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Now that disease-modifying therapies for Alzheimer disease have been approved by regulatory agencies, the early, objective, and accurate clinical diagnosis of AD based on the lowest-cost measurement modalities possible has become an…
The continuous effort towards topological quantum devices calls for an efficient and non-invasive method to assess the conformity of components in different topological phases. Here, we show that machine learning paves the way towards…
Image registration between histology and magnetic resonance imaging (MRI) is a challenging task due to differences in structural content and contrast. Too thick and wide specimens cannot be processed all at once and must be cut into smaller…
The volume estimation of brain regions from MRI data is a key problem in many clinical applications, where the acquisition of data at high spatial resolution is desirable. While parallel MRI and constrained image reconstruction algorithms…
This paper presents a new framework for human body part segmentation based on Deep Convolutional Neural Networks trained using only synthetic data. The proposed approach achieves cutting-edge results without the need of training the models…
Most deep learning models in medical imaging are trained on adult data with unclear performance on pediatric images. In this work, we aim to address this challenge in the context of automated anatomy segmentation in whole-body Computed…
Magnetic resonance imaging (MRI) is the non-invasive modality of choice for body tissue composition analysis due to its excellent soft tissue contrast and lack of ionizing radiation. However, quantification of body composition requires an…
Semantic segmentation is one of the most fundamental tasks in image understanding with a long history of research, and subsequently a myriad of different approaches. Traditional methods strive to train models up from scratch, requiring vast…
As machine learning gets adopted into the industry quickly, trustworthiness is increasingly in focus. Yet, efficiency and sustainability of robust training pipelines still have to be established. In this work, we consider a simple pipeline…
We use methods from computational algebraic topology to study functional brain networks, in which nodes represent brain regions and weighted edges encode the similarity of fMRI time series from each region. With these tools, which allow one…
This paper presents a new mesh segmentation method that integrates geometrical and topological features through a flexible Reeb graph representation. The algorithm consists of three phases: construction of the Reeb graph using the improved…
Medical segmentation is performed to determine the bounds of regions of interest (ROI) prior to surgery. By allowing the study of growth, structure, and behaviour of the ROI in the planning phase, critical information can be obtained,…
We present a fully automated, anatomically guided deep learning pipeline for prostate cancer (PCa) risk stratification using routine MRI. The pipeline integrates three key components: an nnU-Net module for segmenting the prostate gland and…
Magnetic Resonance Imaging (MRI) is essential for noninvasive generation of high-quality images of human tissues. Accurate segmentation of MRI data is critical for medical applications like brain anatomy analysis and disease detection.…
Amodal segmentation aims to predict segmentation masks for both the visible and occluded regions of an object. Most existing works formulate this as a supervised learning problem, requiring manually annotated amodal masks or synthetic…
The paper discusses the use of MRI for segmentation techniques, specifically focusing on brain tumor detection. It discusses the use of convolutional neural networks (CNN) for automatic segmentation but also discusses challenges such as…
Early diagnosis and accurate segmentation of brain tumors are imperative for successful treatment. Unfortunately, manual segmentation is time consuming, costly and despite extensive human expertise often inaccurate. Here, we present an…
We apply a deep convolutional neural network segmentation model to enable novel automated microstructure segmentation applications for complex microstructures typically evaluated manually and subjectively. We explore two microstructure…
MRI tumor segmentation remains a critical challenge in medical imaging, where volumetric analysis faces unique computational demands due to the complexity of 3D data. The spatially sequential arrangement of adjacent MRI slices provides…
Mild cognitive impairment (MCI) is characterized by subtle changes in cognitive functions, often associated with disruptions in brain connectivity. The present study introduces a novel fine-grained analysis to examine topological…