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Molecular representation learning is crucial for the problem of molecular property prediction, where graph neural networks (GNNs) serve as an effective solution due to their structure modeling capabilities. Since labeled data is often…

Machine Learning · Computer Science 2023-09-26 Cameron Diao , Kaixiong Zhou , Zirui Liu , Xiao Huang , Xia Hu

Many-Objective Feature Selection (MOFS) approaches use four or more objectives to determine the relevance of a subset of features in a supervised learning task. As a consequence, MOFS typically returns a large set of non-dominated…

Machine Learning · Computer Science 2023-12-01 Uchechukwu F. Njoku , Alberto Abelló , Besim Bilalli , Gianluca Bontempi

Artificial neural networks show promising performance in detecting correlations within data that are associated with specific outcomes. However, the black-box nature of such models can hinder the knowledge advancement in research fields by…

Machine Learning · Computer Science 2023-10-09 Jonas C. Ditz , Bernhard Reuter , Nico Pfeifer

Link prediction plays an important role in network analysis and applications. Recently, approaches for link prediction have evolved from traditional similarity-based algorithms into embedding-based algorithms. However, most existing…

Social and Information Networks · Computer Science 2020-08-11 Lei Wang , Jing Ren , Bo Xu , Jianxin Li , Wei Luo , Feng Xia

During the last decade, automatic data analysis methods concerning different aspects of crystal analysis have been developed, e.g., unsupervised primitive unit cell extraction and automated crystal distortion and defects detection. However,…

Image and Video Processing · Electrical Eng. & Systems 2023-03-24 Amel Shamseldeen Ali Alhassan , Siyuan Zhang , Benjamin Berkels

Many time series, particularly health data streams, can be best understood as a sequence of phenomenon or events, which we call \textit{motifs}. A time series motif is a short trace segment which may implicitly capture an underlying…

Machine Learning · Computer Science 2025-05-26 Josephine Lamp , Mark Derdzinski , Christopher Hannemann , Sam Hatfield , Joost van der Linden

Molecular generation plays an important role in drug discovery and materials science, especially in data-scarce scenarios where traditional generative models often struggle to achieve satisfactory conditional generalization. To address this…

Machine Learning · Computer Science 2025-05-13 Zimo Yan , Jie Zhang , Zheng Xie , Chang Liu , Yizhen Liu , Yiping Song

One of the most powerful techniques to study protein structures is to look for recurrent fragments (also called substructures or spatial motifs), then use them as patterns to characterize the proteins under study. An emergent trend consists…

Computational Engineering, Finance, and Science · Computer Science 2018-03-02 Wajdi Dhifli , Rabie Saidi , Engelbert Mephu Nguifo

The discovery of time series motifs has emerged as one of the most useful primitives in time series data mining. Researchers have shown its utility for exploratory data mining, summarization, visualization, segmentation, classification,…

Machine Learning · Computer Science 2018-02-16 Yan Zhu , Abdullah Mueen , Eamonn Keogh

We develop, analyze and experiment with a new tool, called MADMX, which extracts frequent motifs, possibly including don't care characters, from biological sequences. We introduce density, a simple and flexible measure for bounding the…

Data Structures and Algorithms · Computer Science 2010-02-05 Roberto Grossi , Andrea Pietracaprina , Nadia Pisanti , Geppino Pucci , Eli Upfal , Fabio Vandin

We study the problem of weakly supervised text classification, which aims to classify text documents into a set of pre-defined categories with category surface names only and without any annotated training document provided. Most existing…

Computation and Language · Computer Science 2023-10-24 Yu Zhang , Shweta Garg , Yu Meng , Xiusi Chen , Jiawei Han

Molecular Dynamics (MD) simulations are fundamental computational tools for the study of proteins and their free energy landscapes. However, sampling protein conformational changes through MD simulations is challenging due to the relatively…

Biomolecules · Quantitative Biology 2023-07-20 Diego E. Kleiman , Hassan Nadeem , Diwakar Shukla

This article introduces idMotif, a visual analytics framework designed to aid domain experts in the identification of motifs within protein sequences. Motifs, short sequences of amino acids, are critical for understanding the distinct…

Quantitative Methods · Quantitative Biology 2024-02-12 Ji Hwan Park , Vikash Prasad , Sydney Newsom , Fares Najar , Rakhi Rajan

Machine learning models on behavioral and textual data can result in highly accurate prediction models, but are often very difficult to interpret. Rule-extraction techniques have been proposed to combine the desired predictive accuracy of…

Artificial Intelligence · Computer Science 2021-07-01 Yanou Ramon , David Martens , Theodoros Evgeniou , Stiene Praet

Social segregation in cities, spanning racial, residential, and income dimensions, is becoming more diverse and severe. As urban spaces and social relations grow more complex, residents in metropolitan areas experience varying levels of…

Artificial Intelligence · Computer Science 2024-12-25 Tengfei He , Xiao Zhou

Network motif provides a way to uncover the basic building blocks of most complex networks. This task usually demands high computer processing, specially for motif with 5 or more vertices. This paper presents an extended methodology with…

Data Structures and Algorithms · Computer Science 2018-04-27 Luis A. A. Meira , Vinícius R. Máximo , Alvaro L. Fazenda , Arlindo F. da Conceição

Introduction: molecular geometry, the three-dimensional arrangement of atoms within a molecule, is fundamental to understanding chemical reactivity, physical properties, and biological activity. The prevailing models used to describe…

General Physics · Physics 2026-05-12 Sebastian Ali Sacasa-Cespedes

While traditional systems for Open Information Extraction were statistical and rule-based, recently neural models have been introduced for the task. Our work builds upon CopyAttention, a sequence generation OpenIE model (Cui et. al., 2018).…

Computation and Language · Computer Science 2020-05-19 Keshav Kolluru , Samarth Aggarwal , Vipul Rathore , Mausam , Soumen Chakrabarti

The standard methods for detecting differential gene expression are mostly designed for analyzing a single gene expression experiment. When data from multiple related gene expression studies are available, separately analyzing each study is…

Methodology · Statistics 2013-11-07 Yingying Wei , Hongkai Ji

The structural motifs of a Zr$_{50}$Cu$_{45}$Al$_{5}$ metallic glass were learned from atomistic models using a new structure analysis method called motif extraction that employs point-pattern matching and machine learning clustering…

Materials Science · Physics 2019-07-19 Jason J. Maldonis , Arash Dehghan Banadaki , Srikanth Patala , Paul M. Voyles