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Generative artificial intelligence has revolutionized the exploration of chemical space, yet a critical bottleneck remains that a substantial fraction of generated molecules is synthetically inaccessible. Current solutions, such as post-hoc…

Artificial Intelligence · Computer Science 2025-12-24 Junren Li , Luhua Lai

Machine learning techniques have been widely applied in Internet companies for various tasks, acting as an essential driving force, and feature engineering has been generally recognized as a crucial tache when constructing machine learning…

Machine Learning · Computer Science 2020-03-10 Qitao Shi , Ya-Lin Zhang , Longfei Li , Xinxing Yang , Meng Li , Jun Zhou

Materials synthesis is vital for innovations such as energy storage, catalysis, electronics, and biomedical devices. Yet, the process relies heavily on empirical, trial-and-error methods guided by expert intuition. Our work aims to support…

Retrosynthesis is the task of planning a series of chemical reactions to create a desired molecule from simpler, buyable molecules. While previous works have proposed algorithms to find optimal solutions for a range of metrics (e.g.…

Artificial Intelligence · Computer Science 2024-04-16 Austin Tripp , Krzysztof Maziarz , Sarah Lewis , Marwin Segler , José Miguel Hernández-Lobato

Despite their ability to understand chemical knowledge, large language models (LLMs) remain limited in their capacity to propose novel molecules with desired functions (e.g., drug-like properties). In addition, the molecules that LLMs…

This paper presents a novel meta learning framework for feature selection (FS) based on fuzzy similarity. The proposed method aims to recommend the best FS method from four candidate FS methods for any given dataset. This is achieved by…

Machine Learning · Computer Science 2020-05-22 Zixiao Shen , Xin Chen , Jonathan M. Garibaldi

Recent advancements in reasoning-reinforced Large Language Models (LLMs) have shown remarkable capabilities in complex reasoning tasks. However, the mechanism underlying their utilization of different human reasoning skills remains poorly…

Computation and Language · Computer Science 2025-08-15 Nghia Trung Ngo , Franck Dernoncourt , Thien Huu Nguyen

Importance of addressing soft errors in both safety critical applications and commercial consumer products is increasing, mainly due to ever shrinking geometries, higher-density circuits, and employment of power-saving techniques such as…

Hardware Architecture · Computer Science 2011-11-09 S. Tosun , N. Mansouri , E. Arvas , M. Kandemir , Yuan Xie

Feature fusion is a commonly used strategy in image retrieval tasks, which aggregates the matching responses of multiple visual features. Feasible sets of features can be either descriptors (SIFT, HSV) for an entire image or the same…

Information Retrieval · Computer Science 2018-11-01 Zhongdao Wang , Liang Zheng , Shengjin Wang

In real-world machine learning applications, data subsets correspond to especially critical outcomes: vulnerable cyclist detections are safety-critical in an autonomous driving task, and "question" sentences might be important to a dialogue…

Machine Learning · Computer Science 2020-03-03 Vincent S. Chen , Sen Wu , Zhenzhen Weng , Alexander Ratner , Christopher Ré

Randomised field experiments, such as A/B testing, have long been the gold standard for evaluating the value that new software brings to customers. However, running randomised field experiments is not always desired, possible or even…

Software Engineering · Computer Science 2022-07-04 Yuchu Liu , David Issa Mattos , Jan Bosch , Helena Holmström Olsson , Jonn Lantz

Recent applications of machine learning and statistical inference provide case studies demonstrating how such approaches can accelerate the discovery process in physical chemistry and related fields. Examples discussed in this review…

Chemical Physics · Physics 2017-06-20 Ryan B. Jadrich , Beth A. Lindquist , Thomas M. Truskett

Nowadays, the use of synthetic data has gained popularity as a cost-efficient strategy for enhancing data augmentation for improving machine learning models performance as well as addressing concerns related to sensitive data privacy.…

Machine Learning · Computer Science 2025-10-27 Ioannis E. Livieris , Nikos Alimpertis , George Domalis , Dimitris Tsakalidis

Chemical structure elucidation is a serious bottleneck in analytical chemistry today. We address the problem of identifying an unknown chemical threat given its mass spectrum and its chemical formula, a task which might take well trained…

Machine learning-based techniques open up many opportunities and improvements to derive deeper and more practical insights from data that can help businesses make informed decisions. However, the majority of these techniques focus on the…

Machine Learning · Computer Science 2024-05-10 Atefeh Mahdavi , Marco Carvalho

Finite-state controllers (FSCs), such as plans with loops, are powerful and compact representations of action selection widely used in robotics, video games and logistics. There has been steady progress on synthesizing FSCs in deterministic…

Artificial Intelligence · Computer Science 2019-05-20 Laszlo Treszkai , Vaishak Belle

With the widespread use of machine learning to support decision-making, it is increasingly important to verify and understand the reasons why a particular output is produced. Although post-training feature importance approaches assist this…

Machine learning is the science of discovering statistical dependencies in data, and the use of those dependencies to perform predictions. During the last decade, machine learning has made spectacular progress, surpassing human performance…

Machine Learning · Statistics 2016-07-13 David Lopez-Paz

Sequential Recommender Systems (SRSs) have emerged as a highly efficient approach to recommendation systems. By leveraging sequential data, SRSs can identify temporal patterns in user behaviour, significantly improving recommendation…

Evaluation of Large Language Models (LLMs) is challenging because instruction-following necessitates alignment with human values and the required set of skills varies depending on the instruction. However, previous studies have mainly…

Computation and Language · Computer Science 2024-04-16 Seonghyeon Ye , Doyoung Kim , Sungdong Kim , Hyeonbin Hwang , Seungone Kim , Yongrae Jo , James Thorne , Juho Kim , Minjoon Seo