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Quantifying the degree of atrophy is done clinically by neuroradiologists following established visual rating scales. For these assessments to be reliable the rater requires substantial training and experience, and even then the rating…
Quantification of brain atrophy currently requires visual rating scales which are time consuming and automated brain image analysis is warranted. We validated our automated deep learning (DL) tool measuring the Global Cerebral Atrophy (GCA)…
Automated optic disc (OD) and optic cup (OC) segmentation in fundus images is relevant to efficiently measure the vertical cup-to-disc ratio (vCDR), a biomarker commonly used in ophthalmology to determine the degree of glaucomatous optic…
Assessing the severity of rheumatoid arthritis (RA) using the Total Sharp/Van Der Heijde Score (TSS) is crucial, but manual scoring is often time-consuming and subjective. This study introduces an Automated Radiographic Sharp Scoring…
Introduction: Bone health disorders like osteoarthritis and osteoporosis pose major global health challenges, often leading to delayed diagnoses due to limited diagnostic tools. This study presents an AI-powered system that analyzes knee…
Background: Invasive coronary arteriography (ICA) is recognized as the gold standard for diagnosing cardiovascular diseases, including unstable angina (UA). The challenge lies in determining the optimal timing for ICA in UA patients,…
Diabetic retinopathy (DR) is a complication of diabetes, and one of the major causes of vision impairment in the global population. As the early-stage manifestation of DR is usually very mild and hard to detect, an accurate diagnosis via…
Audio event classification has recently emerged as a promising approach in medical applications. In total hip arthroplasty (THA), intra-operative hammering acoustics provide critical cues for assessing the initial stability of the femoral…
Purpose: To examine whether incorporating anatomical awareness into a deep learning model can improve generalizability and enable prediction of disease progression. Methods: This retrospective multicenter study included conventional pelvic…
Osteosarcoma (OS) is an aggressive primary bone malignancy. Accurate histopathological assessment of viable versus non-viable tumor regions after neoadjuvant chemotherapy is critical for prognosis and treatment planning, yet manual…
Coronary CT angiography (CCTA) has established its role as a non-invasive modality for the diagnosis of coronary artery disease (CAD). The CAD-Reporting and Data System (CAD-RADS) has been developed to standardize communication and aid in…
Fractures, particularly in the distal forearm, are among the most common injuries in children and adolescents, with approximately 800 000 cases treated annually in Germany. The AO/OTA system provides a structured fracture type…
Parkinsons disease, PD, is a chronic condition that affects motor skills and includes symptoms like tremors and rigidity. The current diagnostic procedure uses patient assessments to evaluate symptoms and sometimes a magnetic resonance…
Incomplete Hippocampal Inversion (IHI), sometimes called hippocampal malrotation, is an atypical anatomical pattern of the hippocampus found in about 20% of the general population. IHI can be visually assessed on coronal slices of T1…
Knee osteoarthritis frequently exhibits discordance between structural damage observed in imaging and patient-reported symptoms such as pain. This mismatch complicates clinical interpretation and patient stratification and remains…
Recent advancements in computer vision promise to automate medical image analysis. Rheumatoid arthritis is an autoimmune disease that would profit from computer-based diagnosis, as there are no direct markers known, and doctors have to rely…
Invasive Coronary Angiography (ICA) images are considered the gold standard for assessing the state of the coronary arteries. Deep learning classification methods are widely used and well-developed in different areas where medical imaging…
Radiographic knee alignment (KA) measurement is important for predicting joint health and surgical outcomes after total knee replacement. Traditional methods for KA measurements are manual, time-consuming and require long-leg radiographs.…
Longitudinal assessment of brain atrophy, particularly in the hippocampus, is a well-studied biomarker for neurodegenerative diseases, such as Alzheimer's disease (AD). In clinical trials, estimation of brain progressive rates can be…
Osteoarthritis (OA) is one of the major health issues among the elderly population. MRI is the most popular technology to observe and evaluate the progress of OA course. However, the extreme labor cost of MRI analysis makes the process…