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This paper presents a comprehensive systematic review of generative models (GANs, VAEs, DMs, and LLMs) used to synthesize various medical data types, including imaging (dermoscopic, mammographic, ultrasound, CT, MRI, and X-ray), text,…

Generative adversarial networks or GANs are a type of generative modeling framework. GANs involve a pair of neural networks engaged in a competition in iteratively creating fake data, indistinguishable from the real data. One notable…

Machine learning-assisted diagnosis shows promise, yet medical imaging datasets are often scarce, imbalanced, and constrained by privacy, making data augmentation essential. Classical generative models typically demand extensive…

This work introduces SkinGenBench, a systematic biomedical imaging benchmark that investigates how preprocessing complexity interacts with generative model choice for synthetic dermoscopic image augmentation and downstream melanoma…

Privacy concerns around sharing personally identifiable information are a major practical barrier to data sharing in medical research. However, in many cases, researchers have no interest in a particular individual's information but rather…

Publicly available diabetic retinopathy (DR) datasets are imbalanced, containing limited numbers of images with DR. This imbalance contributes to overfitting when training machine learning classifiers. The impact of this imbalance is…

Despite the recent success in applying supervised deep learning to medical imaging tasks, the problem of obtaining large and diverse expert-annotated datasets required for the development of high performant models remains particularly…

Biomedical research increasingly relies on integrating diverse data modalities, including gene expression profiles, medical images, and clinical metadata. While medical images and clinical metadata are routinely collected in clinical…

Imbalanced image datasets are commonly available in the domain of biomedical image analysis. Biomedical images contain diversified features that are significant in predicting targeted diseases. Generative Adversarial Networks (GANs) are…

Convolutional Neural Networks (CNNs) can play a key role in Medical Image Analysis under large-scale annotated datasets. However, preparing such massive dataset is demanding. In this context, Generative Adversarial Networks (GANs) can…

While hundreds of artificial intelligence (AI) algorithms are now approved or cleared by the US Food and Drugs Administration (FDA), many studies have shown inconsistent generalization or latent bias, particularly for underrepresented…

Analyzing medical data to find abnormalities is a time-consuming and costly task, particularly for rare abnormalities, requiring tremendous efforts from medical experts. Artificial intelligence has become a popular tool for the automatic…

Generative models have been applied in the medical imaging domain for various image recognition and synthesis tasks. However, a more controllable and interpretable image synthesis model is still lacking yet necessary for important…

Synthetic data generation is an important application of machine learning in the field of medical imaging. While existing approaches have successfully applied fine-tuned diffusion models for synthesizing medical images, we explore potential…

The ability to generate synthetic medical images is useful for data augmentation, domain transfer, and out-of-distribution detection. However, generating realistic, high-resolution medical images is challenging, particularly for Full Field…

In the field of computer vision, multimodal image generation has become a research hotspot, especially the task of integrating text, image, and style. In this study, we propose a multimodal image generation method based on Generative…

Despite an impressive performance from the latest GAN for generating hyper-realistic images, GAN discriminators have difficulty evaluating the quality of an individual generated sample. This is because the task of evaluating the quality of…

The development of accurate medical image classification models is often constrained by privacy concerns and data scarcity for certain conditions, leading to small and imbalanced datasets. To address these limitations, this study explores…

Generative artificial intelligence (AI) is rapidly transforming medical imaging by enabling capabilities such as data synthesis, image enhancement, modality translation, and spatiotemporal modeling. This review presents a comprehensive and…

In biomedical image analysis, the applicability of deep learning methods is directly impacted by the quantity of image data available. This is due to deep learning models requiring large image datasets to provide high-level performance.…