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In this study, we aim to initiate the development of Radiology Foundation Model, termed as RadFM. We consider the construction of foundational models from three perspectives, namely, dataset construction, model design, and thorough…

Computer Vision and Pattern Recognition · Computer Science 2023-11-17 Chaoyi Wu , Xiaoman Zhang , Ya Zhang , Yanfeng Wang , Weidi Xie

Deep learning in medical imaging often requires large-scale, high-quality data or initiation with suitably pre-trained weights. However, medical datasets are limited by data availability, domain-specific knowledge, and privacy concerns, and…

Image and Video Processing · Electrical Eng. & Systems 2023-12-12 Zelong Liu , Alexander Zhou , Arnold Yang , Alara Yilmaz , Maxwell Yoo , Mikey Sullivan , Catherine Zhang , James Grant , Daiqing Li , Zahi A. Fayad , Sean Huver , Timothy Deyer , Xueyan Mei

Medical image understanding requires meticulous examination of fine visual details, with particular regions requiring additional attention. While radiologists build such expertise over years of experience, it is challenging for AI models to…

Computer Vision and Pattern Recognition · Computer Science 2024-12-09 Ying Jin , Zhuoran Zhou , Haoquan Fang , Jenq-Neng Hwang

Conversational AI tools that can generate and discuss clinically correct radiology reports for a given medical image have the potential to transform radiology. Such a human-in-the-loop radiology assistant could facilitate a collaborative…

Computer Vision and Pattern Recognition · Computer Science 2025-05-08 Chantal Pellegrini , Ege Özsoy , Benjamin Busam , Nassir Navab , Matthias Keicher

In this paper, we consider the problem of disease diagnosis. Unlike the conventional learning paradigm that treats labels independently, we propose a knowledge-enhanced framework, that enables training visual representation with the…

Computer Vision and Pattern Recognition · Computer Science 2023-02-28 Chaoyi Wu , Xiaoman Zhang , Yanfeng Wang , Ya Zhang , Weidi Xie

Understanding how two radiology image sets differ is critical for generating clinical insights and for interpreting medical AI systems. We introduce RadDiff, a multimodal agentic system that performs radiologist-style comparative reasoning…

Computer Vision and Pattern Recognition · Computer Science 2026-01-08 Xiaoxian Shen , Yuhui Zhang , Sahithi Ankireddy , Xiaohan Wang , Maya Varma , Henry Guo , Curtis Langlotz , Serena Yeung-Levy

Clinical diagnosis is a highly specialized discipline requiring both domain expertise and strict adherence to rigorous guidelines. While current AI-driven medical research predominantly focuses on knowledge graphs or natural text…

Machine Learning · Computer Science 2025-12-12 Haolin Li , Tianjie Dai , Zhe Chen , Siyuan Du , Jiangchao Yao , Ya Zhang , Yanfeng Wang

Developing generalist foundation model has recently attracted tremendous attention among researchers in the field of AI for Medicine (AI4Medicine). A pivotal insight in developing these models is their reliance on dataset scaling, which…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Xiaoman Zhang , Chaoyi Wu , Ziheng Zhao , Jiayu Lei , Ya Zhang , Yanfeng Wang , Weidi Xie

Modern medical records include a vast amount of multimodal free text clinical data and imaging data from radiology, cardiology, and digital pathology. Fully mining such big data requires multitasking; otherwise, occult but important aspects…

Image and Video Processing · Electrical Eng. & Systems 2024-04-25 Chuang Niu , Qing Lyu , Christopher D. Carothers , Parisa Kaviani , Josh Tan , Pingkun Yan , Mannudeep K. Kalra , Christopher T. Whitlow , Ge Wang

Medical patient data is always multimodal. Images, text, age, gender, histopathological data are only few examples for different modalities in this context. Processing and integrating this multimodal data with deep learning based methods is…

Artificial Intelligence · Computer Science 2025-09-11 Christian Gapp , Elias Tappeiner , Martin Welk , Rainer Schubert

In recent years, accurately and quickly deploying medical large language models (LLMs) has become a trend. Among these, retrieval-augmented generation (RAG) has garnered attention due to rapid deployment and privacy protection. However, the…

Computation and Language · Computer Science 2025-08-06 Penglei Sun , Yixiang Chen , Xiang Li , Xiaowen Chu

The integration of Computer-Aided Diagnosis (CAD) with Large Language Models (LLMs) presents a promising frontier in clinical applications, notably in automating diagnostic processes akin to those performed by radiologists and providing…

Computer Vision and Pattern Recognition · Computer Science 2024-05-22 Zihao Zhao , Sheng Wang , Jinchen Gu , Yitao Zhu , Lanzhuju Mei , Zixu Zhuang , Zhiming Cui , Qian Wang , Dinggang Shen

Large language models (LLMs) often generate outdated or inaccurate information based on static training datasets. Retrieval-augmented generation (RAG) mitigates this by integrating outside data sources. While previous RAG systems used…

Recently computer-aided diagnosis has demonstrated promising performance, effectively alleviating the workload of clinicians. However, the inherent sample imbalance among different diseases leads algorithms biased to the majority…

Computer Vision and Pattern Recognition · Computer Science 2025-02-10 Li Pan , Yupei Zhang , Qiushi Yang , Tan Li , Zhen Chen

Artificial intelligence applied to retinal images offers significant potential for recognizing signs and symptoms of retinal conditions and expediting the diagnosis of eye diseases and systemic disorders. However, developing generalized…

Image and Video Processing · Electrical Eng. & Systems 2024-08-19 Boa Jang , Youngbin Ahn , Eun Kyung Choe , Chang Ki Yoon , Hyuk Jin Choi , Young-Gon Kim

Artificial Intelligence (AI) has demonstrated significant potential in healthcare, particularly in disease diagnosis and treatment planning. Recent progress in Medical Large Vision-Language Models (Med-LVLMs) has opened up new possibilities…

Machine Learning · Computer Science 2025-03-04 Peng Xia , Kangyu Zhu , Haoran Li , Tianze Wang , Weijia Shi , Sheng Wang , Linjun Zhang , James Zou , Huaxiu Yao

In the context of the long-tail scenario, models exhibit a strong demand for high-quality data. Data-centric approaches aim to enhance both the quantity and quality of data to improve model performance. Among these approaches, information…

Computer Vision and Pattern Recognition · Computer Science 2023-11-06 Yanbiao Ma , Licheng Jiao , Fang Liu , Shuyuan Yang , Xu Liu , Puhua Chen

Recent advancements in artificial intelligence (AI) have precipitated significant breakthroughs in healthcare, particularly in refining diagnostic procedures. However, previous studies have often been constrained to limited functionalities.…

Artificial Intelligence · Computer Science 2024-07-08 Asma Alkhaldi , Raneem Alnajim , Layan Alabdullatef , Rawan Alyahya , Jun Chen , Deyao Zhu , Ahmed Alsinan , Mohamed Elhoseiny

The integration of artificial intelligence (AI) with radiology marks a transformative era in medicine. Vision foundation models have been adopted to enhance radiologic imaging analysis. However, the distinct complexities of radiologic 2D…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Zhixiu Lu , Hailong Li , Nehal A. Parikh , Jonathan R. Dillman , Lili He

Recent progress in Medical Artificial Intelligence (AI) has delivered systems that can reach clinical expert level performance. However, such systems tend to demonstrate sub-optimal "out-of-distribution" performance when evaluated in…

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