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Pathology Foundation Models (FMs) hold great promise for healthcare. Before they can be used in clinical practice, it is essential to ensure they are robust to variations between medical centers. We measure whether pathology FMs focus on…

Machine Learning · Computer Science 2025-02-04 Edwin D. de Jong , Eric Marcus , Jonas Teuwen

The Deep learning (DL) models for diagnosing breast cancer from mammographic images often operate as "black boxes", making it difficult for healthcare professionals to trust and understand their decision-making processes. The study presents…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Maryam Ahmed , Tooba Bibi , Rizwan Ahmed Khan , Sidra Nasir

Breast cancer is one of the leading causes of death across the world in women. Early diagnosis of this type of cancer is critical for treatment and patient care. Computer-aided detection (CAD) systems using convolutional neural networks…

Image and Video Processing · Electrical Eng. & Systems 2019-09-27 Sara Hosseinzadeh Kassani , Peyman Hosseinzadeh Kassani , Michal J. Wesolowski , Kevin A. Schneider , Ralph Deters

We propose small-variance asymptotic approximations for the inference of tumor heterogeneity (TH) using next-generation sequencing data. Understanding TH is an important and open research problem in biology. The lack of appropriate…

Methodology · Statistics 2015-11-17 Yanxun Xu , Peter Mueller , Yuan Yuan , Kamalakar Gulukota , Yuan Ji

Over the last decades, many prognostic models based on artificial intelligence techniques have been used to provide detailed predictions in healthcare. Unfortunately, the real-world observational data used to train and validate these models…

Machine Learning · Computer Science 2023-11-21 Alice Bernasconi , Alessio Zanga , Peter J. F. Lucas , Marco Scutari , Fabio Stella

The rapid development of deep learning, a family of machine learning techniques, has spurred much interest in its application to medical imaging problems. Here, we develop a deep learning algorithm that can accurately detect breast cancer…

Computer Vision and Pattern Recognition · Computer Science 2019-10-08 Li Shen , Laurie R. Margolies , Joseph H. Rothstein , Eugene Fluder , Russell B. McBride , Weiva Sieh

Breast cancer is the most common malignancy in women. Mammographic findings such as microcalcifications and masses, as well as morphologic features of masses in sonographic scans, are the main diagnostic targets for tumor detection.…

Computer Vision and Pattern Recognition · Computer Science 2021-07-13 Or Bar-Shira , Ahuva Grubstein , Yael Rapson , Dror Suhami , Eli Atar , Keren Peri-Hanania , Ronnie Rosen , Yonina C. Eldar

Breast cancer is the most commonly diagnosed cancer in women and a leading cause of cancer death worldwide. Screening mammography reduces mortality, yet interpretation still suffers from substantial false negatives and false positives, and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Charles Fanning , Mehmet Emin Aktas

Cancer is a highly heterogeneous condition that can occur almost anywhere in the human body. 18F-fluorodeoxyglucose is an imaging modality commonly used to detect cancer due to its high sensitivity and clear visualisation of the pattern of…

Image and Video Processing · Electrical Eng. & Systems 2023-04-17 Ashay Patel , Petru-Danial Tudiosu , Walter H. L. Pinaya , Gary Cook , Vicky Goh , Sebastien Ourselin , M. Jorge Cardoso

In the last decade, researchers working in the domain of computer vision and Artificial Intelligence (AI) have beefed up their efforts to come up with the automated framework that not only detects but also identifies stage of breast cancer.…

Image and Video Processing · Electrical Eng. & Systems 2022-01-10 Shahid Munir Shah , Rizwan Ahmed Khan , Sheeraz Arif , Unaiza Sajid

Screening mammograms are a routine imaging exam performed to detect breast cancer in its early stages to reduce morbidity and mortality attributed to this disease. In order to maximize the efficacy of breast cancer screening programs,…

Image and Video Processing · Electrical Eng. & Systems 2020-09-30 Vikash Gupta , Clayton Taylor , Sarah Bonnet , Luciano M. Prevedello , Jeffrey Hawley , Richard D White , Mona G Flores , Barbaros Selnur Erdal

To address the challenges of similarity between lesions and surrounding tissues, overlapping appearances of partially benign and malignant nodules, and difficulty in classification, a deep learning network that integrates CNN and…

Image and Video Processing · Electrical Eng. & Systems 2024-07-30 Xin Zhao , Qianqian Zhu , Jialing Wu

Deep convolutional neural networks (CNNs) have emerged as a new paradigm for Mammogram diagnosis. Contemporary CNN-based computer-aided-diagnosis (CAD) for breast cancer directly extract latent features from input mammogram image and ignore…

Image and Video Processing · Electrical Eng. & Systems 2020-08-13 Heyi Li , Dongdong Chen , William H. Nailon , Mike E. Davies , David Laurenson

Anomaly detection is the problem of recognizing abnormal inputs based on the seen examples of normal data. Despite recent advances of deep learning in recognizing image anomalies, these methods still prove incapable of handling complex…

Computer Vision and Pattern Recognition · Computer Science 2021-09-14 Nina Shvetsova , Bart Bakker , Irina Fedulova , Heinrich Schulz , Dmitry V. Dylov

Pelvic diseases in women of reproductive age represent a major global health burden, with diagnosis frequently delayed due to high anatomical variability, complicating MRI interpretation. Existing AI approaches are largely disease-specific…

Medical images differ from natural images in significantly higher resolutions and smaller regions of interest. Because of these differences, neural network architectures that work well for natural images might not be applicable to medical…

Computer Vision and Pattern Recognition · Computer Science 2020-02-19 Yiqiu Shen , Nan Wu , Jason Phang , Jungkyu Park , Kangning Liu , Sudarshini Tyagi , Laura Heacock , S. Gene Kim , Linda Moy , Kyunghyun Cho , Krzysztof J. Geras

In the last few years, deep learning classifiers have shown promising results in image-based medical diagnosis. However, interpreting the outputs of these models remains a challenge. In cancer diagnosis, interpretability can be achieved by…

Computer Vision and Pattern Recognition · Computer Science 2021-06-16 Kangning Liu , Yiqiu Shen , Nan Wu , Jakub Chłędowski , Carlos Fernandez-Granda , Krzysztof J. Geras

Breast cancer is the most common invasive cancer in women, and the second main cause of death. Breast cancer screening is an efficient method to detect indeterminate breast lesions early. The common approaches of screening for women are…

Image and Video Processing · Electrical Eng. & Systems 2021-01-26 Yuliana Jiménez Gaona , María José Rodriguez-Alvarez , Hector Espinó Morató , Darwin Castillo Malla , Vasudevan Lakshminarayanan

Data scarcity hinders deep learning for medical imaging. We propose a framework for breast cancer classification in thermograms that addresses this using a Diffusion Probabilistic Model (DPM) for data augmentation. Our DPM-based…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Sepehr Salem , M. Moein Esfahani , Jingyu Liu , Vince Calhoun

Breast cancer molecular subtypes classification plays an import role to sort patients with divergent prognosis. The biomarkers used are Estrogen Receptor (ER), Progesterone Receptor (PR), HER2, and Ki67. Based on these biomarkers expression…

Machine Learning · Computer Science 2023-10-24 Matheus del-Valle , Emerson Soares Bernardes , Denise Maria Zezell