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Genes, proteins and other biological entities influence one another via causal molecular networks. Causal relationships in such networks are mediated by complex and diverse mechanisms, through latent variables, and are often specific to…

Machine Learning · Computer Science 2025-03-07 Izzy Newsham , Luka Kovačević , Richard Moulange , Nan Rosemary Ke , Sach Mukherjee

This study explores the capability of Large Language Models (LLMs) to evaluate causality in causal graphs generated by conventional statistical causal discovery methods-a task traditionally reliant on manual assessment by human subject…

Computation and Language · Computer Science 2025-04-16 Yuni Susanti , Nina Holsmoelle

Building causal graphs can be a laborious process. To ensure all relevant causal pathways have been captured, researchers often have to discuss with clinicians and experts while also reviewing extensive relevant medical literature. By…

Computation and Language · Computer Science 2024-02-26 Stephanie Long , Tibor Schuster , Alexandre Piché

Understanding and inferring causal relationships from texts is a core aspect of human cognition and is essential for advancing large language models (LLMs) towards artificial general intelligence. Existing work evaluating LLM causal…

Artificial Intelligence · Computer Science 2026-04-14 Ryan Saklad , Aman Chadha , Oleg Pavlov , Raha Moraffah

The causal capabilities of large language models (LLMs) are a matter of significant debate, with critical implications for the use of LLMs in societally impactful domains such as medicine, science, law, and policy. We conduct a "behavorial"…

Artificial Intelligence · Computer Science 2024-08-21 Emre Kıcıman , Robert Ness , Amit Sharma , Chenhao Tan

Large language models (LLMs) are trained on enormous amounts of data and encode knowledge in their parameters. We propose a pipeline to elicit causal relationships from LLMs. Specifically, (i) we sample many documents from LLMs on a given…

Machine Learning · Computer Science 2026-03-05 Takashi Kameyama , Masahiro Kato , Yasuko Hio , Yasushi Takano , Naoto Minakawa

Causal graph recovery is traditionally done using statistical estimation-based methods or based on individual's knowledge about variables of interests. They often suffer from data collection biases and limitations of individuals' knowledge.…

Computation and Language · Computer Science 2024-06-19 Yuzhe Zhang , Yipeng Zhang , Yidong Gan , Lina Yao , Chen Wang

Causal structure discovery from observations can be improved by integrating background knowledge provided by an expert to reduce the hypothesis space. Recently, Large Language Models (LLMs) have begun to be considered as sources of prior…

Machine Learning · Computer Science 2024-05-24 Victor-Alexandru Darvariu , Stephen Hailes , Mirco Musolesi

Causal reasoning capabilities are essential for large language models (LLMs) in a wide range of applications, such as education and healthcare. But there is still a lack of benchmarks for a better understanding of such capabilities. Current…

Computation and Language · Computer Science 2024-12-25 Ruibo Tu , Hedvig Kjellström , Gustav Eje Henter , Cheng Zhang

Causal structure discovery methods are commonly applied to structured data where the causal variables are known and where statistical testing can be used to assess the causal relationships. By contrast, recovering a causal structure from…

Computation and Language · Computer Science 2024-10-10 Gaël Gendron , Jože M. Rožanec , Michael Witbrock , Gillian Dobbie

Recent claims of strong performance by Large Language Models (LLMs) on causal discovery are undermined by a key flaw: many evaluations rely on benchmarks likely included in pretraining corpora. Thus, apparent success suggests that LLM-only…

As the significance of understanding the cause-and-effect relationships among variables increases in the development of modern systems and algorithms, learning causality from observational data has become a preferred and efficient approach…

Machine Learning · Computer Science 2024-11-28 Xiaoxuan Li , Yao Liu , Ruoyu Wang , Lina Yao

Causal inference has been a pivotal challenge across diverse domains such as medicine and economics, demanding a complicated integration of human knowledge, mathematical reasoning, and data mining capabilities. Recent advancements in…

Computation and Language · Computer Science 2025-02-11 Jing Ma

The safe deployment of large language models (LLMs) in high-stakes fields like biomedicine, requires them to be able to reason about cause and effect. We investigate this ability by testing 13 open-source LLMs on a fundamental task:…

Computation and Language · Computer Science 2026-03-13 Sydney Anuyah , Sneha Shajee-Mohan , Ankit-Singh Chauhan , Sunandan Chakraborty

Causality is essential in scientific research, enabling researchers to interpret true relationships between variables. These causal relationships are often represented by causal graphs, which are directed acyclic graphs. With the recent…

Computation and Language · Computer Science 2025-02-19 Ivaxi Sheth , Bahare Fatemi , Mario Fritz

Causal inference has shown potential in enhancing the predictive accuracy, fairness, robustness, and explainability of Natural Language Processing (NLP) models by capturing causal relationships among variables. The emergence of generative…

Computation and Language · Computer Science 2025-03-24 Xiaoyu Liu , Paiheng Xu , Junda Wu , Jiaxin Yuan , Yifan Yang , Yuhang Zhou , Fuxiao Liu , Tianrui Guan , Haoliang Wang , Tong Yu , Julian McAuley , Wei Ai , Furong Huang

Leveraging the synergy between causal knowledge graphs and a large language model (LLM), our study introduces a groundbreaking approach for computational hypothesis generation in psychology. We analyzed 43,312 psychology articles using a…

Artificial Intelligence · Computer Science 2024-08-19 Song Tong , Kai Mao , Zhen Huang , Yukun Zhao , Kaiping Peng

This study investigates the efficacy of Large Language Models (LLMs) in causal discovery. Using newly available open-source LLMs, OLMo and BLOOM, which provide access to their pre-training corpora, we investigate how LLMs address causal…

Computation and Language · Computer Science 2025-10-13 Tao Feng , Lizhen Qu , Niket Tandon , Zhuang Li , Xiaoxi Kang , Gholamreza Haffari

Recent work shows that causal facts can be effectively extracted from LLMs through prompting, facilitating the creation of causal graphs for causal inference tasks. However, it is unclear if this success is limited to explicitly-mentioned…

Computation and Language · Computer Science 2024-06-19 Nitish Joshi , Abulhair Saparov , Yixin Wang , He He

Objective: This study investigates the potential of Large Language Models (LLMs) as an alternative to human expert elicitation for extracting structured causal knowledge and facilitating causal modeling in biometric and healthcare…

Artificial Intelligence · Computer Science 2025-04-15 Olha Shaposhnyk , Daria Zahorska , Svetlana Yanushkevich
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