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Proteins are fundamental biological entities that play a key role in life activities. The amino acid sequences of proteins can be folded into stable 3D structures in the real physicochemical world, forming a special kind of…

Machine Learning · Computer Science 2023-01-04 Lirong Wu , Yufei Huang , Haitao Lin , Stan Z. Li

When nanoparticles (NPs) are introduced into a biological solution, layers of biomolecules form on their surface, creating a corona. Understanding how the structure of the protein evolves into the corona is essential for evaluating the…

This paper systematically reviews the research progress and application prospects of machine learning technologies in the field of polymer materials. Currently, machine learning methods are developing rapidly in polymer material research;…

Materials Science · Physics 2025-10-31 Hongtao Guo Shuai Li Shu Li

While visual reasoning for simple analogies has received significant attention, compositional visual relations (CVR) remain relatively unexplored due to their greater complexity. To solve CVR tasks, we propose Predictive Reasoning with…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Chengtai Li , Yuting He , Jianfeng Ren , Ruibin Bai , Yitian Zhao , Heng Yu , Xudong Jiang

Crystalline structure prediction is an essential prerequisite for designing materials with targeted properties. Yet, it is still an open challenge in materials design and drug discovery. Despite recent advances in computational materials…

Machine Learning · Computer Science 2025-09-29 Emmanuel Jehanno , Romain Menegaux , Julien Mairal , Sergei Grudinin

Modern high-dimensional methods often adopt the "bet on sparsity" principle, while in supervised multivariate learning statisticians may face "dense" problems with a large number of nonzero coefficients. This paper proposes a novel…

Machine Learning · Statistics 2022-02-10 Yiyuan She , Jiahui Shen , Chao Zhang

Atomic-level modeling performed at large scales enables the investigation of mesoscale materials properties with atom-by-atom resolution. The spatial complexity of such cross-scale simulations renders them unsuitable for simple human visual…

Materials Science · Physics 2022-04-05 Heejung Chung , Rodrigo Freitas , Gowoon Cheon , Evan J. Reed

Accurate prediction of polymer properties is essential for materials design, but remains challenging due to data scarcity, diverse polymer representations, and the lack of systematic evaluation across modelling choices. Here, we present…

Soft Condensed Matter · Physics 2026-03-17 Gaopeng Ren , Yijie Yang , Jiajun Zhou , Kim E. Jelfs

One of the key limitations of modern deep learning approaches lies in the amount of data required to train them. Humans, by contrast, can learn to recognize novel categories from just a few examples. Instrumental to this rapid learning…

Computer Vision and Pattern Recognition · Computer Science 2019-08-20 Pavel Tokmakov , Yu-Xiong Wang , Martial Hebert

Large-scale verifiable prompts underpin the success of Reinforcement Learning with Verifiable Rewards (RLVR), but they contain many uninformative examples and are costly to expand further. Recent studies focus on better exploiting limited…

Computation and Language · Computer Science 2026-04-23 Xin Xu , Clive Bai , Kai Yang , Tianhao Chen , Yangkun Chen , Weijie Liu , Hao Chen , Yang Wang , Saiyong Yang , Can Yang

We present a perspective on molecular machine learning (ML) in the field of chemical process engineering. Recently, molecular ML has demonstrated great potential in (i) providing highly accurate predictions for properties of pure components…

Chemical Physics · Physics 2025-09-01 Jan G. Rittig , Manuel Dahmen , Martin Grohe , Philippe Schwaller , Alexander Mitsos

Self-supervised representation learning has achieved remarkable success in recent years. By subverting the need for supervised labels, such approaches are able to utilize the numerous unlabeled images that exist on the Internet and in…

Computer Vision and Pattern Recognition · Computer Science 2021-09-01 Yilun Du , Chuang Gan , Phillip Isola

In this study, we present a novel approach along with the needed computational strategies for efficient and scalable feature engineering of the crystal structure in compounds of different chemical compositions. This approach utilizes a…

Materials Science · Physics 2021-05-25 Prathik R. Kaundinya , Kamal Choudhary , Surya R. Kalidindi

We introduce an electronic structure based representation for quantum machine learning (QML) of electronic properties throughout chemical compound space. The representation is constructed using computationally inexpensive ab initio…

Chemical Physics · Physics 2022-03-17 Konstantin Karandashev , O. Anatole von Lilienfeld

While deep learning has enabled great advances in many areas of music, labeled music datasets remain especially hard, expensive, and time-consuming to create. In this work, we introduce SimCLR to the music domain and contribute a large…

Sound · Computer Science 2021-09-28 Janne Spijkervet , John Ashley Burgoyne

Periodic material or crystal property prediction using machine learning has grown popular in recent years as it provides a computationally efficient replacement for classical simulation methods. A crucial first step for any of these…

Machine Learning · Computer Science 2024-05-08 Jonathan Balasingham , Viktor Zamaraev , Vitaliy Kurlin

Crystallization is a key step in macromolecular structure determination by crystallography. While a robust theoretical treatment of the process is available, due to the complexity of the system, the experimental process is still largely one…

Biomolecules · Quantitative Biology 2016-08-02 Irem Altan , Patrick Charbonneau , Edward H. Snell

Molecule representation learning (MRL) methods aim to embed molecules into a real vector space. However, existing SMILES-based (Simplified Molecular-Input Line-Entry System) or GNN-based (Graph Neural Networks) MRL methods either take…

Machine Learning · Computer Science 2021-09-23 Hongwei Wang , Weijiang Li , Xiaomeng Jin , Kyunghyun Cho , Heng Ji , Jiawei Han , Martin D. Burke

Machine learning potentials (MLPs) are becoming powerful tools for performing accurate atomistic simulations and crystal structure optimizations. An approach to developing MLPs employs a systematic set of polynomial invariants including…

Computational Physics · Physics 2020-11-18 Atsuto Seko

Probabilistic circuits (PCs) represent a probability distribution as a computational graph. Enforcing structural properties on these graphs guarantees that several inference scenarios become tractable. Among these properties, structured…

Machine Learning · Computer Science 2020-09-03 Meihua Dang , Antonio Vergari , Guy Van den Broeck