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In the missing data literature, the Maximum Likelihood Estimator (MLE) is celebrated for its ignorability property under missing at random (MAR) data. However, its sensitivity to misspecification of the (complete) data model, even under…

Methodology · Statistics 2025-09-23 Badr-Eddine Chérief-Abdellatif , Jeffrey Näf

For a multinomial distribution, suppose that we have prior knowledge of the sum of the probabilities of some categories. This allows us to construct a submodel in a full (i.e., no-restriction) model. Maximum likelihood estimation (MLE)…

Statistics Theory · Mathematics 2021-06-07 Yo Sheena

Maximum likelihood or restricted maximum likelihood (REML) estimates of the parameters in linear mixed-effects models can be determined using the lmer function in the lme4 package for R. As for most model-fitting functions in R, the model…

Computation · Statistics 2014-06-24 Douglas Bates , Martin Mächler , Ben Bolker , Steve Walker

Exact MLE for generalized linear mixed models (GLMMs) is a long-standing problem unsolved until today. The proposed research solves the problem. In this problem, the main difficulty is caused by intractable integrals in the likelihood…

Methodology · Statistics 2024-10-14 Tonglin Zhang

Mixture of Experts (MoE) are successful models for modeling heterogeneous data in many statistical learning problems including regression, clustering and classification. Generally fitted by maximum likelihood estimation via the well-known…

Machine Learning · Statistics 2018-10-30 Faicel Chamroukhi , Bao-Tuyen Huynh

Maximum likelihood estimation (MLE) of latent variable models is often recast as the minimization of a free energy functional over an extended space of parameters and probability distributions. This perspective was recently combined with…

Machine Learning · Computer Science 2024-06-05 Jen Ning Lim , Juan Kuntz , Samuel Power , Adam M. Johansen

Maximum likelihood estimation (MLE) methods are widely used for evolutionary tree. As evolutionary tree is not a smooth parameter, the consistency of its MLE has been a topic of debate. It has been noted without proof that the classical…

Populations and Evolution · Quantitative Biology 2014-05-06 Arindam RoyChoudhury

This paper develops several interesting, significant, and interconnected approaches to nonparametric or semi-parametric statistical inferences. The overwhelmingly favoured maximum likelihood estimator (MLE) under parametric model is…

Statistics Theory · Mathematics 2023-03-30 Haodi Liang , Jiahua Chen

Maximum likelihood estimation of linear functionals in the inverse problem of deconvolution is considered. Given observations of a random sample from a distribution $P_0\equiv P_{F_0}$ indexed by a (potentially infinite-dimensional)…

Statistics Theory · Mathematics 2019-02-05 Catia Scricciolo

A number of problems in quantum state and system identification are addressed. Specifically, it is shown that the maximum likelihood estimation (MLE) approach, already known to apply to quantum state tomography, is also applicable to…

Quantum Physics · Physics 2007-05-23 Robert Kosut , Ian A. Walmsley , Herschel Rabitz

A fundamental question in the field of molecular computation is what computational tasks a biochemical system can carry out. In this work, we focus on the problem of finding the maximum likelihood estimate (MLE) for log-affine models. We…

Molecular Networks · Quantitative Biology 2025-10-06 Oskar Henriksson , Carlos Améndola , Jose Israel Rodriguez , Polly Y. Yu

We consider a one dimensional sub-ballistic random walk evolving in a parametric i.i.d. random environment. We study the asymptotic properties of the maximum likelihood estimator (MLE) of the parameter based on a single observation of the…

Probability · Mathematics 2014-05-13 Mikael Falconnet , Dasha Loukianova , Arnaud Gloter

Histogram-based empirical Bayes methods developed for analyzing data for large numbers of genes, SNPs, or other biological features tend to have large biases when applied to data with a smaller number of features such as genes with…

Methodology · Statistics 2013-10-10 Marta Padilla , David R. Bickel

The asymptotic normality of the maximum likelihood estimator (MLE) under regularity conditions is a cornerstone of statistical theory. In this paper, we give explicit upper bounds on the distributional distance between the distribution of…

Statistics Theory · Mathematics 2018-07-23 Andreas Anastasiou

We consider the problem of estimating the distribution function, the density and the hazard rate of the (unobservable) event time in the current status model. A well studied and natural nonparametric estimator for the distribution function…

Statistics Theory · Mathematics 2010-01-13 Piet Groeneboom , Geurt Jongbloed , Birgit I. Witte

Maximum likelihood estimation (MLE) and heuristic predictive estimation (HPE) are two widely used approaches in industrial uncertainty analysis. We review them from the point of view of decision theory, using Bayesian inference as a gold…

Applications · Statistics 2010-09-23 Merlin Keller , Eric Parent , Alberto Pasanisi

As the maximum likelihood method is the most commonly used method for parameters estimation being unbiased, consistent, efficient, and asymptotically normal, MLE is used to fit the new distribution (MBUW). But in small to moderate sample…

Methodology · Statistics 2025-02-17 Iman Mohammed Attia

This paper develops a unified estimation framework, the Maximum Ideal Likelihood Estimation (MILE), for general parametric models with latent variables. Unlike traditional approaches relying on the marginal likelihood of the observed data,…

Statistics Theory · Mathematics 2025-10-08 Yizhou Cai , Ting Fung Ma

Empirical economic research frequently applies maximum likelihood estimation in cases where the likelihood function is analytically intractable. Most of the theoretical literature focuses on maximum simulated likelihood (MSL) estimators,…

Econometrics · Economics 2019-08-13 Michael Griebel , Florian Heiss , Jens Oettershagen , Constantin Weiser

Fisher's Method of Maximum Likelihood is shown to be a procedure for the construction of likelihood intervals or regions, instead of a procedure of point estimation. Based on Fisher's articles and books it is justified that by estimation…

Statistics Theory · Mathematics 2008-07-23 Esa Uusipaikka