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We analyze a class of cell-bulk coupled PDE-ODE models, motivated by quorum and diffusion sensing phenomena in microbial systems, that characterize communication between localized spatially segregated dynamically active signaling…

Pattern Formation and Solitons · Physics 2020-07-20 Sarafa A. Iyaniwura , Michael J. Ward

Using a stochastic generalization of the Hodgkin–Huxley model, we consider the influence of intrinsic channel noise on the synchronization between the spiking activity of the excitable membrane and an externally applied periodic…

Biological Physics · Physics 2007-05-23 Gerhard Schmid , Igor Goychuk , Peter Hanggi

We observed the scintillation pattern of nine bright pulsars at 324 MHz and three at 1.68 GHz and analyzed the wavenumber spectrum which is related to electron density variations of the plasma turbulence of the interstellar medium. For all…

Astrophysics of Galaxies · Physics 2022-12-21 N. Bartel , M. S. Burgin , E. N. Fadeev , M. V. Popov , N. Ronaghikhameneh , T. V. Smirnova , V. A. Soglasnov

NF-kB is a major transcription factor mediating inflammatory response. In response to pro-inflammatory stimulus, it exhibits characteristic response -- a pulse followed by noisy oscillations in concentrations of considerably smaller…

Biological Physics · Physics 2013-02-07 Sirin W. Gangstad , Cilie W. Feldager , Jeppe Juul , Ala Trusina

Neuronal activity arises from an interaction between ongoing firing generated spontaneously by neural circuits and responses driven by external stimuli. Using mean-field analysis, we ask how a neural network that intrinsically generates…

Neurons and Cognition · Quantitative Biology 2010-08-04 Kanaka Rajan , L F Abbott , Haim Sompolinsky

The stability of the dynamical states characterized by a uniform firing rate ({\it splay states}) is analyzed in a network of globally coupled leaky integrate-and-fire neurons. This is done by reducing the set of differential equations to a…

Disordered Systems and Neural Networks · Physics 2007-11-27 Rüdiger Zillmer , Roberto Livi , Antonio Politi , Alessandro Torcini

Even in the steady-state, the number of biomolecules in living cells fluctuates dynamically; and the frequency spectrum of this chemical fluctuation carries valuable information about the mechanism and the dynamics of the intracellular…

Biological Physics · Physics 2018-08-21 Sanggeun Song , Gil-Suk Yang , Seong Jun Park , Ji-Hyun Kim , Jaeyoung Sung

We study the dynamics of intracellular calcium oscillations in the presence of proteins that bind calcium on multiple sites and that are generally believed to act as passive calcium buffers in cells. We find that multisite calcium-binding…

Subcellular Processes · Quantitative Biology 2015-05-14 Roberto Chignola , Alessio Del Fabbro , Edoardo Milotti

Vesicle-mediated secretion of ions or molecules is a central mechanism of cellular communication, for example in processes such as neurotransmission or hormone release. These events are inherently stochastic: vesicle fusions lead to bursts…

Statistical Mechanics · Physics 2026-05-08 Jan Hauke , Julian B. Voits , Ulrich S. Schwarz

Periodic neural activity not locked to the stimulus or to motor responses is usually ignored. Here, we present new tools for modeling and quantifying the information transmission based on periodic neural activity that occurs with…

Neurons and Cognition · Quantitative Biology 2008-12-05 Kilian Koepsell , Friedrich T. Sommer

Sample-to-sample fluctuations of the time-dependent conductance of a system with static disorder have been studied by means of diagrammatic theory and microwave pulsed transmission measurements. The fluctuations of time-dependent…

Mesoscale and Nanoscale Physics · Physics 2009-07-23 N. Cherroret , A. Pena , A. A. Chabanov , S. E. Skipetrov

The electrical properties of extracellular space around neurons are important to understand the genesis of extracellular potentials, as well as for localizing neuronal activity from extracellular recordings. However, the exact nature of…

We explore self-induced parametric coupling, also called internal resonances (IRs), in a membrane nanoelectromechanical system. Specifically, we focus on the formation of a limit cycle manifesting as a phononic frequency comb. Utilizing a…

Mesoscale and Nanoscale Physics · Physics 2025-08-08 Mengqi Fu , Orjan Ameye , Fan Yang , Jan Košata , Javier del Pino , Oded Zilberberg , Elke Scheer

Variability in neural responses is an ubiquitous phenomenon in neurons, usually modeled with stochastic differential equations. In particular, stochastic integrate-and-fire models are widely used to simplify theoretical studies. The…

Neurons and Cognition · Quantitative Biology 2009-06-12 Eugenio Urdapilleta , Ines Samengo

Noise aids the encoding of continuous signals into pulse sequences by way of stochastic resonance and endows the encoding device with a preferred frequency. We study encoding by a threshold device based on the Ornstein-Uhlenbeck process,…

Biological Physics · Physics 2007-05-23 Hans E. Plesser , Theo Geisel

Intracellular dynamics in living tissue are dominated by active transport driven by bioenergetic processes far from thermal equilibrium. Intracellular constituents typically execute persistent walks. In the limit of long mean-free paths,…

Quantitative Methods · Quantitative Biology 2019-04-12 Zhe Li , Hao Sun , John Turek , Shadia Jalal , Michael Childress , David D. Nolte

The activity of neurons within brain circuits has been ubiquitously reported to be correlated. The impact of these correlations on brain function has been extensively investigated. Correlations can in principle increase or decrease the…

Neurons and Cognition · Quantitative Biology 2025-07-24 Miguel Ibáñez-Berganza , Giulio Bondanelli , Stefano Panzeri

Synchronized oscillations in networks of inhibitory and excitatory coupled bursting neurons are common in a variety of neural systems from central pattern generators to human brain circuits. One example of the latter is the subcortical…

Neurons and Cognition · Quantitative Biology 2011-09-21 Choongseok Park , Leonid L. Rubchinsky

The cellular automaton (CA) pulsing model (arXiv:1806.06416) described the surprising phenomenon of spontaneous, sustained and robust rhythmic oscillations, pulsing dynamics, when random wiring is applied to a 2D `glider' rule running in a…

Cellular Automata and Lattice Gases · Physics 2021-03-02 Andrew Wuensche , Edward Coxon

We investigate multi-"photon" interband excitation processes in an optical lattice that is driven periodically in time by a modulation of the lattice depth. Assuming the system to be prepared in the lowest band, we compute the excitation…

Quantum Gases · Physics 2016-09-16 Christoph Sträter , André Eckardt
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