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An asymptotic analysis of the Gunn effect in two-dimensional samples of bulk n-GaAs with circular contacts is presented. A moving pulse far from contacts is approximated by a moving free boundary separating regions where the electric…

Materials Science · Physics 2009-11-10 L. L. Bonilla , R. Escobedo , F. J. Higuera

The one-dimensional crawling movement of a cell is considered in this theoretical study. Our active gel model shows that for a cell with weakly mechanosensitive adhesion complexes, as myosin contractility increases, a cell starts to move at…

Soft Condensed Matter · Physics 2023-01-05 Jen-Yu Lo , Yuan-Heng Tseng , Hsuan-Yi Chen

We study the motion of a compressible perfect liquid body in vacuum. This can be thought of as a model for the motion of the ocean or a star. The free surface moves with the velocity of the liquid and the pressure vanishes on the free…

Analysis of PDEs · Mathematics 2009-11-11 Hans Lindblad

We study the problem of the motion of the free surface of a liquid. We prove existence and stability for the linearized equations.

Analysis of PDEs · Mathematics 2007-05-23 Hans Lindblad

Cell polarity and movement are fundamental to many biological functions. Experimental and theoretically studies have indicated that interactions of certain proteins lead to the cell polarization which plays a key role in controlling the…

Dynamical Systems · Mathematics 2022-08-12 Shuang Liu , Li-Tien Cheng , Bo Li

The evolution problem for a membrane based model of an electrostatically actuated microelectromechanical system (MEMS) is studied. The model describes the dynamics of the membrane displacement and the electric potential. The latter is a…

Analysis of PDEs · Mathematics 2012-11-27 Joachim Escher , Philippe Laurencot , Christoph Walker

In the absence of environmental cues, a migrating cell performs an isotropic random motion. Recently, the breaking of this isotropy has been observed when cells move in the presence of asymmetric adhesive patterns. However, up to now the…

Soft Condensed Matter · Physics 2015-06-17 M. Le Berre , Yan-Jun Liu , J. Hu , P. Maiuri , O. Bénichou , R. Voituriez , Y. Chen , M. Piel

A mutualist model with nonlocal diffusions and a free boundary is first considered. We prove that this problem has a unique solution defined $t\ge0$, and its dynamics are governed by a spreading-vanishing dichotomy. Some criteria for…

Analysis of PDEs · Mathematics 2021-10-28 Lei Li , Mingxin Wang

Adhesive cell-substrate interactions are crucial for cell motility and are responsible for the necessary traction that propels cells. These interactions can also change the shape of the cell, analogous to liquid droplet wetting on adhesive…

We study a free boundary problem modelling the growth of non-necrotic tumors with fluid-like tissues. The fluid velocity satisfies Stokes equations with a source determined by the proliferation rate of tumor cells which depends on the…

Analysis of PDEs · Mathematics 2008-06-10 Junde Wu , Shangbin Cui

We study a free boundary problem on the lattice whose scaling limit is a harmonic free boundary problem with a discontinuous Hamiltonian. We find an explicit formula for the Hamiltonian, prove the solutions are unique, and prove that the…

Analysis of PDEs · Mathematics 2018-11-14 William M Feldman , Charles K Smart

We consider a parabolic non-local free boundary problem that has been derived as a limit of a bulk-surface reaction-diffusion system which models cell polarization. The authors have justified the well-posedness of this problem and have…

Analysis of PDEs · Mathematics 2023-04-24 Anna Logioti , Barbara Niethammer , Matthias Röger , Juan J. L. Velázquez

This paper deals with the evolution equation of a curve obtained as the sharp interface limit of a non-linear system of two reaction-diffusion PDEs. This system was introduced as a phase-field model of (crawling) motion of eukaryotic cells…

Analysis of PDEs · Mathematics 2016-03-23 Matthew S. Mizuhara , Leonid Berlyand , Volodymyr Rybalko , Lei Zhang

We study stationary free boundary configurations of an ideal incompressible magnetohydrodynamic fluid possessing nested flux surfaces. In 2D simply connected domains, we prove that if the magnetic field and velocity field are never…

Analysis of PDEs · Mathematics 2022-06-22 Peter Constantin , Theodore D. Drivas , Daniel Ginsberg

The conventional no-slip boundary condition leads to a non-integrable stress singularity at a contact line. This is a main challenge in numerical simulations of two-phase flows with moving contact lines. We derive a two-dimensional…

Fluid Dynamics · Physics 2019-05-23 Hanna Holmgren , Gunilla Kreiss

The initiation of directional cell motion requires symmetry breaking that can happen both with or without external stimuli. During cell crawling, forces generated by the cytoskeleton and their transmission through mechanosensitive adhesions…

Cell Behavior · Quantitative Biology 2023-06-02 Yuzhu Chen , David Saintillan , Padmini Rangamani

The actin cytoskeleton of cells is in continuous motion due to both polymerization of new filaments and their contraction by myosin II molecular motors. Through adhesion to the substrate, such intracellular flow can be converted into cell…

Subcellular Processes · Quantitative Biology 2021-08-11 Oliver M. Drozdowski , Falko Ziebert , Ulrich S. Schwarz

Amoeboid motion is a dynamic mode of cell motility essential for processes such as the immune response and wound healing. This review examines recent developments in the mathematical and computational modeling of amoeboid crawling, focusing…

Biological Physics · Physics 2026-03-17 Sergio Alonso , Carsten Beta

Thin fluid or elastic films and membranes are found in nature and technology, for instance, as confinements of living cells or in loudspeakers. When applying a net force, resulting flows in an unbounded two-dimensional incompressible…

Soft Condensed Matter · Physics 2022-11-29 Tyler Lutz , Sonja K. Richter , Andreas M. Menzel

Tissue boundaries pattern embryos, suppress tumours, and provide directional cues. Tissue boundaries are associated with supracellular cables formed by actin and the molecular motor non-muscle myosin II. Actomyosin cables generate tension…