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Physics-informed neural networks (PINNs) are able to solve partial differential equations (PDEs) by incorporating the residuals of the PDEs into their loss functions. Variational Physics-Informed Neural Networks (VPINNs) and hp-VPINNs use…

Partial differential equations (PDEs) are central to scientific modeling. Modern workflows increasingly rely on learning-based components to support model reuse, inference, and integration across large computational processes. Despite the…

Machine Learning · Computer Science 2026-02-20 Yilong Dai , Shengyu Chen , Ziyi Wang , Xiaowei Jia , Yiqun Xie , Vipin Kumar , Runlong Yu

The use of deep learning methods in scientific computing represents a potential paradigm shift in engineering problem solving. One of the most prominent developments is Physics-Informed Neural Networks (PINNs), in which neural networks are…

Machine Learning · Computer Science 2024-03-08 Pratanu Roy , Stephen Castonguay

In the field of pharmacokinetics and pharmacodynamics (PKPD) modeling, which plays a pivotal role in the drug development process, traditional models frequently encounter difficulties in fully encapsulating the complexities of drug…

Quantitative Methods · Quantitative Biology 2024-09-23 Nazanin Ahmadi Daryakenari , Shupeng Wang , George Karniadakis

We formulate and study a class of two-player zero-sum stochastic dynamic games with partial and asymmetric information. Information asymmetry introduces fundamental challenges involving \emph{belief representation} and \emph{theory of mind}…

Optimization and Control · Mathematics 2026-03-20 Yuxiang Guan , Iman Shames , Tyler Summers

Partial differential equations (PDEs) provide a mathematical foundation for simulating and understanding intricate behaviors in both physical sciences and engineering. With the growing capabilities of deep learning, data$-$driven approaches…

Machine Learning · Computer Science 2025-10-14 Narayan S Iyer , Bivas Bhaumik , Ram S Iyer , Satyasaran Changdar

In this study, we propose a new numerical scheme for physics-informed neural networks (PINNs) that enables precise and inexpensive solution for partial differential equations (PDEs) in case of arbitrary geometries while strictly enforcing…

Numerical Analysis · Mathematics 2024-07-30 Hamed Saidaoui , Luis Espath , Rául Tempone

In this paper, numerical methods using Physics-Informed Neural Networks (PINNs) are presented with the aim to solve higher-order ordinary differential equations (ODEs). Indeed, this deep-learning technique is successfully applied for…

Computational Physics · Physics 2023-07-17 Hubert Baty

The physics-informed neural network (PINN) is effective in solving the partial differential equation (PDE) by capturing the physics constraints as a part of the training loss function through the Automatic Differentiation (AD). This study…

Computational Physics · Physics 2022-02-17 Zixue Xiang , Wei Peng , Weien Zhou , Wen Yao

Inferring biophysical parameters and hidden state variables from partial and noisy observations is a fundamental challenge in computational neuroscience. This problem is particularly difficult for fast - slow spiking and bursting models,…

Neural and Evolutionary Computing · Computer Science 2026-03-11 Changliang Wei , Yangyang Wang , Xueyu Zhu

In this study, we introduce a method based on Separable Physics-Informed Neural Networks (SPINNs) for effectively solving the BGK model of the Boltzmann equation. While the mesh-free nature of PINNs offers significant advantages in handling…

Numerical Analysis · Mathematics 2025-07-11 Jaemin Oh , Seung Yeon Cho , Seok-Bae Yun , Eunbyung Park , Youngjoon Hong

Throughout many fields, practitioners often rely on differential equations to model systems. Yet, for many applications, the theoretical derivation of such equations and/or accurate resolution of their solutions may be intractable. Instead,…

Machine Learning · Computer Science 2025-01-16 Grant Norman , Jacqueline Wentz , Hemanth Kolla , Kurt Maute , Alireza Doostan

This paper presents a comprehensive review of the design of experiments used in the surrogate models. In particular, this study demonstrates the necessity of the design of experiment schemes for the Physics-Informed Neural Network (PINN),…

Machine Learning · Statistics 2022-02-15 Sourav Das , Solomon Tesfamariam

Policy gradient methods enjoy strong practical performance in numerous tasks in reinforcement learning. Their theoretical understanding in multiagent settings, however, remains limited, especially beyond two-player competitive and potential…

Computer Science and Game Theory · Computer Science 2023-12-22 Ioannis Anagnostides , Ioannis Panageas , Gabriele Farina , Tuomas Sandholm

We study the numerical approximation of a time-dependent variational mean field game system with local couplings and either periodic or Neumann boundary conditions. Following a variational approach, we employ a finite difference…

Numerical Analysis · Mathematics 2026-01-06 Heidi Wolles Ljósheim , Dante Kalise , John W. Pearson , Francisco J. Silva

Physics-Informed Neural Networks (PINNs) recast PDE solving as an optimisation problem in function space by minimising a residual-based objective, yet many applications require additional derivative-based relations that are just as…

Machine Learning · Computer Science 2026-04-16 Kentaro Hoshisashi , Carolyn E Phelan , Paolo Barucca

Physics-Informed Neural Networks (PINN) has evolved into a powerful tool for solving partial differential equations, which has been applied to various fields such as energy, environment, en-gineering, etc. When utilizing PINN to solve…

Fluid Dynamics · Physics 2024-11-27 Zijie Su , Yunpu Liu , Sheng Pan , Zheng Li , Changyu Shen

We study a class of two-player zero-sum stochastic games known as \textit{blind stochastic games}, where players neither observe the state nor receive any information about it during the game. A central concept for analyzing long-duration…

Optimization and Control · Mathematics 2025-11-24 Krishnendu Chatterjee , David Lurie , Raimundo Saona , Bruno Ziliotto

We consider a stochastic differential game in the context of forward-backward stochastic differential equations, where one player implements an impulse control while the opponent controls the system continuously. Utilizing the notion of…

Optimization and Control · Mathematics 2021-12-20 Magnus Perninge

Accurately simulating systems governed by PDEs, such as voltage fields in cardiac electrophysiology (EP) modelling, remains a significant modelling challenge. Traditional numerical solvers are computationally expensive and sensitive to…

Machine Learning · Computer Science 2026-04-22 Hannah Lydon , Milad Kazemi , Martin Bishop , Nicola Paoletti
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