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Paramagnetic rim lesions (PRLs) are an emerging biomarker in multiple sclerosis (MS). Manual identification and rim segmentation of PRLs on quantitative susceptibility mapping (QSM) images are time-consuming. Deep learning-based QSM-RimNet…
The automated detection of cortical lesions (CLs) in patients with multiple sclerosis (MS) is a challenging task that, despite its clinical relevance, has received very little attention. Accurate detection of the small and scarce lesions…
Quantitative susceptibility maps from magnetic resonance images can provide both prognostic and diagnostic information in multiple sclerosis, a neurodegenerative disease characterized by the formation of lesions in white matter brain…
Brain lesion volume measured on T2 weighted MRI images is a clinically important disease marker in multiple sclerosis (MS). Manual delineation of MS lesions is a time-consuming and highly operator-dependent task, which is influenced by…
Introduction: Multiple Sclerosis (MS) is a chronic disease that affects millions of people across the globe. MS can critically affect different organs of the central nervous system such as the eyes, the spinal cord, and the brain.…
Background: Accurate lesion segmentation is critical for multiple sclerosis (MS) diagnosis, yet current deep learning approaches face robustness challenges. Aim: This study improves MS lesion segmentation by combining data fusion and deep…
Quantitative susceptibility mapping (QSM) is an MRI phase-based post-processing method that quantifies tissue magnetic susceptibility distributions. However, QSM acquisitions are relatively slow, even with parallel imaging. Incoherent…
Recently, deep neural network-powered quantitative susceptibility mapping (QSM), QSMnet, successfully performed ill conditioned dipole inversion in QSM and generated high-quality susceptibility maps. In this paper, the network, which was…
Multiple Sclerosis (MS) is a chronic autoimmune disease that can significantly reduce the quality of life of a patient. Existing treatment options can only help slow down the progression of the disease. Therefore, early detection and…
Assessing lesions and tracking their progression over time in brain magnetic resonance (MR) images is essential for diagnosing and monitoring multiple sclerosis (MS). Machine learning models have shown promise in automating the segmentation…
Cortical lesions (CLs) have emerged as valuable biomarkers in multiple sclerosis (MS), offering high diagnostic specificity and prognostic relevance. However, their routine clinical integration remains limited due to subtle magnetic…
Segmenting stroke lesions in MRI is challenging due to diverse acquisition protocols that limit model generalisability. In this work, we introduce two physics-constrained approaches to generate synthetic quantitative MRI (qMRI) images that…
Magnetic resonance imaging is a fundamental tool to reach a diagnosis of multiple sclerosis and monitoring its progression. Although several attempts have been made to segment multiple sclerosis lesions using artificial intelligence, fully…
In this paper we present the methods of our submission to the ISIC 2018 challenge for skin lesion diagnosis (Task 3). The dataset consists of 10000 images with seven image-level classes to be distinguished by an automated algorithm. We…
The current multiple sclerosis (MS) diagnostic criteria lack specificity, and this may lead to misdiagnosis, which remains an issue in present-day clinical practice. In addition, conventional biomarkers only moderately correlate with MS…
Quantitative susceptibility mapping (QSM) estimates the underlying tissue magnetic susceptibility from MRI gradient-echo phase signal and typically requires several processing steps. These steps involve phase unwrapping, brain volume…
Multiple sclerosis (MS) is a chronic inflammatory and degenerative disease of the central nervous system, characterized by the appearance of focal lesions in the white and gray matter that topographically correlate with an individual…
Quantitative Susceptibility Mapping (QSM) can estimate the underlying tissue magnetic susceptibility and reveal pathology. Current deep-learning-based approaches to solve the QSM inverse problem are restricted on fixed image resolution.…
Universal lesion detection in computed tomography (CT) images is an important yet challenging task due to the large variations in lesion type, size, shape, and appearance. Considering that data in clinical routine (such as the DeepLesion…
Automating Multiple Sclerosis (MS) lesion segmentation would be of great benefit in initial diagnosis as well as monitoring disease progression. Deep learning based segmentation models perform well in many domains, but the state-of-the-art…