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Current psychiatric research is in crisis. In this review I will describe the causes of this crisis and highlight recent efforts to overcome current challenges. One particularly promising approach is the emerging field of computational…

Neurons and Cognition · Quantitative Biology 2013-03-25 Thomas V. Wiecki

Brain function relies on a precisely coordinated and dynamic balance between the functional integration and segregation of distinct neural systems. Characterizing the way in which neural systems reconfigure their interactions to give rise…

Neurons and Cognition · Quantitative Biology 2021-01-28 Lingbin Bian , Tiangang Cui , B. T. Thomas Yeo , Alex Fornito , Adeel Razi , Jonathan Keith

Real-world data contains aleatoric uncertainty - irreducible noise arising from imperfect measurements or from incomplete knowledge about the data generation process. Mean-variance estimation networks can learn this type of uncertainty but…

Machine Learning · Computer Science 2026-05-29 Jiaxiang Yi , Miguel A. Bessa

Normative modeling has recently been introduced as a promising approach for modeling variation of neuroimaging measures across individuals in order to derive biomarkers of psychiatric disorders. Current implementations rely on Gaussian…

Machine Learning · Statistics 2019-04-16 Seyed Mostafa Kia , Andre F. Marquand

We show that model-based Bayesian clustering, the probabilistically most systematic approach to the partitioning of data, can be mapped into a statistical physics problem for a gas of particles, and as a result becomes amenable to a…

Disordered Systems and Neural Networks · Physics 2018-10-24 Alexander Mozeika , Anthony CC Coolen

This paper presents a new statistical method for clustering step data, a popular form of health record data easily obtained from wearable devices. Since step data are high-dimensional and zero-inflated, classical methods such as K-means and…

Methodology · Statistics 2020-10-16 Wookyeong Song , Hee-Seok Oh , Yaeji Lim , Ying Kuen Cheung

We propose a construction for joint feature learning and clustering of multichannel extracellular electrophysiological data across multiple recording periods for action potential detection and discrimination ("spike sorting"). Our…

The clustering for functional data with misaligned problems has drawn much attention in the last decade. Most methods do the clustering after those functional data being registered and there has been little research using both functional…

Methodology · Statistics 2017-11-15 Pengcheng Zeng , Jian Qing Shi , Won-Seok Kim

Causal inference is a fundamental research topic for discovering the cause-effect relationships in many disciplines. However, not all algorithms are equally well-suited for a given dataset. For instance, some approaches may only be able to…

Machine Learning · Computer Science 2024-03-11 Zhipeng Ma , Marco Kemmerling , Daniel Buschmann , Chrismarie Enslin , Daniel Lütticke , Robert H. Schmitt

In social and economic studies many of the collected variables are measured on a nominal scale, often with a large number of categories. The definition of categories is usually not unambiguous and different classification schemes using…

Methodology · Statistics 2017-03-23 Gertraud Malsiner-Walli , Daniela Pauger , Helga Wagner

The analysis of neural power spectra plays a crucial role in understanding brain function and dysfunction. While recent efforts have led to the development of methods for decomposing spectral data, challenges remain in performing…

Neurons and Cognition · Quantitative Biology 2024-10-29 Johan Medrano , Nicholas A. Alexander , Robert A. Seymour , Peter Zeidman

Functional differentiation in the brain emerges as distinct regions specialize and is key to understanding brain function as a complex system. Previous research has modeled this process using artificial neural networks with specific…

Neurons and Cognition · Quantitative Biology 2025-11-17 Yuki Tomoda , Ichiro Tsuda , Yutaka Yamaguti

In this work, we propose an original method for aggregating multiple clustering coming from different sources of information. Each partition is encoded by a co-membership matrix between observations. Our approach uses a mixture of…

Machine Learning · Computer Science 2024-01-10 Kylliann De Santiago , Marie Szafranski , Christophe Ambroise

Integrating various data modalities brings valuable insights into underlying phenomena. Multimodal factor analysis (FA) uncovers shared axes of variation underlying different simple data modalities, where each sample is represented by a…

Machine Learning · Computer Science 2025-04-29 Małgorzata Łazęcka , Ewa Szczurek

In this technical note, we address an unresolved challenge in neuroimaging statistics: how to determine which of several datasets is the best for inferring neuronal responses. Comparisons of this kind are important for experimenters when…

Understanding how the brain represents visual information is a fundamental challenge in neuroscience and artificial intelligence. While AI-driven decoding of neural data has provided insights into the human visual system, integrating…

Neural and Evolutionary Computing · Computer Science 2025-10-07 Dongyang Li , Haoyang Qin , Mingyang Wu , Chen Wei , Quanying Liu

We propose a Machine Learning approach for optimal macroeconomic density forecasting in a high-dimensional setting where the underlying model exhibits a known group structure. Our approach is general enough to encompass specific forecasting…

Econometrics · Economics 2024-11-18 Matteo Mogliani , Anna Simoni

All neuroimaging modalities have their own strengths and limitations. A current trend is toward interdisciplinary approaches that use multiple imaging methods to overcome limitations of each method in isolation. At the same time…

Methodology · Statistics 2023-03-30 Pratim Guha Niyogi , Martin A. Lindquist , Tapabrata Maiti

A standard approach for assessing the performance of partition models is to create synthetic data sets with a prespecified clustering structure, and assess how well the model reveals this structure. A common format is that subjects are…

Methodology · Statistics 2025-07-08 Michail Papathomas

Learning requires the traversal of inherently distinct cognitive states to produce behavioral adaptation. Yet, tools to explicitly measure these states with non-invasive imaging -- and to assess their dynamics during learning -- remain…