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Electronic Health Records (EHR) are data generated during routine clinical care. EHR offer researchers unprecedented phenotypic breadth and depth and have the potential to accelerate the pace of precision medicine at scale. A main EHR…

Quantitative Methods · Quantitative Biology 2017-04-28 Vaclav Papez , Spiros Denaxas , Harry Hemingway

Hospitals struggle to predict critical outcomes. Traditional early warning systems, like NEWS and MEWS, rely on static variables and fixed thresholds, limiting their adaptability, accuracy, and personalization. We previously developed the…

Electronic health records (EHRs) are longitudinal records of a patient's interactions with healthcare systems. A patient's EHR data is organized as a three-level hierarchy from top to bottom: patient journey - all the experiences of…

Machine Learning · Computer Science 2020-09-29 Xueping Peng , Guodong Long , Tao Shen , Sen Wang , Jing Jiang , Chengqi Zhang

Longitudinal data in electronic health records (EHRs) represent an individual`s clinical history through a sequence of codified concepts, including diagnoses, procedures, medications, and laboratory tests. Generative pre-trained…

Sharing electronic health records (EHRs) on a large scale may lead to privacy intrusions. Recent research has shown that risks may be mitigated by simulating EHRs through generative adversarial network (GAN) frameworks. Yet the methods…

Machine Learning · Computer Science 2020-03-25 Chao Yan , Ziqi Zhang , Steve Nyemba , Bradley A. Malin

Modern electronic health records (EHRs) provide data to answer clinically meaningful questions. The growing data in EHRs makes healthcare ripe for the use of machine learning. However, learning in a clinical setting presents unique…

Machine Learning · Computer Science 2019-12-09 Marzyeh Ghassemi , Tristan Naumann , Peter Schulam , Andrew L. Beam , Irene Y. Chen , Rajesh Ranganath

Electronic Health Records (EHR) have revolutionized healthcare by digitizing patient data, improving accessibility, and streamlining clinical workflows. However, extracting meaningful insights from these complex and multimodal datasets…

Artificial Intelligence · Computer Science 2025-10-27 Naama Kashani , Mira Cohen , Uri Shaham

Patient representation learning based on electronic health records (EHR) is a critical task for disease prediction. This task aims to effectively extract useful information on dynamic features. Although various existing works have achieved…

Machine Learning · Computer Science 2024-01-02 Ziyue Yu , Jiayi Wang , Wuman Luo , Rita Tse , Giovanni Pau

Electronic Health Records (EHRs) contain rich patient information and are crucial for clinical research and practice. In recent years, deep learning models have been applied to EHRs, but they often rely on massive features, which may not be…

Machine Learning · Computer Science 2024-06-11 Ran Xu , Yiwen Lu , Chang Liu , Yong Chen , Yan Sun , Xiao Hu , Joyce C Ho , Carl Yang

Foundation models trained on large-scale de-identified electronic health records (EHRs) hold promise for clinical applications. However, their capacity to memorize patient information raises important privacy concerns. In this work, we…

Machine Learning · Computer Science 2025-10-16 Sana Tonekaboni , Lena Stempfle , Adibvafa Fallahpour , Walter Gerych , Marzyeh Ghassemi

Objective: Patient notes in electronic health records (EHRs) may contain critical information for medical investigations. However, the vast majority of medical investigators can only access de-identified notes, in order to protect the…

Computation and Language · Computer Science 2016-06-14 Franck Dernoncourt , Ji Young Lee , Ozlem Uzuner , Peter Szolovits

When a deep learning model is trained sequentially on different datasets, it often forgets the knowledge learned from previous data, a problem known as catastrophic forgetting. This damages the model's performance on diverse datasets, which…

In healthcare, applying deep learning models to electronic health records (EHRs) has drawn considerable attention. EHR data consist of a sequence of medical visits, i.e. a multivariate time series of diagnosis, medications, physical…

Machine Learning · Computer Science 2018-10-19 Jing Mei , Shiwan Zhao , Feng Jin , Eryu Xia , Haifeng Liu , Xiang Li

Objective: We investigate whether deep learning techniques for natural language processing (NLP) can be used efficiently for patient phenotyping. Patient phenotyping is a classification task for determining whether a patient has a medical…

Massive electronic health records (EHRs) enable the success of learning accurate patient representations to support various predictive health applications. In contrast, doctor representation was not well studied despite that doctors play…

Machine Learning · Computer Science 2019-11-26 Siddharth Biswal , Cao Xiao , Lucas M. Glass , Elizabeth Milkovits , Jimeng Sun

Electronic Health Records (EHR) systematically organize patient health data through standardized medical codes, serving as a comprehensive and invaluable source for predictive modeling. Graph neural networks (GNNs) have demonstrated…

Machine Learning · Computer Science 2025-08-29 Haiyan Wang , Ye Yuan

Synthetic Electronic Health Records (EHR) have emerged as a pivotal tool in advancing healthcare applications and machine learning models, particularly for researchers without direct access to healthcare data. Although existing methods,…

The use of networks to integrate different genetic, proteomic, and metabolic datasets has been proposed as a viable path toward elucidating the origins of specific diseases. Here we introduce a new phenotypic database summarizing…

Biological Physics · Physics 2015-05-14 Cesar A. Hidalgo , Nicholas Blumm , Albert-Laszlo Barabasi , Nicholas Christakis

Predicting diagnoses from Electronic Health Records (EHRs) is an important medical application of multi-label learning. We propose a convolutional residual model for multi-label classification from doctor notes in EHR data. A given patient…

Machine Learning · Statistics 2018-08-10 Xinyuan Zhang , Ricardo Henao , Zhe Gan , Yitong Li , Lawrence Carin

Deep learning has demonstrated success in many applications; however, their use in healthcare has been limited due to the lack of transparency into how they generate predictions. Algorithms such as Recurrent Neural Networks (RNNs) when…

Machine Learning · Computer Science 2021-01-14 Long V. Ho , Melissa D. Aczon , David Ledbetter , Randall Wetzel