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Whole genome sequencing (WGS) is quickly becoming the customary means for identification of antimicrobial resistance (AMR) due to its ability to obtain high resolution information about the genes and mechanisms that are causing resistance…

Genomics · Quantitative Biology 2021-07-27 Mattia Prosperi , Simone Marini , Christina Boucher , Jiang Bian

This paper is Part II of a two-part series devoting to the study of systematic measures in a complex bio-network modeled by a system of ordinary differential equations. In this part, we quantify several systematic measures of a biological…

Probability · Mathematics 2016-06-13 Yao Li , Yingfei Yi

Mass-action chemical reaction systems are frequently used in Computational Biology. The corresponding polynomial dynamical systems are often large (consisting of tens or even hundreds of ordinary differential equations) and poorly…

Dynamical Systems · Mathematics 2011-07-13 Mercedes Perez Millan , Alicia Dickenstein , Anne Shiu , Carsten Conradi

Finding out universal conditions describing the freeze-out parameters was a subject of various phenomenological studies. In the present work, we introduce a new condition based on constant trace anomaly (or interaction measure) calculated…

High Energy Physics - Phenomenology · Physics 2013-09-23 A. Tawfik

Over the past decade, adversarial training has emerged as one of the few reliable methods for enhancing model robustness against adversarial attacks [Szegedy et al., 2014, Madry et al., 2018, Xhonneux et al., 2024], while many alternative…

Cryptography and Security · Computer Science 2024-08-05 Leo Schwinn , Simon Geisler

Background: Many biological systems are modeled qualitatively with discrete models, such as probabilistic Boolean networks, logical models, Petri nets, and agent-based models, with the goal to gain a better understanding of the system. The…

Generalized Chinese Remainder Theorem (CRT) has been shown to be a powerful approach to solve the ambiguity resolution problem. However, with its close relationship to number theory, study in this area is mainly from a coding theory…

Machine Learning · Statistics 2018-11-29 Nan Du , Zhikang Wang , Hanshen Xiao

Equations of motion that recognize biochemical patterns are described. The equations are partial differential equations in a continuous multiple component system in which adequate initial and boundary conditions are given. The biochemical…

Biological Physics · Physics 2010-03-25 Eisuke Chikayama

Resilience characterizes a system's ability to retain its original function when perturbations happen. In the past years our attention mainly focused on small-scale resilience, yet our understanding of resilience in large-scale network…

Adaptation and Self-Organizing Systems · Physics 2020-10-13 Mengbang Zou , Luca Zanotti Fragonara , Weisi Guo

As human activities intensify, environmental systems such as aquatic ecosystems and water treatment systems face increasingly complex pressures, impacting ecological balance, public health, and sustainable development, making intelligent…

Machine Learning · Computer Science 2025-03-13 Lei Liu , Yuchao Lu , Ling An , Huajie Liang , Chichun Zhou , Zhenyu Zhang

Angle-resolved photoemission spectroscopy (ARPES) measures the single-particle excitations of a many-body quantum system with both energy and momentum resolution, providing detailed information about strongly interacting materials. ARPES is…

In machine learning, no data point stands alone. We believe that context is an underappreciated concept in many machine learning methods. We propose Attention-Based Clustering (ABC), a neural architecture based on the attention mechanism,…

Machine Learning · Computer Science 2020-10-05 Samuel Coward , Erik Visse-Martindale , Chithrupa Ramesh

In a recent paper it was shown that, for chemical reaction networks possessing a subtle structural property called concordance, dynamical behavior of a very circumscribed (and largely stable) kind is enforced, so long as the kinetics lies…

Molecular Networks · Quantitative Biology 2012-04-26 Guy Shinar , Martin Feinberg

Data replication is used in distributed systems to maintain up-to-date copies of shared data across multiple computers in a network. However, despite decades of research, algorithms for achieving consistency in replicated systems are still…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-08-30 Victor B. F. Gomes , Martin Kleppmann , Dominic P. Mulligan , Alastair R. Beresford

Persistence is an important characteristic of many complex systems in nature, related to how long the system remains at a certain state before changing to a different one. The study of complex systems' persistence involves different…

Dynamical Systems · Mathematics 2022-05-05 S. Salcedo-Sanz , D. Casillas-Pérez , J. Del Ser , C. Casanova-Mateo , L. Cuadra , M. Piles , G. Camps-Valls

The detailed balance property is a fundamental property that must be satisfied in all the macroscopic systems with a well defined temperature at each point. On the other hand, many biochemical networks work in non-equilibrium conditions and…

Classical Analysis and ODEs · Mathematics 2025-02-10 E. Franco , J. J. L. Velázquez

Randomized Smoothing (RS) is considered the state-of-the-art approach to obtain certifiably robust models for challenging tasks. However, current RS approaches drastically decrease standard accuracy on unperturbed data, severely limiting…

Machine Learning · Computer Science 2022-04-04 Miklós Z. Horváth , Mark Niklas Müller , Marc Fischer , Martin Vechev

A range of defense methods have been proposed to improve the robustness of neural networks on adversarial examples, among which provable defense methods have been demonstrated to be effective to train neural networks that are certifiably…

Machine Learning · Computer Science 2021-01-21 Mengting Xu , Tao Zhang , Zhongnian Li , Daoqiang Zhang

Chemical reaction networks (CRNs) formally model chemistry in a well-mixed solution. CRNs are widely used to describe information processing occurring in natural cellular regulatory networks, and with upcoming advances in synthetic biology,…

Computational Complexity · Computer Science 2013-04-17 David Doty

Based on the generalized Routh-Hurwitz criterion, we propose a sufficient and necessary criterion for testing the stability of fractional-order linear systems with order {\alpha}{\in}[1,2), called the fractional-order Routh-Hurwitz…

Dynamical Systems · Mathematics 2022-02-22 Jing Yang , Xiaorong Hou , Yajun Li