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Virtual interventions enable the physics-based simulation of device deployment within coronary arteries. This framework allows for counterfactual reasoning by deploying the same device in different arterial anatomies. However, current…

Image and Video Processing · Electrical Eng. & Systems 2025-11-26 Karim Kadry , Shreya Gupta , Jonas Sogbadji , Michiel Schaap , Kersten Petersen , Takuya Mizukami , Carlos Collet , Farhad R. Nezami , Elazer R. Edelman

Diffusion models have recently gained immense interest for their generative capabilities, specifically the high quality and diversity of the synthesized data. However, examples of their applications in 3D medical imaging are still scarce,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-21 Jolanta Mozyrska , Marcel Beetz , Luke Melas-Kyriazi , Vicente Grau , Abhirup Banerjee , Alfonso Bueno-Orovio

A digital twin is a virtual replica of a real-world physical phenomena that uses mathematical modeling to characterize and simulate its defining features. By constructing digital twins for disease processes, we can perform in-silico…

Machine Learning · Computer Science 2024-11-04 Keying Kuang , Frances Dean , Jack B. Jedlicki , David Ouyang , Anthony Philippakis , David Sontag , Ahmed M. Alaa

Magnetic resonance (MR) imaging, including cardiac MR, is prone to domain shift due to variations in imaging devices and acquisition protocols. This challenge limits the deployment of trained AI models in real-world scenarios, where…

Computer Vision and Pattern Recognition · Computer Science 2025-08-11 Xin Ci Wong , Duygu Sarikaya , Kieran Zucker , Marc De Kamps , Nishant Ravikumar

In medical imaging, the diffusion models have shown great potential for synthetic image generation tasks. However, these approaches often lack the interpretable connections between the generated and real images and can create anatomically…

Image and Video Processing · Electrical Eng. & Systems 2026-02-12 Jian-Qing Zheng , Yuanhan Mo , Yang Sun , Jiahua Li , Fuping Wu , Ziyang Wang , Tonia Vincent , Bartłomiej W. Papież

Scaling by training on large datasets has been shown to enhance the quality and fidelity of image generation and manipulation with diffusion models; however, such large datasets are not always accessible in medical imaging due to cost and…

Computer Vision and Pattern Recognition · Computer Science 2025-04-14 Yousef Yeganeh , Azade Farshad , Ioannis Charisiadis , Marta Hasny , Martin Hartenberger , Björn Ommer , Nassir Navab , Ehsan Adeli

Diffusion models (DMs) are one of the most widely used generative models for producing high quality images. However, a flurry of recent papers points out that DMs are least private forms of image generators, by extracting a significant…

Machine Learning · Statistics 2025-03-06 Michael F. Liu , Saiyue Lyu , Margarita Vinaroz , Mijung Park

Temporal volume images with 3D+t (4D) information are often used in medical imaging to statistically analyze temporal dynamics or capture disease progression. Although deep-learning-based generative models for natural images have been…

Image and Video Processing · Electrical Eng. & Systems 2022-06-28 Boah Kim , Jong Chul Ye

Generative models are becoming popular for the synthesis of medical images. Recently, neural diffusion models have demonstrated the potential to generate photo-realistic images of objects. However, their potential to generate medical images…

Image and Video Processing · Electrical Eng. & Systems 2022-11-03 Hazrat Ali , Shafaq Murad , Zubair Shah

Latent diffusion models (LDMs) have recently achieved strong performance in 3D medical image synthesis. However, modalities like cine cardiac MRI (CMR), representing a temporally synchronized 3D volume across the cardiac cycle, add an…

Accurately modeling the spatiotemporal evolution of tumor morphology from baseline imaging is a pre-requisite for developing digital twin frameworks that can simulate disease progression and treatment response. Most existing approaches…

Image and Video Processing · Electrical Eng. & Systems 2025-10-01 Moinak Bhattacharya , Gagandeep Singh , Prateek Prasanna

Serving as an emerging and powerful tool, Large Language Model (LLM)-driven Human Digital Twins are showing great potential in healthcare system research. However, its actual simulation ability for complex human psychological traits, such…

Human-Computer Interaction · Computer Science 2025-12-11 Yuzhou Wu , Mingyang Wu , Di Liu , Rong Yin , Kang Li

The diffusion model has recently emerged as a potent approach in computer vision, demonstrating remarkable performances in the field of generative artificial intelligence. Capable of producing high-quality synthetic images, diffusion models…

Image and Video Processing · Electrical Eng. & Systems 2025-05-14 Abdullah , Tao Huang , Ickjai Lee , Euijoon Ahn

Diabetic Foot Ulcer (DFU) is a serious skin wound requiring specialized care. However, real DFU datasets are limited, hindering clinical training and research activities. In recent years, generative adversarial networks and diffusion models…

Image and Video Processing · Electrical Eng. & Systems 2023-11-01 Reza Basiri , Karim Manji , Francois Harton , Alisha Poonja , Milos R. Popovic , Shehroz S. Khan

Digital twin technology has is anticipated to transform healthcare, enabling personalized medicines and support, earlier diagnoses, simulated treatment outcomes, and optimized surgical plans. Digital twins are readily gaining traction in…

Machine Learning · Computer Science 2023-07-12 Logan Nye

Diffusion models (DMs) have emerged as powerful foundation models for a variety of tasks, with a large focus in synthetic image generation. However, their requirement of large annotated datasets for training limits their applicability in…

Computer Vision and Pattern Recognition · Computer Science 2024-07-17 Guillermo Jimenez-Perez , Pedro Osorio , Josef Cersovsky , Javier Montalt-Tordera , Jens Hooge , Steffen Vogler , Sadegh Mohammadi

The tremendous progress in neural image generation, coupled with the emergence of seemingly omnipotent vision-language models has finally enabled text-based interfaces for creating and editing images. Handling generic images requires a…

Computer Vision and Pattern Recognition · Computer Science 2023-07-27 Omri Avrahami , Ohad Fried , Dani Lischinski

We investigate the utility of diffusion generative models to efficiently synthesise datasets that effectively train deep learning models for image analysis. Specifically, we propose novel $\Gamma$-distribution Latent Denoising Diffusion…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 David Stojanovski , Mariana da Silva , Pablo Lamata , Arian Beqiri , Alberto Gomez

Data scarcity in medical imaging poses significant challenges due to privacy concerns. Diffusion models, a recent generative modeling technique, offer a potential solution by generating synthetic and realistic data. However, questions…

Image and Video Processing · Electrical Eng. & Systems 2024-12-24 Abdullah al Nomaan Nafi , Md. Alamgir Hossain , Rakib Hossain Rifat , Md Mahabub Uz Zaman , Md Manjurul Ahsan , Shivakumar Raman

Diffusion models have revolutionized image generation, yet several challenges restrict their application to large-image domains, such as digital pathology and satellite imagery. Given that it is infeasible to directly train a model on…

Computer Vision and Pattern Recognition · Computer Science 2025-03-26 Srikar Yellapragada , Alexandros Graikos , Kostas Triaridis , Prateek Prasanna , Rajarsi R. Gupta , Joel Saltz , Dimitris Samaras
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