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We consider the problem of independence testing for two univariate random variables in a sequential setting. By leveraging recent developments on safe, anytime-valid inference, we propose a test with time-uniform type I error control and…

Methodology · Statistics 2024-01-29 Alexander Henzi , Michael Law

Inference for causal effects can benefit from the availability of an instrumental variable (IV) which, by definition, is associated with the given exposure, but not with the outcome of interest other than through a causal exposure effect.…

Methodology · Statistics 2012-01-13 Stijn Vansteelandt , Jack Bowden , Manoochehr Babanezhad , Els Goetghebeur

We propose to validate experimentally a theory of software certification that proceeds from assessment of confidence in fault-freeness (due to standards) to conservative prediction of failure-free operation.

Software Engineering · Computer Science 2014-04-29 John Rushby , Bev Littlewood , Lorenzo Strigini

We consider the problem of conditional independence testing of $X$ and $Y$ given $Z$ where $X,Y$ and $Z$ are three real random variables and $Z$ is continuous. We focus on two main cases - when $X$ and $Y$ are both discrete, and when $X$…

Statistics Theory · Mathematics 2021-07-05 Matey Neykov , Sivaraman Balakrishnan , Larry Wasserman

This paper proposes a novel identification strategy relying on quasi-instrumental variables (quasi-IVs). A quasi-IV is a relevant but possibly invalid IV because it is not exogenous or not excluded. We show that a variety of models with…

Econometrics · Economics 2024-10-23 Christophe Bruneel-Zupanc , Jad Beyhum

Masten and Poirier (2021) introduced the falsification adaptive set (FAS) in linear models with a single endogenous variable estimated with multiple correlated instrumental variables (IVs). The FAS reflects the model uncertainty that arises…

Econometrics · Economics 2024-04-23 Nicolas Apfel , Frank Windmeijer

We demonstrate how to test for conditional independence of two variables with categorical data using Poisson log-linear models. The size of the conditioning set of variables can vary from 0 (simple independence) up to many variables. We…

Methodology · Statistics 2017-06-08 Michail Tsagris

Unobserved confounding is the main obstacle to causal effect estimation from observational data. Instrumental variables (IVs) are widely used for causal effect estimation when there exist latent confounders. With the standard IV method,…

Artificial Intelligence · Computer Science 2023-12-12 Debo Cheng , Jiuyong Li , Lin Liu , Jiji Zhang , Thuc duy Le , Jixue Liu

Adaptive experimental design methods are increasingly being used in industry as a tool to boost testing throughput or reduce experimentation cost relative to traditional A/B/N testing methods. This paper shares lessons learned regarding the…

Machine Learning · Computer Science 2022-10-27 Tanner Fiez , Sergio Gamez , Arick Chen , Houssam Nassif , Lalit Jain

We introduce a test for the conditional independence of random variables $X$ and $Y$ given a random variable $Z$, specifically by sampling from the joint distribution $(X,Y,Z)$, binning the support of the distribution of $Z$, and conducting…

Statistics Theory · Mathematics 2024-02-05 Andrew Warren

It is a common saying that testing for conditional independence, i.e., testing whether whether two random vectors $X$ and $Y$ are independent, given $Z$, is a hard statistical problem if $Z$ is a continuous random variable (or vector). In…

Statistics Theory · Mathematics 2022-03-25 Rajen D. Shah , Jonas Peters

This paper provides partial identification of various binary choice models with misreported dependent variables. We propose two distinct approaches by exploiting different instrumental variables respectively. In the first approach, the…

Econometrics · Economics 2024-01-31 Orville Mondal , Rui Wang

Test or prove? These two approaches to software verification have long been presented as opposites. One is dynamic, the other static: a test executes the program, a proof only analyzes the program text. A different perspective is emerging,…

Software Engineering · Computer Science 2026-02-10 Li Huang , Bertrand Meyer , Manuel Oriol

We propose a test of the conditional independence of random variables $X$ and~$Y$ given~$Z$ under the additional assumption that $X$ is stochastically nondecreasing in~$Z$. The well-documented hardness of testing conditional independence…

Methodology · Statistics 2026-04-24 Rohan Hore , Jake A. Soloff , Rina Foygel Barber , Richard J. Samworth

Real-time hybrid testing is a method in which a substructure of the system is realised experimentally and the rest numerically. The two parts interact in real time to emulate the dynamics of the full system. Such experiments however are…

Dynamical Systems · Mathematics 2024-06-04 Sandor Beregi , David A. W. Barton , Djamel Rezgui , Simon A. Neild

To estimate causal effects, analysts performing observational studies in health settings utilize several strategies to mitigate bias due to confounding by indication. There are two broad classes of approaches for these purposes: use of…

Methodology · Statistics 2023-05-01 Roy S. Zawadzki , Joshua D. Grill , Daniel L. Gillen

Conditional independence (CI) tests underlie many approaches to model testing and structure learning in causal inference. Most existing CI tests for categorical and ordinal data stratify the sample by the conditioning variables, perform…

Machine Learning · Statistics 2023-07-06 Ankur Ankan , Johannes Textor

Test-negative designs are widely used for post-market evaluation of vaccine effectiveness, particularly in cases when randomized trials are not feasible. Differing from classical test-negative designs where only healthcare-seekers with…

Testing conditional independence has many applications, such as in Bayesian network learning and causal discovery. Different test methods have been proposed. However, existing methods generally can not work when only discretized…

Machine Learning · Statistics 2025-03-19 Boyang Sun , Yu Yao , Guang-Yuan Hao , Yumou Qiu , Kun Zhang

Instrumental variable analysis is a widely used method to estimate causal effects in the presence of unmeasured confounding. When the instruments, exposure and outcome are not measured in the same sample, Angrist and Krueger (1992)…

Statistics Theory · Mathematics 2018-09-07 Qingyuan Zhao , Jingshu Wang , Jack Bowden , Dylan S. Small