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In recent years, large pre-trained language models (LLMs) have demonstrated the ability to follow instructions and perform novel tasks from a few examples. The possibility to parameterise an LLM through such in-context examples widens their…

Machine Learning · Computer Science 2023-05-10 Imanol Schlag , Sainbayar Sukhbaatar , Asli Celikyilmaz , Wen-tau Yih , Jason Weston , Jürgen Schmidhuber , Xian Li

Addressing the complexity of accurately classifying International Classification of Diseases (ICD) codes from medical discharge summaries is challenging due to the intricate nature of medical documentation. This paper explores the use of…

Machine Learning · Computer Science 2024-11-12 Zeyd Boukhers , AmeerAli Khan , Qusai Ramadan , Cong Yang

Recent work exploring the capabilities of pre-trained large language models (LLMs) has demonstrated their ability to act as general pattern machines by completing complex token sequences representing a wide array of tasks, including…

Computers and Society · Computer Science 2024-03-25 Seyed Parsa Neshaei , Richard Lee Davis , Adam Hazimeh , Bojan Lazarevski , Pierre Dillenbourg , Tanja Käser

Deep learning is playing a vital role in every field which involves data. It has emerged as a strong and efficient framework that can be applied to a broad spectrum of complex learning problems which were difficult to solve using…

Biomolecules · Quantitative Biology 2022-09-23 Faisal Ghaffar , Sarwar Khan , Gaddisa O. , Chen Yu-jhen

Protein language models (PLMs) learn contextual representations from protein sequences and are profoundly impacting various scientific disciplines spanning protein design, drug discovery, and structural predictions. One particular research…

Quantitative Methods · Quantitative Biology 2024-02-07 Andreas Dounas , Tudor-Stefan Cotet , Alexander Yermanos

Associative learning--forming links between co-occurring items--is fundamental to human cognition, reshaping internal representations in complex ways. Testing hypotheses on how representational changes occur in biological systems is…

Machine Learning · Computer Science 2025-10-27 Camila Kolling , Vy Ai Vo , Mariya Toneva

Recently, Antimicrobial peptides (AMPs) have been an area of interest in the researches, as the first line of defense against the bacteria. They are raising attention as an efficient way of fighting multidrug resistance. Discovering and…

Quantitative Methods · Quantitative Biology 2020-05-06 Neda Zarayeneh , Zahra Hanifeloo

Large Language Models (LLMs), such as ChatGPT, have taken the world by storm and have passed certain forms of the Turing test. However, LLMs are not limited to human language and analyze sequential data, such as DNA, protein, and gene…

Genomics · Quantitative Biology 2024-01-08 Hilbert Yuen In Lam , Xing Er Ong , Marek Mutwil

This study proposes a text classification algorithm based on large language models, aiming to address the limitations of traditional methods in capturing long-range dependencies, understanding contextual semantics, and handling class…

Computation and Language · Computer Science 2025-12-11 Ning Lyu , Yuxi Wang , Feng Chen , Qingyuan Zhang

The exponential increase in scientific literature and online information necessitates efficient methods for extracting knowledge from textual data. Natural language processing (NLP) plays a crucial role in addressing this challenge,…

Computation and Language · Computer Science 2025-10-22 Zhyar Rzgar K. Rostam , Gábor Kertész

Large Language Models (LLMs) have emerged as powerful tools in the field of Natural Language Processing (NLP) and have recently gained significant attention in the domain of Recommendation Systems (RS). These models, trained on massive…

Information Retrieval · Computer Science 2024-06-19 Likang Wu , Zhi Zheng , Zhaopeng Qiu , Hao Wang , Hongchao Gu , Tingjia Shen , Chuan Qin , Chen Zhu , Hengshu Zhu , Qi Liu , Hui Xiong , Enhong Chen

Large language models (LLMs) tend to inadequately integrate input context during text generation, relying excessively on encoded prior knowledge in model parameters, potentially resulting in generated text with factual inconsistencies or…

Computation and Language · Computer Science 2024-05-07 Zheng Zhao , Emilio Monti , Jens Lehmann , Haytham Assem

Large Language Models (LLMs) exhibit emerging in-context learning abilities through prompt engineering. The recent progress in large-scale generative models has further expanded their use in real-world language applications. However, the…

Computation and Language · Computer Science 2024-04-12 Linyi Yang , Shuibai Zhang , Zhuohao Yu , Guangsheng Bao , Yidong Wang , Jindong Wang , Ruochen Xu , Wei Ye , Xing Xie , Weizhu Chen , Yue Zhang

Modern natural language processing (NLP) methods employ self-supervised pretraining objectives such as masked language modeling to boost the performance of various application tasks. These pretraining methods are frequently extended with…

Computation and Language · Computer Science 2021-02-26 Nils Rethmeier , Isabelle Augenstein

We conduct a large-scale study of language models for chord prediction. Specifically, we compare N-gram models to various flavours of recurrent neural networks on a comprehensive dataset comprising all publicly available datasets of…

Machine Learning · Computer Science 2018-04-06 Filip Korzeniowski , David R. W. Sears , Gerhard Widmer

Pretraining DNA language models (DNALMs) on the full human genome is resource-intensive, yet often considered necessary for strong downstream performance. Inspired by recent findings in NLP and long-context modeling, we explore an…

Genomics · Quantitative Biology 2025-06-24 Sohan Mupparapu , Parameswari Krishnamurthy , Ratish Puduppully

Backdoor attacks manipulate model predictions by inserting innocuous triggers into training and test data. We focus on more realistic and more challenging clean-label attacks where the adversarial training examples are correctly labeled.…

Machine Learning · Computer Science 2023-10-31 Wencong You , Zayd Hammoudeh , Daniel Lowd

Drug repurposing is often framed as a candidate identification task, but existing approaches provide limited guidance for distinguishing biologically plausible candidates from historically well-connected ones. Here we introduce DrugKLM, a…

A recent trend in Natural Language Processing is the exponential growth in Language Model (LM) size, which prevents research groups without a necessary hardware infrastructure from participating in the development process. This study…

Computation and Language · Computer Science 2023-01-31 Jan Philip Wahle

Large Language Models (LLMs) have revolutionised the field of Natural Language Processing (NLP) and have achieved state-of-the-art performance in practically every task in this field. However, the prevalent approach used in text generation,…

Computation and Language · Computer Science 2024-08-12 Nicolo Micheletti , Samuel Belkadi , Lifeng Han , Goran Nenadic