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The human nose exhibits a huge variation in shape among individuals. All these variants alter the airflow through the nasal cavity and can impact how we smell odors. To acquire a better understanding of physiological and pathological…

The parameterization of open and closed anatomical surfaces is of fundamental importance in many biomedical applications. Spherical harmonics, a set of basis functions defined on the unit sphere, are widely used for anatomical shape…

Computational Geometry · Computer Science 2022-06-30 Gary P. T. Choi , Amita Giri , Lalan Kumar

Anatomical shape analysis plays a pivotal role in clinical research and hypothesis testing, where the relationship between form and function is paramount. Correspondence-based statistical shape modeling (SSM) facilitates population-level…

Computer Vision and Pattern Recognition · Computer Science 2024-05-17 Jadie Adams , Krithika Iyer , Shireen Elhabian

Statistical shape modeling (SSM) enables population-based quantitative analysis of anatomical shapes, informing clinical diagnosis. Deep learning approaches predict correspondence-based SSM directly from unsegmented 3D images but require…

Computer Vision and Pattern Recognition · Computer Science 2023-07-21 Jadie Adams , Shireen Elhabian

The classification of shapes is of great interest in diverse areas ranging from medical imaging to computer vision and beyond. While many statistical frameworks have been developed for the classification problem, most are strongly tied to…

Machine Learning · Statistics 2019-01-24 Min Ho Cho , Sebastian Kurtek , Steven N. MacEachern

We propose a new shape analysis approach based on the non-local analysis of local shape variations. Our method relies on a novel description of shape variations, called Local Probing Field (LPF), which describes how a local probing operator…

Computational Geometry · Computer Science 2017-11-03 Julie Digne , Sébastien Valette , Raphaëlle Chaine

To date, the comparison of Statistical Shape Models (SSMs) is often solely performance-based, carried out by means of simplistic metrics such as compactness, generalization, or specificity. Any similarities or differences between the actual…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Maximilian Weiherer , Finn Klein , Bernhard Egger

Model reduction of large nonlinear systems often involves the projection of the governing equations onto linear subspaces spanned by carefully-selected modes. The criteria to select the modes relevant for reduction are usually…

Dynamical Systems · Mathematics 2021-03-18 Gergely Buza , Shobhit Jain , George Haller

Fragment-based shape signature techniques have proven to be powerful tools for computer-aided drug design. They allow scientists to search for target molecules with some similarity to a known active compound. They do not require reference…

Artificial Intelligence · Computer Science 2022-01-05 Thierry Petit , Randy J. Zauhar

Shape optimization models with one or more shapes are considered in this chapter. Of particular interest for applications are problems in which where a so-called shape functional is constrained by a partial differential equation (PDE)…

Optimization and Control · Mathematics 2021-07-19 Caroline Geiersbach , Estefania Loayza-Romero , Kathrin Welker

We present a general numerical approach to shape optimization with state constraints for 2-dimensional geometries, without relaxing the constraints. To do this we reformulate the problem on a fixed reference domain using a conformal…

Optimization and Control · Mathematics 2014-12-16 Christian Leithäuser , René Pinnau , Robert Feßler

The study of physiology demonstrates that the form (shape)of anatomical structures dictates their functions, and analyzing the form of anatomies plays a crucial role in clinical research. Statistical shape modeling (SSM) is a widely used…

Computer Vision and Pattern Recognition · Computer Science 2024-07-03 Krithika Iyer , Shireen Y. Elhabian

Piecewise Linear-Quadratic (PLQ) penalties are widely used to develop models in statistical inference, signal processing, and machine learning. Common examples of PLQ penalties include least squares, Huber, Vapnik, 1-norm, and their…

Machine Learning · Statistics 2021-01-01 Peng Zheng , Aleksandr Y. Aravkin , Karthikeyan Natesan Ramamurthy

We introduce a method called multi-scale local shape analysis, or MLSA, for extracting features that describe the local structure of points within a dataset. The method uses both geometric and topological features at multiple levels of…

Computational Geometry · Computer Science 2014-10-14 Paul Bendich , Ellen Gasparovic , John Harer , Rauf Izmailov , Linda Ness

Despite progress in the rapidly developing field of geometric deep learning, performing statistical analysis on geometric data--where each observation is a shape such as a curve, graph, or surface--remains challenging due to the…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Emmanuel Hartman , Nicolas Charon

Sparse additive modeling is a class of effective methods for performing high-dimensional nonparametric regression. In this work we show how shape constraints such as convexity/concavity and their extensions, can be integrated into additive…

Machine Learning · Computer Science 2017-05-03 Junming Yin , Yaoliang Yu

Identification of regions of interest (ROI) associated with certain disease has a great impact on public health. Imposing sparsity of pixel values and extracting active regions simultaneously greatly complicate the image analysis. We…

Machine Learning · Statistics 2016-05-30 Yao Chen , Xiao Wang , Linglong Kong , Hongtu Zhu

Many standard structural quantities, such as order parameters and correlation functions, exist for common condensed matter systems, such as spherical and rod-like particles. However, these structural quantities are often insufficient for…

Soft Condensed Matter · Physics 2012-01-18 Aaron S. Keys , Christopher R. Iacovella , Sharon C. Glotzer

This article describes a volumetric approach for procedural shape modeling and a new Procedural Shape Modeling Language (PSML) that facilitates the specification of these models. PSML provides programmers the ability to describe shapes in…

Graphics · Computer Science 2021-03-23 Andrew Willis , Prashant Ganesh , Kyle Volle , Jincheng Zhang , Kevin Brink

Statistical Shape Models of faces and various body parts are heavily used in medical image analysis, computer vision and visualization. Whilst the field is well explored with many existing tools, all of them aim at experts, which limits…

Computer Vision and Pattern Recognition · Computer Science 2024-02-21 Maximilian Hahn , Bernhard Egger