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Multicellular systems play a key role in bioprocess and biomedical engineering. Cell ensembles encountered in these setups show phenotypic variability like size and biochemical composition. As this variability may result in undesired…

Systems and Control · Computer Science 2018-07-16 Armin Küper , Robert Dürr , Steffen Waldherr

Albeit worryingly underrated in the recent literature on machine learning in general (and, on deep learning in particular), multivariate density estimation is a fundamental task in many applications, at least implicitly, and still an open…

Neural and Evolutionary Computing · Computer Science 2020-12-08 Edmondo Trentin

Diagnostic testing provides a unique setting for studying and developing tools in classification theory. In such contexts, the concept of prevalence, i.e. the number of individuals with a given condition, is fundamental, both as an inherent…

Quantum Computing and especially Quantum Machine Learning, in a short period of time, has gained a lot of interest through research groups around the world. This can be seen in the increasing number of proposed models for pattern…

Quantum Physics · Physics 2020-12-23 Héctor Iván García Hernández , Raymundo Torres Ruiz , Guo-Hua Sun

To cluster data that are not linearly separable in the original feature space, $k$-means clustering was extended to the kernel version. However, the performance of kernel $k$-means clustering largely depends on the choice of kernel…

Machine Learning · Computer Science 2018-11-02 Yaqiang Yao , Huanhuan Chen

Real-time density estimation is ubiquitous in many applications, including computer vision and signal processing. Kernel density estimation is arguably one of the most commonly used density estimation techniques, and the use of "sliding…

Machine Learning · Statistics 2023-11-13 Yinsong Wang , Yu Ding , Shahin Shahrampour

Given points $p_1, \dots, p_n$ in $\mathbb{R}^d$, how do we find a point $x$ which maximizes $\frac{1}{n} \sum_{i=1}^n e^{-\|p_i - x\|^2}$? In other words, how do we find the maximizing point, or mode of a Gaussian kernel density estimation…

Data Structures and Algorithms · Computer Science 2019-12-18 Jasper C. H. Lee , Jerry Li , Christopher Musco , Jeff M. Phillips , Wai Ming Tai

In this paper, we introduce a robust nonparametric density estimator combining the popular Kernel Density Estimation method and the Median-of-Means principle (MoM-KDE). This estimator is shown to achieve robustness to any kind of anomalous…

Statistics Theory · Mathematics 2020-07-01 Pierre Humbert , Batiste Le Bars , Ludovic Minvielle , Nicolas Vayatis

In many statistical and econometric applications, we gather individual samples from various interconnected populations that undeniably exhibit common latent structures. Utilizing a model that incorporates these latent structures for such…

Methodology · Statistics 2023-09-19 Archer Gong Zhang , Jiahua Chen

Embedding probability distributions into reproducing kernel Hilbert spaces (RKHS) has enabled powerful nonparametric methods such as the maximum mean discrepancy (MMD), a statistical distance with strong theoretical and computational…

Machine Learning · Statistics 2025-05-28 Masha Naslidnyk , Siu Lun Chau , François-Xavier Briol , Krikamol Muandet

One-class Classification (OCC) is an area of machine learning which addresses prediction based on unbalanced datasets. Basically, OCC algorithms achieve training by means of a single class sample, with potentially some additional…

Machine Learning · Statistics 2020-03-27 Sarah Itani , Fabian Lecron , Philippe Fortemps

The Neural Autoregressive Distribution Estimator (NADE) and its real-valued version RNADE are competitive density models of multidimensional data across a variety of domains. These models use a fixed, arbitrary ordering of the data…

Machine Learning · Statistics 2014-01-14 Benigno Uria , Iain Murray , Hugo Larochelle

Distribution regression refers to the supervised learning problem where labels are only available for groups of inputs instead of individual inputs. In this paper, we develop a rigorous mathematical framework for distribution regression…

Machine Learning · Computer Science 2021-09-30 Maud Lemercier , Cristopher Salvi , Theodoros Damoulas , Edwin V. Bonilla , Terry Lyons

We consider the problem of making nonparametric inference in a class of multi-dimensional diffusions in divergence form, from low-frequency data. Statistical analysis in this setting is notoriously challenging due to the intractability of…

Methodology · Statistics 2025-01-23 Matteo Giordano , Sven Wang

Current meta-learning approaches focus on learning functional representations of relationships between variables, i.e. on estimating conditional expectations in regression. In many applications, however, we are faced with conditional…

Machine Learning · Statistics 2021-02-25 Jean-Francois Ton , Lucian Chan , Yee Whye Teh , Dino Sejdinovic

Class imbalance is a common challenge in real-world binary classification tasks, often leading to predictions biased toward the majority class and reduced recognition of the minority class. This issue is particularly critical in domains…

Machine Learning · Computer Science 2025-10-07 Kotaro J. Nishimura , Yuichi Sakumura , Kazushi Ikeda

Quantum computing, with its potential to enhance various machine learning tasks, allows significant advancements in kernel calculation and model precision. Utilizing the one-class Support Vector Machine alongside a quantum kernel, known for…

Deep neural network (DNN) classifiers are often overconfident, producing miscalibrated class probabilities. In high-risk applications like healthcare, practitioners require $\textit{fully calibrated}$ probability predictions for…

Machine Learning · Statistics 2022-12-09 Zhen Lin , Shubhendu Trivedi , Jimeng Sun

This paper presents an intuitive application of multivariate kernel density estimation (KDE) for data correction. The method utilizes the expected value of the conditional probability density function (PDF) and a credible interval to…

Applications · Statistics 2025-09-19 Hai Bui , Mostafa Bakhoday-Paskyabi

This paper studies Kernel Density Estimation for a high-dimensional distribution $\rho(x)$. Traditional approaches have focused on the limit of large number of data points $n$ and fixed dimension $d$. We analyze instead the regime where…

Machine Learning · Computer Science 2024-10-21 Giulio Biroli , Marc Mézard