English
Related papers

Related papers: Scale invariance in early embryonic development

200 papers

An ubiquitous property of biological sensory systems is adaptation: a step increase in stimulus triggers an initial change in a biochemical or physiological response, followed by a more gradual relaxation toward a basal, pre-stimulus level.…

Systems and Control · Computer Science 2015-06-04 Maja Skataric , Eduardo Sontag

Developmental processes in multicellular organisms occur far from equilibrium, yet produce complex patterns with astonishing reproducibility. We measure the precision and reproducibility of bilaterally symmetric fly wings across the natural…

Tissues and Organs · Quantitative Biology 2013-09-25 Laurent Abouchar , Mariela D. Petkova , Cynthia R. Steinhardt , Thomas Gregor

A population of complete subgraphs or cliques in a network evolving via duplication-divergence is considered. We find that a number of cliques of each size scales linearly with the size of the network. We also derive a clique population…

Molecular Networks · Quantitative Biology 2009-11-11 I. Ispolatov , P. L. Krapivsky , I. Mazo , A. Yuryev

We consider statistical patterns of variation in growth rates for over 400 species of breeding birds across North America surveyed from 1966 to 1998. We report two results. First, the standard deviation of population growth rates decays as…

Statistical Mechanics · Physics 2007-05-23 Timothy H. Keitt , Luis A. N. Amaral , Sergey V. Buldyrev , H. E. Stanley

Scale invariance has received very little attention in physics. Nevertheless, it provides a natural conceptual foundation for a relational understanding of the universe, where absolute size loses meaning and only dimensionless ratios retain…

History and Philosophy of Physics · Physics 2026-02-13 Maria I. R. Lourenço , Julian Barbour , Francisco S. N. Lobo

It is shown that an alternative approach for the characterization of growing branched patterns consists of the statistical analysis of frozen structures, which cannot be modified by further growth, that arise due to competitive processes…

Other Condensed Matter · Physics 2009-11-11 C. M. Horowitz , M. A. Pasquale , E. V. Albano , A. J. Arvia

The precise layout of gene expression patterns is a crucial step in development. Formation of a sharp boundary between high and low expression domains requires a genetic mechanism which is both sensitive and robust to fluctuations, a demand…

Molecular Networks · Quantitative Biology 2015-06-26 Erel Levine , Peter McHale , Herbert Levine

Among several quantitative invariants found in evolutionary genomics, one of the most striking is the scaling of the overall abundance of proteins, or protein domains, sharing a specific functional annotation across genomes of given size.…

Genomics · Quantitative Biology 2017-03-30 Eleonora de Lazzari , Jacopo Grilli , Sergei Maslov , Marco Cosentino Lagomarsino

Real-world road networks have an approximate scale-invariance property; can one devise mathematical models of random networks whose distributions are {\em exactly} invariant under Euclidean scaling? This requires working in the continuum…

Probability · Mathematics 2015-06-04 David J. Aldous

One of the classical questions in evolutionary biology is how evolutionary processes are coupled at the gene and species level. With this motivation, we compare the topological properties (mainly the depth scaling, as a characterization of…

Populations and Evolution · Quantitative Biology 2011-07-26 E. Alejandro Herrada , Víctor M. Eguíluz , Emilio Hernández-García , Carlos M. Duarte

Using a simple model with link removals as well as link additions, we show that an evolving network is scale free with a degree exponent in the range of (2, 4]. We then establish a relation between the network evolution and a set of…

Mathematical Physics · Physics 2007-05-23 Dinghua Shi , Liming Liu , Xiang Zhu , Huijie Zhou , Binbin Wang

Understanding the patterns and processes of diversification of life in the planet is a key challenge of science. The Tree of Life represents such diversification processes through the evolutionary relationships among the different taxa, and…

Populations and Evolution · Quantitative Biology 2011-06-16 E. Alejandro Herrada , Claudio J. Tessone , Konstantin Klemm , Victor M. Eguiluz , Emilio Hernandez-Garcia , Carlos M. Duarte

Real-world growth processes and scalings have been broadly categorized into three growth regimes with distinctly different properties and driving forces. The first two are characterized by a positive and constant feedback between growth and…

Physics and Society · Physics 2025-03-20 Alain Govaert , André Teixeira , Emma Tegling

In this paper we introduce a model of spatial network growth in which nodes are placed at randomly selected locations on a unit square in $\mathbb{R}^2$, forming new connections to old nodes subject to the constraint that edges do not…

Physics and Society · Physics 2016-02-12 Garvin Haslett , Seth Bullock , Markus Brede

Morphogen profiles play a vital role in biology by specifying position in embryonic development. However, the factors that influence the shape of a morphogen profile remain poorly understood. Since morphogens should provide precise…

Molecular Networks · Quantitative Biology 2009-11-27 Timothy E Saunders , Martin Howard

With the number of sequenced genomes now over one hundred, and the availability of rough functional annotations for a substantial proportion of their genes, it has become possible to study the statistics of gene content across genomes. Here…

Biological Physics · Physics 2007-05-23 Erik van Nimwegen

We develop a simple computational model for cell boundary evolution in plastic deformation. We study the cell boundary size distribution and cell boundary misorientation distribution that experimentally have been found to have scaling forms…

Materials Science · Physics 2013-05-29 James P. Sethna , Valerie R. Coffman , Eugene Demler

The physical origins of the Fundamental Plane (FP) scaling relations are investigated for early-type galaxies observed at optical and near-infrared wavelengths. The slope for the FP is shown to increase systematically with wavelength from…

Astrophysics · Physics 2009-10-30 M. A. Pahre , R. R. de Carvalho , S. G. Djorgovski

We demonstrate that scale-free patterns are observed in a spatially extended stochastic system whose deterministic part undergoes a saddle-node bifurcation. Remarkably, the scale-free patterns appear only at a particular time in relaxation…

Statistical Mechanics · Physics 2008-11-15 Mami Iwata , Shin-ichi Sasa

During embryonic development, a spatial pattern is formed in which proportions are established precisely. As an early pattern formation step in Drosophila embryos, an anterior-posterior gradient of Bicoid (Bcd) induces hunchback (hb)…

Cell Behavior · Quantitative Biology 2007-05-23 Tinri Aegerter-Wilmsen , Christof M. Aegerter , Ton Bisseling