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High-performance computing (HPC) has evolved over decades through multiple architectural transitions, from vector supercomputers to massively parallel CPU clusters and GPU-accelerated systems, continuously expanding the frontier of…

Quantum Physics · Physics 2026-04-23 Suman Raj , Siva Sai , Yogesh Simmhan , Kyle Chard , Rajkumar Buyya

Research collaborations are continuously emerging catalyzed by online platforms, where people can share their codes, calculations, data and results. These virtual research platforms are innovative, community oriented, flexible and secure as…

The high energy physics community is discussing where investment is needed to prepare software for the HL-LHC and its unprecedented challenges. The ROOT project is one of the central software players in high energy physics since decades.…

The connection and eventual integration of High-Performance Computing (HPC) with Quantum Computing (QC) represents a transformative advancement in computational technology, promising significant enhancements in solving complex, previously…

Federated learning (FL) can fully leverage large-scale terminal data while ensuring privacy and security, and is considered as a distributed alternative for the centralized machine learning. However, the issue of data heterogeneity poses…

Machine Learning · Computer Science 2025-03-27 Xianke Qiang , Zheng Chang , Ying-Chang Liang

As machine learning (ML) models become increasingly deployed through cloud infrastructures, the confidentiality of user data during inference poses a significant security challenge. Homomorphic Encryption (HE) has emerged as a compelling…

Cryptography and Security · Computer Science 2025-10-29 Tejaswini Bollikonda

Accessible machine learning algorithms, software, and diagnostic tools for energy-efficient devices and systems are extremely valuable across a broad range of application domains. In scientific domains, real-time near-sensor processing can…

Data analysis at the LHC has a very steep learning curve, which erects a formidable barrier between data and anyone who wishes to analyze data, either to study an idea or to simply understand how data analysis is performed. To make analysis…

Physics Education · Physics 2022-03-28 Sezen Sekmen , Gokhan Unel , Harrison B. Prosper , Aytul Adiguzel , Burak Sen

Technological advances in the past decade, hardware and software alike, have made access to high-performance computing (HPC) easier than ever. We review these advances from a statistical computing perspective. Cloud computing makes access…

Computation · Statistics 2021-07-19 Seyoon Ko , Hua Zhou , Jin J. Zhou , Joong-Ho Won

Particle physics has an ambitious and broad experimental programme for the coming decades. This programme requires large investments in detector hardware, either to build new facilities and experiments, or to upgrade existing ones.…

