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This paper deals with a new design methodology for stratified comparative experiments based on interacting reinforced urn systems. The key idea is to model the interaction between urns for borrowing information across strata and to use it…

Causal inference has numerous real-world applications in many domains, such as health care, marketing, political science, and online advertising. Treatment effect estimation, a fundamental problem in causal inference, has been extensively…

Machine Learning · Computer Science 2023-02-03 Zhixuan Chu , Jianmin Huang , Ruopeng Li , Wei Chu , Sheng Li

Social network interference induces complex dependencies where a unit's outcome is influenced not only by its own exposure and mediator but also by those of connected neighbors. In such settings, a significant challenge lies in…

Methodology · Statistics 2026-03-03 Ritoban Kundu , Peter X. K. Song

There is a movement in design of experiments away from the classic randomization put forward by Fisher, Cochran and others to one based on optimization. In fixed-sample trials comparing two groups, measurements of subjects are known in…

Methodology · Statistics 2018-10-22 Adam Kapelner , Abba M. Krieger , Uri Shalit , David Azriel

Existing effect measures for compositional features are inadequate for many modern applications, for example, in microbiome research, since they display traits such as high-dimensionality and sparsity that can be poorly modelled with…

Methodology · Statistics 2025-06-02 Anton Rask Lundborg , Niklas Pfister

Rerandomization is a modern experimental design technique that repeatedly randomizes treatment assignments until covariates are deemed balanced between treatment groups. This enhances the precision and coherence of causal effect estimators,…

Methodology · Statistics 2025-12-08 Antônio Carlos Herling Ribeiro Junior , Zach Branson

I run Monte Carlo simulations of content production over random Watts-Strogatz graphs to show various effects relevant to modeling and understanding Randomized Controlled Trials on social networks: the network effect, spillover effect,…

Social and Information Networks · Computer Science 2023-12-05 Márton Trencséni

We contemplate an experimental situation in a $2^k$-factorial experiment with acute resource crunch so that we need to conduct just a saturated design [SD] - with the understanding that precision of the estimates cannot be estimated from…

Statistics Theory · Mathematics 2019-11-01 Francois Domagni , Samad Hedayat , Sinha Bikas

Empirical research plays a fundamental role in the machine learning domain. At the heart of impactful empirical research lies the development of clear research hypotheses, which then shape the design of experiments. The execution of…

Machine Learning · Computer Science 2024-05-29 Daniel Vranješ , Oliver Niggemann

A fundamental problem in network experiments is selecting an appropriate experimental design in order to precisely estimate a given causal effect of interest. In this work, we propose the Conflict Graph Design, a general approach for…

Methodology · Statistics 2026-01-14 Vardis Kandiros , Charilaos Pipis , Constantinos Daskalakis , Christopher Harshaw

We derive computationally tractable methods to select a small subset of experiment settings from a large pool of given design points. The primary focus is on linear regression models, while the technique extends to generalized linear models…

Machine Learning · Statistics 2017-12-21 Yining Wang , Adams Wei Yu , Aarti Singh

According to Hansen, Madow and Tepping [J. Amer. Statist. Assoc. 78 (1983) 776--793], "Probability sampling designs and randomization inference are widely accepted as the standard approach in sample surveys." In this article, reasons are…

Methodology · Statistics 2011-08-12 J. N. K. Rao

Randomized controlled trials are not only the golden standard in medicine and vaccine trials but have spread to many other disciplines like behavioral economics, making it an important interdisciplinary tool for scientists. When designing…

Methodology · Statistics 2021-11-30 Tassilo Schwarz

Exposure mappings are widely used to model potential outcomes in the presence of interference, where each unit's outcome may depend not only on its own treatment, but also on the treatment of other units as well. However, in practice these…

Methodology · Statistics 2018-07-02 David Choi

Behavioral health interventions, such as trainings or incentives, are implemented in settings where individuals are interconnected, and the intervention assigned to some individuals may also affect others within their network. Evaluating…

Methodology · Statistics 2025-02-17 Zhibing He , Junhan Fan , Ashley Buchanan , Donna Spiegelman , Laura Forastiere

Randomized experiments are the gold standard for investigating causal relationships, with comparisons of potential outcomes under different treatment groups used to estimate treatment effects. However, outcomes with heavy-tailed…

Methodology · Statistics 2024-07-09 Hongzi Li , Wei Ma , Yingying Ma , Hanzhong Liu

Several problems in statistics involve the combination of high-variance unbiased estimators with low-variance estimators that are only unbiased under strong assumptions. A notable example is the estimation of causal effects while combining…

Methodology · Statistics 2023-05-25 Michael Oberst , Alexander D'Amour , Minmin Chen , Yuyan Wang , David Sontag , Steve Yadlowsky

It has been argued for many years that models used to analyze data from crossover designs are not appropriate when simple carryover effects are assumed. Furthermore, a statistical model that could estimate complex carry-over effects in…

Methodology · Statistics 2025-08-22 N. A. Cruz , K. Mylona , O. O. Melo

Strip-plot designs are very useful when the treatments have a factorial structure and the factors levels are hard-to-change. We develop a randomization-based theory of causal inference from such designs in a potential outcomes framework.…

Statistics Theory · Mathematics 2018-05-18 Fatemah A. Alquallaf , S. Huda , Rahul Mukerjee

Understanding causality should be a core requirement of any attempt to build real impact through AI. Due to the inherent unobservability of counterfactuals, large randomised trials (RCTs) are the standard for causal inference. But large…