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The integration of multimodal Electronic Health Records (EHR) data has significantly improved clinical predictive capabilities. Leveraging clinical notes and multivariate time-series EHR, existing models often lack the medical context…

Artificial Intelligence · Computer Science 2024-02-13 Yinghao Zhu , Changyu Ren , Shiyun Xie , Shukai Liu , Hangyuan Ji , Zixiang Wang , Tao Sun , Long He , Zhoujun Li , Xi Zhu , Chengwei Pan

Although large language models (LLMs) have demonstrated impressive potential on simple tasks, their breadth of scope, lack of transparency, and insufficient controllability can make them less effective when assisting humans on more complex…

Human-Computer Interaction · Computer Science 2022-03-21 Tongshuang Wu , Michael Terry , Carrie J. Cai

Clinical language models are important for many applications in healthcare, but their development depends on access to extensive clinical text for pretraining. However, obtaining clinical notes from electronic health records (EHRs) at scale…

Computation and Language · Computer Science 2024-12-02 Jinghui Liu , Anthony Nguyen

Large Language Models (LLMs) have rapidly become important tools in Biomedical and Health Informatics (BHI), enabling new ways to analyze data, treat patients, and conduct research. This study aims to provide a comprehensive overview of LLM…

Digital Libraries · Computer Science 2024-07-30 Huizi Yu , Lizhou Fan , Lingyao Li , Jiayan Zhou , Zihui Ma , Lu Xian , Wenyue Hua , Sijia He , Mingyu Jin , Yongfeng Zhang , Ashvin Gandhi , Xin Ma

Electronic Health Records (EHRs) are pivotal in clinical practices, yet their retrieval remains a challenge mainly due to semantic gap issues. Recent advancements in dense retrieval offer promising solutions but existing models, both…

Information Retrieval · Computer Science 2025-07-25 Zhengyun Zhao , Huaiyuan Ying , Yue Zhong , Sheng Yu

The utilization of Electronic Health Records (EHRs) for clinical risk prediction is on the rise. However, strict privacy regulations limit access to comprehensive health records, making it challenging to apply standard machine learning…

Computation and Language · Computer Science 2023-12-08 Angeela Acharya , Sulabh Shrestha , Anyi Chen , Joseph Conte , Sanja Avramovic , Siddhartha Sikdar , Antonios Anastasopoulos , Sanmay Das

Electronic Health Records (EHRs) have become increasingly popular to support clinical decision-making and healthcare in recent decades. EHRs usually contain heterogeneous information, such as structural data in tabular form and unstructured…

Machine Learning · Computer Science 2024-03-15 Hejie Cui , Xinyu Fang , Ran Xu , Xuan Kan , Joyce C. Ho , Carl Yang

Clinical trial matching is the task of identifying trials for which patients may be potentially eligible. Typically, this task is labor-intensive and requires detailed verification of patient electronic health records (EHRs) against the…

Large language models (LLMs) have emerged as promising tools for assisting in medical tasks, yet processing Electronic Health Records (EHRs) presents unique challenges due to their longitudinal nature. While LLMs' capabilities to perform…

Artificial Intelligence · Computer Science 2025-03-07 Hejie Cui , Alyssa Unell , Bowen Chen , Jason Alan Fries , Emily Alsentzer , Sanmi Koyejo , Nigam Shah

Deep learning models exhibit state-of-the-art performance for many predictive healthcare tasks using electronic health records (EHR) data, but these models typically require training data volume that exceeds the capacity of most healthcare…

Machine Learning · Computer Science 2018-10-24 Edward Choi , Cao Xiao , Walter F. Stewart , Jimeng Sun

Clinical decision-making is inherently complex, often influenced by cognitive biases, incomplete information, and case ambiguity. Large Language Models (LLMs) have shown promise as tools for supporting clinical decision-making, yet their…

Machine Learning · Computer Science 2025-07-10 Burcu Sayin , Ipek Baris Schlicht , Ngoc Vo Hong , Sara Allievi , Jacopo Staiano , Pasquale Minervini , Andrea Passerini

Many diagnostic errors occur because clinicians cannot easily access relevant information in patient Electronic Health Records (EHRs). In this work we propose a method to use LLMs to identify pieces of evidence in patient EHR data that…

Pre-consultation is a critical component of effective healthcare delivery. However, generating comprehensive pre-consultation questionnaires from complex, voluminous Electronic Medical Records (EMRs) is a challenging task. Direct Large…

Artificial Intelligence · Computer Science 2025-08-04 Ruiqing Ding , Qianfang Sun , Yongkang Leng , Hui Yin , Xiaojian Li

In healthcare intelligence, the ability to fuse heterogeneous, multi-intent information from diverse clinical sources is fundamental to building reliable decision-making systems. Large Language Model (LLM)-driven information interaction…

Computation and Language · Computer Science 2025-07-04 Dingkang Yang , Jinjie Wei , Mingcheng Li , Jiyao Liu , Lihao Liu , Ming Hu , Junjun He , Yakun Ju , Wei Zhou , Yang Liu , Lihua Zhang

Large Language Models (LLMs) are transforming mental health care by enhancing accessibility, personalization, and efficiency in therapeutic interventions. These AI-driven tools empower mental health professionals with real-time support,…

Computers and Society · Computer Science 2025-01-22 Hari Mohan Pandey

Healthcare systems continuously generate vast amounts of electronic health records (EHRs), commonly stored in the Fast Healthcare Interoperability Resources (FHIR) standard. Despite the wealth of information in these records, their…

Computation and Language · Computer Science 2025-01-24 Sara Kothari , Ayush Gupta

Electronic medical records (EMRs) contain essential data for patient care and clinical research. With the diversity of structured and unstructured data in EHR, data visualization is an invaluable tool for managing and explaining these…

Databases · Computer Science 2025-06-17 Haodi Zhang , Siqi Ning , Qiyong Zheng , Jinyin Nie , Liangjie Zhang , Weicheng Wang , Yuanfeng Song

Electronic health records (EHRs) contain patients' heterogeneous data that are collected from medical providers involved in the patient's care, including medical notes, clinical events, laboratory test results, symptoms, and diagnoses. In…

Artificial Intelligence · Computer Science 2024-11-12 Shuai Niu , Yunya Song , Qing Yin , Yike Guo , Xian Yang

Large language models (LLMs) excel at text generation, but their ability to handle clinical classification tasks involving structured data, such as time series, remains underexplored. In this work, we adapt instruction-tuned LLMs using…

Computation and Language · Computer Science 2025-09-18 Iyadh Ben Cheikh Larbi , Ajay Madhavan Ravichandran , Aljoscha Burchardt , Roland Roller

Large language models (LLMs) hold promise for transforming healthcare, from streamlining administrative and clinical workflows to enriching patient engagement and advancing clinical decision-making. However, their successful integration…

Computers and Society · Computer Science 2025-04-04 Mohammed Al-Garadi , Tushar Mungle , Abdulaziz Ahmed , Abeed Sarker , Zhuqi Miao , Michael E. Matheny