Computational Physics · Physics 2020-02-07 Johannes Albrecht , Antonio Augusto Alves , Guilherme Amadio , Giuseppe Andronico , Nguyen Anh-Ky , Laurent Aphecetche , John Apostolakis , Makoto Asai , Luca Atzori , Marian Babik , Giuseppe Bagliesi , Marilena Bandieramonte , Sunanda Banerjee , Martin Barisits , Lothar A. T. Bauerdick , Stefano Belforte , Douglas Benjamin , Catrin Bernius , Wahid Bhimji , Riccardo Maria Bianchi , Ian Bird , Catherine Biscarat , Jakob Blomer , Kenneth Bloom , Tommaso Boccali , Brian Bockelman , Tomasz Bold , Daniele Bonacorsi , Antonio Boveia , Concezio Bozzi , Marko Bracko , David Britton , Andy Buckley , Predrag Buncic , Paolo Calafiura , Simone Campana , Philippe Canal , Luca Canali , Gianpaolo Carlino , Nuno Castro , Marco Cattaneo , Gianluca Cerminara , Javier Cervantes Villanueva , Philip Chang , John Chapman , Gang Chen , Taylor Childers , Peter Clarke , Marco Clemencic , Eric Cogneras , Jeremy Coles , Ian Collier , David Colling , Gloria Corti , Gabriele Cosmo , Davide Costanzo , Ben Couturier , Kyle Cranmer , Jack Cranshaw , Leonardo Cristella , David Crooks , Sabine Crépé-Renaudin , Robert Currie , Sünje Dallmeier-Tiessen , Kaushik De , Michel De Cian , Albert De Roeck , Antonio Delgado Peris , Frédéric Derue , Alessandro Di Girolamo , Salvatore Di Guida , Gancho Dimitrov , Caterina Doglioni , Andrea Dotti , Dirk Duellmann , Laurent Duflot , Dave Dykstra , Katarzyna Dziedziniewicz-Wojcik , Agnieszka Dziurda , Ulrik Egede , Peter Elmer , Johannes Elmsheuser , V. Daniel Elvira , Giulio Eulisse , Steven Farrell , Torben Ferber , Andrej Filipcic , Ian Fisk , Conor Fitzpatrick , José Flix , Andrea Formica , Alessandra Forti , Giovanni Franzoni , James Frost , Stu Fuess , Frank Gaede , Gerardo Ganis , Robert Gardner , Vincent Garonne , Andreas Gellrich , Krzysztof Genser , Simon George , Frank Geurts , Andrei Gheata , Mihaela Gheata , Francesco Giacomini , Stefano Giagu , Manuel Giffels , Douglas Gingrich , Maria Girone , Vladimir V. Gligorov , Ivan Glushkov , Wesley Gohn , Jose Benito Gonzalez Lopez , Isidro González Caballero , Juan R. González Fernández , Giacomo Govi , Claudio Grandi , Hadrien Grasland , Heather Gray , Lucia Grillo , Wen Guan , Oliver Gutsche , Vardan Gyurjyan , Andrew Hanushevsky , Farah Hariri , Thomas Hartmann , John Harvey , Thomas Hauth , Benedikt Hegner , Beate Heinemann , Lukas Heinrich , Andreas Heiss , José M. Hernández , Michael Hildreth , Mark Hodgkinson , Stefan Hoeche , Burt Holzman , Peter Hristov , Xingtao Huang , Vladimir N. Ivanchenko , Todor Ivanov , Jan Iven , Brij Jashal , Bodhitha Jayatilaka , Roger Jones , Michel Jouvin , Soon Yung Jun , Michael Kagan , Charles William Kalderon , Meghan Kane , Edward Karavakis , Daniel S. Katz , Dorian Kcira , Oliver Keeble , Borut Paul Kersevan , Michael Kirby , Alexei Klimentov , Markus Klute , Ilya Komarov , Dmitri Konstantinov , Patrick Koppenburg , Jim Kowalkowski , Luke Kreczko , Thomas Kuhr , Robert Kutschke , Valentin Kuznetsov , Walter Lampl , Eric Lancon , David Lange , Mario Lassnig , Paul Laycock , Charles Leggett , James Letts , Birgit Lewendel , Teng Li , Guilherme Lima , Jacob Linacre , Tomas Linden , Miron Livny , Giuseppe Lo Presti , Sebastian Lopienski , Peter Love , Adam Lyon , Nicolò Magini , Zachary L. Marshall , Edoardo Martelli , Stewart Martin-Haugh , Pere Mato , Kajari Mazumdar , Thomas McCauley , Josh McFayden , Shawn McKee , Andrew McNab , Rashid Mehdiyev , Helge Meinhard , Dario Menasce , Patricia Mendez Lorenzo , Alaettin Serhan Mete , Michele Michelotto , Jovan Mitrevski , Lorenzo Moneta , Ben Morgan , Richard Mount , Edward Moyse , Sean Murray , Armin Nairz , Mark S. Neubauer , Andrew Norman , Sérgio Novaes , Mihaly Novak , Arantza Oyanguren , Nurcan Ozturk , Andres Pacheco Pages , Michela Paganini , Jerome Pansanel , Vincent R. Pascuzzi , Glenn Patrick , Alex Pearce , Ben Pearson , Kevin Pedro , Gabriel Perdue , Antonio Perez-Calero Yzquierdo , Luca Perrozzi , Troels Petersen , Marko Petric , Andreas Petzold , Jónatan Piedra , Leo Piilonen , Danilo Piparo , Jim Pivarski , Witold Pokorski , Francesco Polci , Karolos Potamianos , Fernanda Psihas , Albert Puig Navarro , Günter Quast , Gerhard Raven , Jürgen Reuter , Alberto Ribon , Lorenzo Rinaldi , Martin Ritter , James Robinson , Eduardo Rodrigues , Stefan Roiser , David Rousseau , Gareth Roy , Grigori Rybkine , Andre Sailer , Tai Sakuma , Renato Santana , Andrea Sartirana , Heidi Schellman , Jaroslava Schovancová , Steven Schramm , Markus Schulz , Andrea Sciabà , Sally Seidel , Sezen Sekmen , Cedric Serfon , Horst Severini , Elizabeth Sexton-Kennedy , Michael Seymour , Davide Sgalaberna , Illya Shapoval , Jamie Shiers , Jing-Ge Shiu , Hannah Short , Gian Piero Siroli , Sam Skipsey , Tim Smith , Scott Snyder , Michael D. Sokoloff , Panagiotis Spentzouris , Hartmut Stadie , Giordon Stark , Gordon Stewart , Graeme A. Stewart , Arturo Sánchez , Alberto Sánchez-Hernández , Anyes Taffard , Umberto Tamponi , Jeff Templon , Giacomo Tenaglia , Vakhtang Tsulaia , Christopher Tunnell , Eric Vaandering , Andrea Valassi , Sofia Vallecorsa , Liviu Valsan , Peter Van Gemmeren , Renaud Vernet , Brett Viren , Jean-Roch Vlimant , Christian Voss , Margaret Votava , Carl Vuosalo , Carlos Vázquez Sierra , Romain Wartel , Gordon T. Watts , Torre Wenaus , Sandro Wenzel , Mike Williams , Frank Winklmeier , Christoph Wissing , Frank Wuerthwein , Benjamin Wynne , Zhang Xiaomei , Wei Yang , Efe Yazgan

