xiaotong Guo , Anqi Mao , Xu Kong

Supervised cross-modal hashing has gained increasing research interest on large-scale retrieval task owning to its satisfactory performance and efficiency. However, it still has some challenging issues to be further studied: 1) most of them…

Machine Learning · Computer Science 2019-05-07 Tao Yao , Xiangwei Kong , Lianshan Yan , Wenjing Tang , Qi Tian

Scalable coding, which can adapt to channel bandwidth variation, performs well in today's complex network environment. However, most existing scalable compression methods face two challenges: reduced compression performance and insufficient…

Image and Video Processing · Electrical Eng. & Systems 2024-12-03 Yongqi Zhai , Yi Ma , Luyang Tang , Wei Jiang , Ronggang Wang

Logs are essential for diagnosing failures and conducting retrospective studies, leading many software organizations to retain log messages for a long time. Nevertheless, the volume of generated log data grows rapidly as software systems…

Software Engineering · Computer Science 2026-03-24 Shiwen Shan , Yintong Huo , Hongzhan Zhong , Zhining Wang , Yuxin Su , Zibin Zheng

Compressed sensing is an image reconstruction technique to achieve high-quality results from limited amount of data. In order to achieve this, it utilizes prior knowledge about the samples that shall be reconstructed. Focusing on image…

Recent advances in deep learning have led to superhuman performance across a variety of applications. Recently, these methods have been successfully employed to improve the rate-distortion performance in the task of image compression.…

Image and Video Processing · Electrical Eng. & Systems 2022-02-01 Ankur Mali , Alexander Ororbia , Daniel Kifer , Lee Giles

Over the past years, the ever-growing trend on data storage demand, more specifically for "cold" data (i.e. rarely accessed), has motivated research for alternative systems of data storage. Because of its biochemical characteristics,…

Image and Video Processing · Electrical Eng. & Systems 2023-05-11 Xavier Pic , Eva Gil San Antonio , Melpomeni Dimopoulou , Marc Antonini

In language processing, transformers benefit greatly from text being condensed. This is achieved through a larger vocabulary that captures word fragments instead of plain characters. This is often done with Byte Pair Encoding. In the…

Computer Vision and Pattern Recognition · Computer Science 2024-11-18 Tim Elsner , Paula Usinger , Julius Nehring-Wirxel , Gregor Kobsik , Victor Czech , Yanjiang He , Isaak Lim , Leif Kobbelt
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