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Related papers: Robust single-particle cryo-EM image denoising and…

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Recovering images corrupted by multiplicative noise is a well known challenging task. Motivated by the success of multiscale hierarchical decomposition methods (MHDM) in image processing, we adapt a variety of both classical and new…

Numerical Analysis · Mathematics 2023-10-11 Joel Barnett , Wen Li , Elena Resmerita , Luminita Vese

Dielectric tensor tomography is an imaging technique for mapping three-dimensional distributions of dielectric properties in transparent materials. This work introduces an enhanced illumination strategy employing a micro-electromechanical…

In cryo-electron microscopy (EM), molecular structures are determined from large numbers of projection images of individual particles. To harness the full power of this single-molecule information, we use the Bayesian inference of EM…

Biomolecules · Quantitative Biology 2018-01-17 Pilar Cossio , David Rohr , Fabio Baruffa , Markus Rampp , Volker Lindenstruth , Gerhard Hummer

Despite today's prevalence of ultrasound imaging in medicine, ultrasound signal-to-noise ratio is still affected by several sources of noise and artefacts. Moreover, enhancing ultrasound image quality involves balancing concurrent factors…

Image and Video Processing · Electrical Eng. & Systems 2024-06-18 Yuxin Zhang , Clément Huneau , Jérôme Idier , Diana Mateus

We propose a new microscopy simulation system that can depict atomistic models in a micrograph visual style, similar to results of physical electron microscopy imaging. This system is scalable, able to represent simulation of electron…

Quantitative Methods · Quantitative Biology 2026-03-27 Ngan Nguyen , Feng Liang , Dominik Engel , Ciril Bohak , Peter Wonka , Timo Ropinski , Ivan Viola

Incoherent k-space undersampling and deep learning-based reconstruction methods have shown great success in accelerating MRI. However, the performance of most previous methods will degrade dramatically under high acceleration factors, e.g.,…

Image and Video Processing · Electrical Eng. & Systems 2026-01-21 Jin Liu , Qing Lin , Zhuang Xiong , Shanshan Shan , Chunyi Liu , Min Li , Feng Liu , G. Bruce Pike , Hongfu Sun , Yang Gao

Single-particle cryo-Electron Microscopy (EM) has become a popular technique for determining the structure of challenging biomolecules that are inaccessible to other technologies. Recent advances in automation, both in data collection and…

Computer Vision and Pattern Recognition · Computer Science 2021-05-31 Ye Zhou , Amit Moscovich , Tamir Bendory , Alberto Bartesaghi

Recent years have witnessed the remarkable performance of diffusion models in various vision tasks. However, for image restoration that aims to recover clear images with sharper details from given degraded observations, diffusion-based…

Computer Vision and Pattern Recognition · Computer Science 2023-10-10 Liyan Wang , Qinyu Yang , Cong Wang , Wei Wang , Jinshan Pan , Zhixun Su

Image denoising is a fundamental problem in image processing whose primary objective is to remove the noise while preserving the original image structure. In this work, we proposed a new architecture for image denoising. We have used…

Image and Video Processing · Electrical Eng. & Systems 2019-03-25 Sutanu Bera , Avisek Lahiri , Prabir Kumar Biswas

We present a geometry-aware method for heterogeneous single-particle cryogenic electron microscopy (cryo-EM) reconstruction that predicts atomic backbone conformations. To incorporate protein-structure priors, we represent the backbone as a…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Jonathan Krook , Axel Janson , Joakim Andén , Melanie Weber , Ozan Öktem

Dual-energy X-ray Computed Tomography (DECT) constitutes an advanced technology which enables automatic decomposition of materials in clinical images without manual segmentation using the dependency of the X-ray linear attenuation with…

Image and Video Processing · Electrical Eng. & Systems 2025-07-25 Hang Xu , Alexandre Bousse , Alessandro Perelli

We introduce ICE-TIDE, a method for cryogenic electron tomography (cryo-ET) that simultaneously aligns observations and reconstructs a high-resolution volume. The alignment of tilt series in cryo-ET is a major problem limiting the…

Image and Video Processing · Electrical Eng. & Systems 2024-12-16 Valentin Debarnot , Vinith Kishore , Ricardo D. Righetto , Ivan Dokmanić

The number of noisy images required for molecular reconstruction in single-particle cryo-electron microscopy (cryo-EM) is governed by the autocorrelations of the observed, randomly-oriented, noisy projection images. In this work, we…

Numerical Analysis · Mathematics 2023-05-03 Tamir Bendory , Yuehaw Khoo , Joe Kileel , Oscar Mickelin , Amit Singer

We propose a deconvolution algorithm for images blurred and degraded by a Poisson noise. The algorithm uses a fast proximal backward-forward splitting iteration. This iteration minimizes an energy which combines a \textit{non-linear} data…

Applications · Statistics 2008-12-18 François-Xavier Dupé , Jalal Fadili , Jean Luc Starck

Ultrasound image reconstruction can be approximately cast as a linear inverse problem that has traditionally been solved with penalized optimization using the $l_1$ or $l_2$ norm, or wavelet-based terms. However, such regularization…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Yuxin Zhang , Clément Huneau , Jérôme Idier , Diana Mateus

Cryo-electron microscopy is a revolutionary technique that can provide 3D density maps at near-atomic resolution. However, map validation is still an open issue in the field. Despite several efforts from the community, it is possible to…

Biological Physics · Physics 2019-08-06 Sebastian Ortiz , Luka Stanisic , Boris A Rodriguez , Markus Rampp , Gerhard Hummer , Pilar Cossio

Background and Objective: The contrast of cryo-EM images varies from one to another, primarily due to the uneven thickness of the ice layer. This contrast variation can affect the quality of 2-D class averaging, 3-D ab-initio modeling, and…

Computer Vision and Pattern Recognition · Computer Science 2022-07-01 Yunpeng Shi , Amit Singer

This paper introduces two key contributions aimed at improving the speed and quality of images generated through inverse diffusion processes. The first contribution involves reparameterizing the diffusion process in terms of the angle on a…

Machine Learning · Computer Science 2026-02-26 Zhenkai Zhang , Krista A. Ehinger , Tom Drummond

The dynamics of biomolecules are crucial for our understanding of their functioning in living systems. However, current 3D imaging techniques, such as cryogenic electron microscopy (cryo-EM), require freezing the sample, which limits the…

Quantitative Methods · Quantitative Biology 2023-08-24 Enze Ye , Yuhang Wang , Hong Zhang , Yiqin Gao , Huan Wang , He Sun

Ultrafast electron beam X-ray computed tomography produces noisy data due to short measurement times, causing reconstruction artifacts and limiting overall image quality. To counteract these issues, two self-supervised deep learning methods…

Machine Learning · Computer Science 2025-11-24 Israt Jahan Tulin , Sebastian Starke , Dominic Windisch , André Bieberle , Peter Steinbach