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Predicting and enhancing inherent properties based on molecular structures is paramount to design tasks in medicine, materials science, and environmental management. Most of the current machine learning and deep learning approaches have…

Machine Learning · Computer Science 2024-04-08 Zachary R. Fox , Ayana Ghosh

The transport and chemical reactions of solutes are modelled as a cellular automaton in which molecules of different species perform a random walk on a regular lattice and react according to a local probabilistic rule. The model describes…

comp-gas · Physics 2009-10-22 T. Karapiperis , B. Blankleider

The phenomenon where cells with elongated protrusions, such as neurons, communicate by contacting other cells and arrange themselves appropriately is termed cell sorting through haptotaxis. This phenomenon is described by partial…

Analysis of PDEs · Mathematics 2026-01-01 Hiroshi Ishii , Hideki Murakawa , Yoshitaro Tanaka

Cells encounter a diverse array of physical and chemical signals as they navigate their natural surroundings. However, their response to the simultaneous presence of multiple cues remains elusive. Particularly, the impact of topography…

Analysis of PDEs · Mathematics 2026-03-10 Valeria Cuentas , Elio Espejo

Proteins have been empirically linked to memory. If memory relates to protein structure, then each conformation would_functionally_ code only one bit, making it difficult to explain large memories. Nor is there a simple way to relate memory…

General Physics · Physics 2011-07-22 C. K. Raju

A dynamical model for quantum channel is introduced which allows one to pass continuously from the memoryless case to the case in which memory effects are present. The quantum and classical communication rates of the model are defined and…

Quantum Physics · Physics 2009-11-11 Vittorio Giovannetti

This article shows how to specify and construct a discrete, stochastic, continuous-time model specifically for ecological systems. The model is more broad than typical chemical kinetics models in two ways. First, using time-dependent hazard…

Populations and Evolution · Quantitative Biology 2015-06-30 Andrew J. Dolgert

Mobile microscopic bodies, such as motile cells, can be modelled phenomenologically as ``active particles'' which can move against external forces by depleting an internal energy depot. The microscopic mechanisms underlying such ``active''…

Statistical Mechanics · Physics 2024-02-01 Diego Marcel Fieguth

A continuum model of epithelial tissue mechanics was formulated using cellular-level mechanical ingredients and cell morphogenetic processes, including cellular shape changes and cellular rearrangements. This model can include finite…

Tissues and Organs · Quantitative Biology 2017-09-06 Shuji Ishihara , Philippe Marcq , Kaoru Sugimura

For navigation, microscopic agents such as biological cells rely on noisy sensory input. In cells performing chemotaxis, such noise arises from the stochastic binding of signaling molecules at low concentrations. Using chemotaxis of sperm…

Biological Physics · Physics 2018-07-04 Justus A. Kromer , Steffen Märcker , Steffen Lange , Christel Baier , Benjamin M. Friedrich

Memory effects in time-series of experimental observables are ubiquitous, have important cosequences for the interpretation of kinetic data, and may even affect the function of biomolecular nanomachines such as enzymes. Here we propose a…

Statistical Mechanics · Physics 2021-06-02 Alessio Lapolla , Aljaž Godec

Complex spatial patterns in biological systems often arise through self-organization without a central coordination, guided by local interactions and chemical signaling. In this study, we explore how motility-dependent chemical deposition…

Biological Physics · Physics 2025-04-24 Subhashree Subhrasmita Khuntia , Debasish Chaudhuri , Abhishek Chaudhuri

Dynamic properties of molecular motors that fuel their motion by actively interacting with underlying molecular tracks are studied theoretically via discrete-state stochastic ``burnt-bridge'' models. The transport of the particles is viewed…

Soft Condensed Matter · Physics 2009-11-13 Maxim N. Artyomov , Alexander Yu. Morozov , Ekaterina Pronina , Anatoly B. Kolomeisky

In medical imaging, technical progress or changes in diagnostic procedures lead to a continuous change in image appearance. Scanner manufacturer, reconstruction kernel, dose, other protocol specific settings or administering of contrast…

Machine Learning · Computer Science 2020-07-08 Johannes Hofmanninger , Matthias Perkonigg , James A. Brink , Oleg Pianykh , Christian Herold , Georg Langs

Living cells use readout molecules to record the state of receptor proteins, similar to measurements or copies in typical computational devices. But is this analogy rigorous? Can cells be optimally efficient, and if not, why? We show that,…

Molecular Networks · Quantitative Biology 2017-04-12 Thomas E. Ouldridge , Christopher C. Govern , Pieter Rein ten Wolde

We consider random walks on quasi one dimensional lattices, as introduced in \cite{FS}. This mathematical setting covers a large class of discrete kinetic models for non-cooperative molecular motors on periodic tracks. We derive general…

Probability · Mathematics 2015-06-19 Alessandra Faggionato , Vittoria Silvestri

We study some attraction repulsion chemotaxis models, characterized by nonlinearities laws for the diffusion of the cell density, and for the chemosensitivities and the production rates of the chemoattractant and the chemorepellent.…

Analysis of PDEs · Mathematics 2024-05-07 Tongxing Li , Daniel Acosta Soba , Alessandro Columbu , Giuseppe Viglialoro

We investigate single-cell directional sensing from diffusing chemoattractant signals released by a localized source. We focus on the low-concentration regime in which receptor activity is discrete and cellular decisions are made on…

Cell Behavior · Quantitative Biology 2026-03-12 Vincent Fiorino , Sean D. Lawley , Alan E. Lindsay

Chemotaxis is the physical phenomenon that bacteria adjust their motions according to chemical stimulus. A classical model for this phenomenon is a kinetic equation that describes the velocity jump process whose tumbling/transition kernel…

Analysis of PDEs · Mathematics 2024-01-11 Kathrin Hellmuth , Christian Klingenberg , Qin Li , Min Tang

We study some zero-flux attraction-repulsion chemotaxis models, with nonlinear production rates for the chemorepellent and the chemoattractant. This paper partially improves some known results in the literature and moreover solves an open…

Analysis of PDEs · Mathematics 2022-08-12 Alessandro Columbu , Silvia Frassu , Giuseppe Viglialoro