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The rapid growth of electronic health record (EHR) datasets opens up promising opportunities to understand human diseases in a systematic way. However, effective extraction of clinical knowledge from the EHR data has been hindered by its…

Machine Learning · Computer Science 2022-06-06 Yuesong Zou , Ahmad Pesaranghader , Aman Verma , David Buckeridge , Yue Li

Knowledge Graphs (KGs) are a powerful representation of linked data, offering flexibility, semantic richness, and support for knowledge enrichment and reasoning. They help data owners organize and exploit heterogeneous data to provide…

Cryptography and Security · Computer Science 2026-05-20 Yasmine Hayder

Electronic Medical Records (EHR) are extremely sparse. Only a small proportion of events (symptoms, diagnoses, and treatments) are observed in the lifetime of an individual. The high degree of missingness of EHR can be attributed to a large…

Artificial Intelligence · Computer Science 2021-11-18 Ramon Vinas , Xu Zheng , Jer Hayes

Multimodal electronic health record (EHR) data is useful for disease risk prediction based on medical domain knowledge. However, general medical knowledge must be adapted to specific healthcare settings and patient populations to achieve…

Artificial Intelligence · Computer Science 2025-09-29 Mbithe Nzomo , Deshendran Moodley

Medical knowledge graphs (KGs) constructed from Electronic Medical Records (EMR) contain abundant information about patients and medical entities. The utilization of KG embedding models on these data has proven to be efficient for different…

Information Retrieval · Computer Science 2021-04-06 Aynur Guluzade , Endri Kacupaj , Maria Maleshkova

Knowledge Graphs (KGs) have gained considerable attention recently from both academia and industry. In fact, incorporating graph technology and the copious of various graph datasets have led the research community to build sophisticated…

Artificial Intelligence · Computer Science 2020-06-03 Bilal Abu-Salih , Marwan Al-Tawil , Ibrahim Aljarah , Hossam Faris , Pornpit Wongthongtham

Knowledge Graph (KG) is a flexible structure that is able to describe the complex relationship between data entities. Currently, most KG embedding models are trained based on negative sampling, i.e., the model aims to maximize some…

Artificial Intelligence · Computer Science 2021-06-17 Zelong Li , Jianchao Ji , Zuohui Fu , Yingqiang Ge , Shuyuan Xu , Chong Chen , Yongfeng Zhang

Knowledge graphs (KGs) are important products of the semantic web, which are widely used in various application domains. Healthcare is one of such domains where KGs are intensively used, due to the high requirement for knowledge accuracy…

Artificial Intelligence · Computer Science 2025-07-31 Yuzhang Xie , Xu Han , Ran Xu , Xiao Hu , Jiaying Lu , Carl Yang

The problem of knowledge graph (KG) reasoning has been widely explored by traditional rule-based systems and more recently by knowledge graph embedding methods. While logical rules can capture deterministic behavior in a KG they are brittle…

Artificial Intelligence · Computer Science 2020-09-24 Susheel Suresh , Jennifer Neville

Knowledge graphs (KGs) play a crucial role in many applications, such as question answering, but incompleteness is an urgent issue for their broad application. Much research in knowledge graph completion (KGC) has been performed to resolve…

Artificial Intelligence · Computer Science 2023-01-10 Yinyu Lan , Shizhu He , Kang Liu , Jun Zhao

Knowledge graphs (KGs) have been increasingly employed for link prediction and recommendation using real-world datasets. However, the majority of current methods rely on static data, neglecting the dynamic nature and the hidden…

Artificial Intelligence · Computer Science 2024-02-20 Ruiyi Yang , Flora D. Salim , Hao Xue

Knowledge graph (KG) embedding has been used to benefit the diagnosis of animal diseases by analyzing electronic medical records (EMRs), such as notes and veterinary records. However, learning representations to capture entities and…

Artificial Intelligence · Computer Science 2023-09-08 Van Thuy Hoang , Sang Thanh Nguyen , Sangmyeong Lee , Jooho Lee , Luong Vuong Nguyen , O-Joun Lee

Knowledge graphs (KGs), as structured representations of real world facts, are intelligent databases incorporating human knowledge that can help machine imitate the way of human problem solving. However, KGs are usually huge and there are…

Machine Learning · Computer Science 2023-06-27 Haotian Li , Hongri Liu , Yao Wang , Guodong Xin , Yuliang Wei

Adoption of recently developed methods from machine learning has given rise to creation of drug-discovery knowledge graphs (KG) that utilize the interconnected nature of the domain. Graph-based modelling of the data, combined with KG…

Machine Learning · Computer Science 2022-07-27 Stephen Bonner , Ufuk Kirik , Ola Engkvist , Jian Tang , Ian P Barrett

Due to the increasing adoption of electronic health records (EHR), large scale EHRs have become another rich data source for translational clinical research. Despite its potential, deriving generalizable knowledge from EHR data remains…

Machine Learning · Statistics 2023-06-01 Junwei Lu , Jin Yin , Tianxi Cai

Estimation of the accuracy of a large-scale knowledge graph (KG) often requires humans to annotate samples from the graph. How to obtain statistically meaningful estimates for accuracy evaluation while keeping human annotation costs low is…

Databases · Computer Science 2019-07-24 Junyang Gao , Xian Li , Yifan Ethan Xu , Bunyamin Sisman , Xin Luna Dong , Jun Yang

Knowledge Graph (KG) completion is an important task that greatly benefits knowledge discovery in many fields (e.g. biomedical research). In recent years, learning KG embeddings to perform this task has received considerable attention.…

Machine Learning · Computer Science 2022-08-01 Adil Bahaj , Safae Lhazmir , Mounir Ghogho

Knowledge graphs (KGs) have proven to be effective for high-quality recommendation, where the connectivities between users and items provide rich and complementary information to user-item interactions. Most existing methods, however, are…

Information Retrieval · Computer Science 2021-09-16 Xiao Sha , Zhu Sun , Jie Zhang

Knowledge Graphs (KG) and associated Knowledge Graph Embedding (KGE) models have recently begun to be explored in the context of drug discovery and have the potential to assist in key challenges such as target identification. In the drug…

Biomolecules · Quantitative Biology 2022-06-01 Stephen Bonner , Ian P Barrett , Cheng Ye , Rowan Swiers , Ola Engkvist , Charles Tapley Hoyt , William L Hamilton

Extensive adoption of electronic health records (EHRs) offers opportunities for their use in various downstream clinical analyses. To accomplish this purpose, enriching an EHR cohort with external knowledge (e.g., standardized medical…

Machine Learning · Computer Science 2024-06-13 Ahmad Wisnu Mulyadi , Heung-Il Suk
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