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Neural networks are increasingly used to estimate parameters in quantitative MRI, in particular in magnetic resonance fingerprinting. Their advantages over the gold standard non-linear least square fitting are their superior speed and their…

Characterization of quantum objects, being them states, processes, or measurements, complemented by previous knowledge about them is a valuable approach, especially as it leads to routine procedures for real-life components. To this end,…

Quantum Physics · Physics 2023-06-28 Massimiliano Guarneri , Ilaria Gianani , Marco Barbieri , Andrea Chiuri

The Bayesian Cram\'er-Rao bound (CRB) provides a lower bound on the mean square error of any Bayesian estimator under mild regularity conditions. It can be used to benchmark the performance of statistical estimators, and provides a…

Machine Learning · Statistics 2024-09-09 Evan Scope Crafts , Xianyang Zhang , Bo Zhao

Quantum neural networks (QNNs) use parameterized quantum circuits with data-dependent inputs and generate outputs through the evaluation of expectation values. Calculating these expectation values necessitates repeated circuit evaluations,…

Quantum Physics · Physics 2024-06-26 David A. Kreplin , Marco Roth

We extend the traditional framework for estimating subspace bases that maximize the preserved signal energy to additionally preserve the Cram\'er-Rao bound (CRB) of the biophysical parameters and, ultimately, improve accuracy and precision…

Medical Physics · Physics 2025-10-28 Andrew Mao , Sebastian Flassbeck , Cem Gultekin , Jakob Assländer

The Cram\'er-Rao bound (CRB), a well-known lower bound on the performance of any unbiased parameter estimator, has been used to study a wide variety of problems. However, to obtain the CRB, requires an analytical expression for the…

Machine Learning · Computer Science 2022-10-11 Hai Victor Habi , Hagit Messer , Yoram Bresler

Neural Networks (NNs) have been extensively used for a wide spectrum of real-world regression tasks, where the goal is to predict a numerical outcome such as revenue, effectiveness, or a quantitative result. In many such tasks, the point…

Machine Learning · Computer Science 2020-06-05 Xin Qiu , Elliot Meyerson , Risto Miikkulainen

Purpose: Previous quantitative MR imaging studies using self-supervised deep learning have reported biased parameter estimates at low SNR. Such systematic errors arise from the choice of Mean Squared Error (MSE) loss function for network…

Machine Learning · Computer Science 2025-09-25 Christopher S. Parker , Anna Schroder , Sean C. Epstein , James Cole , Daniel C. Alexander , Hui Zhang

A deep neural network (NN) is used to simultaneously detect laser beams in images and measure their center coordinates, radii and angular orientations. A dataset of images containing simulated laser beams and a dataset of images with…

Optics · Physics 2022-02-17 Lucas R. Hofer , Milan Krstajić , Robert P. Smith

A lower bound on the minimum mean-squared error (MSE) in a Bayesian estimation problem is proposed in this paper. This bound utilizes a well-known connection to the deterministic estimation setting. Using the prior distribution, the bias…

Information Theory · Computer Science 2009-05-27 Zvika Ben-Haim , Yonina C. Eldar

We derive a new margin-based regularization formulation, termed multi-margin regularization (MMR), for deep neural networks (DNNs). The MMR is inspired by principles that were applied in margin analysis of shallow linear classifiers, e.g.,…

Machine Learning · Computer Science 2020-09-15 Berry Weinstein , Shai Fine , Yacov Hel-Or

Bayesian neural networks (BNNs) have recently regained a significant amount of attention in the deep learning community due to the development of scalable approximate Bayesian inference techniques. There are several advantages of using a…

Machine Learning · Statistics 2023-05-02 Aliaksandr Hubin , Geir Storvik

Analytical phase demodulation algorithms in optical interferometry typically fail to reach the theoretical sensitivity limit set by the Cram\'er-Rao bound (CRB). We show that deep neural networks (DNNs) can perform efficient phase…

Image and Video Processing · Electrical Eng. & Systems 2020-08-26 Jacob Black , Shichao Chen , Joseph G. Thomas , Yizheng Zhu

We introduce a method to train Quantized Neural Networks (QNNs) --- neural networks with extremely low precision (e.g., 1-bit) weights and activations, at run-time. At train-time the quantized weights and activations are used for computing…

Neural and Evolutionary Computing · Computer Science 2016-09-23 Itay Hubara , Matthieu Courbariaux , Daniel Soudry , Ran El-Yaniv , Yoshua Bengio

Quantum error mitigation (QEM) provides a practical route for estimating reliable observables on noisy intermediate-scale quantum (NISQ) devices. Traditional QEM strategies, including zero-noise extrapolation (ZNE) and Clifford data…

Quantum Physics · Physics 2026-04-21 Huaxin Wang , Xinge Wu , Jiajun Liu , Ruiqing He , Jiandong Shang , Hengliang Guo , Qiang Chen

Measuring geometric similarity between high-dimensional network representations is a topic of longstanding interest to neuroscience and deep learning. Although many methods have been proposed, only a few works have rigorously analyzed their…

Machine Learning · Statistics 2023-12-12 Dean A. Pospisil , Brett W. Larsen , Sarah E. Harvey , Alex H. Williams

We introduce a reproducible, bias-resistant machine learning framework that integrates domain-informed feature engineering, nested cross-validation, and calibrated decision-threshold optimization for small-sample neuroimaging data.…

Machine Learning · Computer Science 2026-02-04 Jagan Mohan Reddy Dwarampudi , Jennifer L Purks , Joshua Wong , Renjie Hu , Tania Banerjee

We propose a statistical framework for the problem of parameter estimation from a noisy optomechanical system. The Cram\'er-Rao lower bound on the estimation errors in the long-time limit is derived and compared with the errors of…

Optics · Physics 2013-10-31 Shan Zheng Ang , Glen I. Harris , Warwick P. Bowen , Mankei Tsang

Bayesian Neural Networks (BNNs) provide a tool to estimate the uncertainty of a neural network by considering a distribution over weights and sampling different models for each input. In this paper, we propose a method for uncertainty…

Machine Learning · Computer Science 2024-10-28 Illia Oleksiienko , Dat Thanh Tran , Alexandros Iosifidis

Shrinkage estimation usually reduces variance at the cost of bias. But when we care only about some parameters of a model, I show that we can reduce variance without incurring bias if we have additional information about the distribution of…

Statistics Theory · Mathematics 2017-11-01 Jann Spiess
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