Hardware specialization is becoming a key enabler of energyefficient performance. Future systems will be increasingly heterogeneous, integrating multiple specialized and programmable accelerators, each with different memory demands.…

Hardware Architecture · Computer Science 2021-04-26 Johnathan Alsop , Weon Taek Na , Matthew D. Sinclair , Samuel Grayson , Sarita V. Adve

Chapter 17 in High-Luminosity Large Hadron Collider (HL-LHC) : Preliminary Design Report. The Large Hadron Collider (LHC) is one of the largest scientific instruments ever built. Since opening up a new energy frontier for exploration in…

Accelerator Physics · Physics 2017-05-29 C. Adorisio , I. Bejar Alonso , J. C. Gascon , T. Otto , S. Roesler

The advances in data, computing and networking over the last two decades led to a shift in many application domains that includes machine learning on big data as a part of the scientific process, requiring new capabilities for integrated…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-03-19 Ilkay Altintas , Kyle Marcus , Isaac Nealey , Scott L. Sellars , John Graham , Dima Mishin , Joel Polizzi , Daniel Crawl , Thomas DeFanti , Larry Smarr

The rapid scaling of large language models (LLMs) has unveiled critical limitations in current hardware architectures, including constraints in memory capacity, computational efficiency, and interconnection bandwidth. DeepSeek-V3, trained…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-12-24 Chenggang Zhao , Chengqi Deng , Chong Ruan , Damai Dai , Huazuo Gao , Jiashi Li , Liyue Zhang , Panpan Huang , Shangyan Zhou , Shirong Ma , Wenfeng Liang , Ying He , Yuqing Wang , Yuxuan Liu , Y. X. Wei

Data-intensive physics facilities are increasingly reliant on heterogeneous and large-scale data processing and computational systems in order to collect, distribute, process, filter, and analyze the ever increasing huge volumes of data…

High Energy Physics - Experiment · Physics 2022-03-21 Rainer Bartoldus , Catrin Bernius , David W. Miller

There are numerous approaches to building analysis applications across the high-energy physics community. Among them are Python-based, or at least Python-driven, analysis workflows. We aim to ease the adoption of a Python-based analysis…

Computational Physics · Physics 2018-04-25 David Lange

In this work, we present a new approach to high level synthesis (HLS), where high level functions are first mapped to an architectural template, before hardware synthesis is performed. As FPGA platforms are especially suitable for…

Hardware Architecture · Computer Science 2016-06-22 Shaoyi Cheng , John Wawrzynek

In our former works we have made serious efforts to improve the performance of medical image analysis methods with using ensemble-based systems. In this paper, we present a novel hardware-based solution for the efficient adoption of our…

Image and Video Processing · Electrical Eng. & Systems 2018-06-19 Laszlo Kovacs , Roland Kovacs , Andras Hajdu

quest for processing speed potential. In fact, we always get a fraction of the technically available computing power (so-called {\em theoretical peak}), and the gap is likely to go hand-to-hand with the hardware complexity of the target…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-06-23 Claude Tadonki

High Performance Computing (HPC) centers provide advanced infrastructure that enables scientific research at extreme scale. These centers operate with hardware configurations, software environments, and security requirements that differ…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-12-03 Sean R. Wilkinson , Patrick Widener , Sarp Oral , Rafael Ferreira da Silva