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Capturing complex dependence structures between outcome variables (e.g., study endpoints) is of high relevance in contemporary biomedical data problems and medical research. Distributional copula regression provides a flexible tool to model…

Methodology · Statistics 2022-02-28 Nicolai Hans , Nadja Klein , Florian Faschingbauer , Michael Schneider , Andreas Mayr

It is often of interest to study the association between covariates and the cumulative incidence of a right-censored time-to-event outcome. When time-varying covariates are measured on a fixed discrete time scale, it is desirable to account…

Methodology · Statistics 2026-04-28 Hongxiang Qiu , Marco Carone , Alex Luedtke , Peter B. Gilbert

We are studying the problems of modeling and inference for multivariate count time series data with Poisson marginals. The focus is on linear and log-linear models. For studying the properties of such processes we develop a novel conceptual…

Methodology · Statistics 2017-04-10 Paul Doukhan , Konstantinos Fokianos , Bård Støve , Dag Tjøstheim

The goal of cluster analysis in survival data is to identify clusters that are decidedly associated with the survival outcome. Previous research has explored this problem primarily in the medical domain with relatively small datasets, but…

Social and Information Networks · Computer Science 2017-03-10 S Chandra Mouli , Abhishek Naik , Bruno Ribeiro , Jennifer Neville

This paper proposes a robust Bayesian accelerated failure time model for censored survival data. We develop a new family of life-time distributions using a scale mixture of the generalized gamma distributions, where we propose a novel super…

Methodology · Statistics 2025-04-16 Yasuyuki Hamura , Takahiro Onizuka , Shintaro Hashimoto , Shonosuke Sugasawa

The instability in the selection of models is a major concern with data sets containing a large number of covariates. This paper deals with variable selection methodology in the case of high-dimensional problems where the response variable…

Applications · Statistics 2012-03-23 Marie Walschaerts , Eve Leconte , Philippe Besse

This paper extends doubly robust censoring unbiased transformations to a broad class of censored data structures under the assumption of coarsening at random and positivity. This includes the classic survival and competing risks setting,…

Methodology · Statistics 2024-11-08 Oliver Lunding Sandqvist

Previous deep learning approaches for survival analysis have primarily relied on ranking losses to improve discrimination performance, which often comes at the expense of calibration performance. To address such an issue, we propose a novel…

Machine Learning · Computer Science 2024-11-22 Dongjoon Lee , Hyeryn Park , Changhee Lee

Feature screening is an important tool in analyzing ultrahigh-dimensional data, particularly in the field of Omics and oncology studies. However, most attention has been focused on identifying features that have a linear or monotonic impact…

Methodology · Statistics 2023-05-10 Yaxian Chen , KF Lam , Zhonghua Liu

This paper is concerned with modeling the dependence structure of two (or more) time-series in the presence of a (possible multivariate) covariate which may include past values of the time series. We assume that the covariate influences…

Statistics Theory · Mathematics 2018-12-11 Natalie Neumeyer , Marek Omelka , Sarka Hudecova

Let P represent the source population with complete data, containing covariate $\mathbf{Z}$ and response $T$, and Q the target population, where only the covariate $\mathbf{Z}$ is available. We consider a setting with both label shift and…

Methodology · Statistics 2025-06-27 Yuxiang Zong , Yanyuan Ma , Ingrid Van Keilegom

While there are many well-developed data science methods for classification and regression, there are relatively few methods for working with right-censored data. Here, we present "survival stacking": a method for casting survival analysis…

Methodology · Statistics 2021-07-29 Erin Craig , Chenyang Zhong , Robert Tibshirani

A core challenge in survival analysis is to model the distribution of censored time-to-event data, where the event of interest may be a death, failure, or occurrence of a specific event. Previous studies have showed that ranking and maximum…

Machine Learning · Computer Science 2025-01-27 Liwen Zhang , Lianzhen Zhong , Fan Yang , Di Dong , Hui Hui , Jie Tian

We study the task of unsupervised domain adaptation, where no labeled data from the target domain is provided during training time. To deal with the potential discrepancy between the source and target distributions, both in features and…

Machine Learning · Computer Science 2017-10-03 Cuong D. Tran , Ognjen Rudovic , Vladimir Pavlovic

In epidemiological research, modeling the cumulative effects of time-dependent exposures on survival outcomes presents a challenge due to their intricate temporal dynamics. Conventional spline-based statistical methods, though effective,…

Machine Learning · Computer Science 2026-01-01 Kang-Chung Yang , Shinsheng Yuan

Deep neural networks for survival prediction outper-form classical approaches in discrimination, which is the ordering of patients according to their time-of-event. Conversely, classical approaches like the Cox Proportional Hazards model…

Machine Learning · Computer Science 2022-09-01 Patrick Fuhlert , Anne Ernst , Esther Dietrich , Fabian Westhaeusser , Karin Kloiber , Stefan Bonn

Modeling symptom progression to identify informative subjects for a new Huntington's disease clinical trial is problematic since time to diagnosis, a key covariate, can be heavily censored. Imputation is an appealing strategy where censored…

Methodology · Statistics 2025-02-11 Sarah C. Lotspeich , Tanya P. Garcia

Kaplan-Meier survival analysis represents the most objective measure of treatment efficacy in oncology, though subjected to potential bias, which is worrisome in an era of precision medicine. Independent of the bias inherent to the design…

Methodology · Statistics 2020-12-17 Enrique Barrajón , Laura Barrajón

Copulas are a fundamental tool for modelling multivariate dependencies in data, forming the method of choice in diverse fields and applications. However, the adoption of existing models for multimodal and high-dimensional dependencies is…

Machine Learning · Statistics 2026-05-20 David Huk , Theodoros Damoulas

The influx of deep learning (DL) techniques into the field of survival analysis in recent years has led to substantial methodological progress; for instance, learning from unstructured or high-dimensional data such as images, text or omics…

Machine Learning · Statistics 2024-02-23 Simon Wiegrebe , Philipp Kopper , Raphael Sonabend , Bernd Bischl , Andreas Bender
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