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Thyroid cancer is currently the fifth most common malignancy diagnosed in women. Since differentiation of cancer sub-types is important for treatment and current, manual methods are time consuming and subjective, automatic computer-aided…

We consider preoperative prediction of thyroid cancer based on ultra-high-resolution whole-slide cytopathology images. Inspired by how human experts perform diagnosis, our approach first identifies and classifies diagnostic image regions…

Computer Vision and Pattern Recognition · Computer Science 2020-02-11 David Dov , Shahar Kovalsky , Jonathan Cohen , Danielle Range , Ricardo Henao , Lawrence Carin

Thyroid cancer is a common endocrine carcinoma that occurs in the thyroid gland. Much effort has been invested in improving its diagnosis, and thyroidectomy remains the primary treatment method. A successful operation without unnecessary…

Machine Learning · Computer Science 2022-03-31 Nan Miles Xi , Lin Wang , Chuanjia Yang

Ultrasound-based risk stratification of thyroid nodules is a critical clinical task, but it suffers from high inter-observer variability. While many deep learning (DL) models function as "black boxes," we propose a fully automated,…

Image and Video Processing · Electrical Eng. & Systems 2025-11-18 Omar Abdelrazik , Mohamed Elsayed , Noorul Wahab , Nasir Rajpoot , Adam Shephard

Thyroid disorders are most commonly diagnosed using high-resolution Ultrasound (US). Longitudinal nodule tracking is a pivotal diagnostic protocol for monitoring changes in pathological thyroid morphology. This task, however, imposes a…

Image and Video Processing · Electrical Eng. & Systems 2023-09-04 Lennart Bastian , Vincent Bürgin , Ha Young Kim , Alexander Baumann , Benjamin Busam , Mahdi Saleh , Nassir Navab

The most prevalent form of bladder cancer is urothelial carcinoma, characterized by a high recurrence rate and substantial lifetime treatment costs for patients. Grading is a prime factor for patient risk stratification, although it suffers…

Image and Video Processing · Electrical Eng. & Systems 2024-05-27 Saul Fuster , Umay Kiraz , Trygve Eftestøl , Emiel A. M. Janssen , Kjersti Engan

We consider machine-learning-based thyroid-malignancy prediction from cytopathology whole-slide images (WSI). Multiple instance learning (MIL) approaches, typically used for the analysis of WSIs, divide the image (bag) into patches…

Thyroid cancer is said to be the second most common type of cancer in female individuals and the third in males by 2030, according to projections. In general, detecting cancer in its early stages improves the chance of survival of the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-29 J. R. González , É. O. Rodrigues , C. P. Damião , C. A. P. Fontes , A. C. Silva , A. C. Paiva , H. Li , C. Du , A. Conci

Current approaches for classification of whole slide images (WSI) in digital pathology predominantly utilize a two-stage learning pipeline. The first stage identifies areas of interest (e.g. tumor tissue), while the second stage processes…

Computer Vision and Pattern Recognition · Computer Science 2022-07-20 Marvin Teichmann , Andre Aichert , Hanibal Bohnenberger , Philipp Ströbel , Tobias Heimann

Purpose: Thyroid cancer has been a common cancer. Papillary thyroid cancer and follicular thyroid cancer are the two most common types of thyroid cancer. Follicular thyroid cancer lacks distinctive ultrasound signs and is more difficult to…

Machine Learning · Computer Science 2025-09-17 Songlin Zhou , Tao Zhou , Xin Li , Stephen Shing-Toung Yau

In this study, we develop a new CAD system for accurate thyroid cancer classification with emphasis on feature extraction. Prior studies have shown that thyroid texture is important for segregating the thyroid ultrasound images into…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Saurabh Saini , Kapil Ahuja , Marc C. Steinbach , Thomas Wick

With the development of digital imaging in medical microscopy, artificial intelligent-based analysis of pathological whole slide images (WSIs) provides a powerful tool for cancer diagnosis. Limited by the expensive cost of pixel-level…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Jiawen Li , Qiehe Sun , Renao Yan , Yizhi Wang , Yuqiu Fu , Yani Wei , Tian Guan , Huijuan Shi , Yonghonghe He , Anjia Han

Thyroid cancer is common worldwide, with a rapid increase in prevalence across North America in recent years. While most patients present with palpable nodules through physical examination, a large number of small and medium-sized nodules…

Image and Video Processing · Electrical Eng. & Systems 2020-06-11 Fatemeh Abdolali , Atefeh Shahroudnejad , Abhilash Rakkunedeth Hareendranathan , Jacob L Jaremko , Michelle Noga , Kumaradevan Punithakumar

Thyroid nodule classification and segmentation in ultrasound images are crucial for computer-aided diagnosis; however, they face limitations owing to insufficient labeled data. In this study, we proposed a multi-view contrastive…

Computer Vision and Pattern Recognition · Computer Science 2024-02-20 Jian Wang , Xin Yang , Xiaohong Jia , Wufeng Xue , Rusi Chen , Yanlin Chen , Xiliang Zhu , Lian Liu , Yan Cao , Jianqiao Zhou , Dong Ni , Ning Gu

Thyroid ultrasound is the first-line exam for assessing thyroid nodules and determining whether biopsy is warranted. In routine reporting, radiologists produce two coupled outputs: a nodule contour for measurement and a TI-RADS risk…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Dina Salama , Mohamed Mahmoud , Nourhan Bayasi , David Liu , Ilker Hacihaliloglu

Thyroid nodule classification using ultrasound imaging is essential for early diagnosis and clinical decision-making; however, despite promising performance on in-distribution data, existing deep learning methods often exhibit limited…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Yangmei Chen , Zhongyuan Zhang , Xikun Zhang , Xinyu Hao , Mingliang Hou , Renqiang Luo , Ziqi Xu

Multiple instance learning exhibits a powerful approach for whole slide image-based diagnosis in the absence of pixel- or patch-level annotations. In spite of the huge size of hole slide images, the number of individual slides is often…

The increasing prevalence of thyroid cancer globally has led to the development of various computer-aided detection methods. Accurate segmentation of thyroid nodules is a critical first step in the development of AI-assisted clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Mahmoud El Hussieni

Thyroid carcinoma, a significant yet often controllable cancer, has seen a rise in cases, largely due to advancements in diagnostic methods. Differentiated thyroid cancer (DTC), which includes papillary and follicular varieties, is…

Machine Learning · Computer Science 2025-05-06 Mohammad Al-Sayed Ahmad , Jude Haddad

Over the past decades, the incidence of thyroid cancer has been increasing globally. Accurate and early diagnosis allows timely treatment and helps to avoid over-diagnosis. Clinically, a nodule is commonly evaluated from both transverse and…

Computer Vision and Pattern Recognition · Computer Science 2022-07-04 Han Huang , Yijie Dong , Xiaohong Jia , Jianqiao Zhou , Dong Ni , Jun Cheng , Ruobing Huang
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