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We consider optimal sensor placement for a family of linear Bayesian inverse problems characterized by a deterministic hyper-parameter. The hyper-parameter describes distinct configurations in which measurements can be taken of the observed…

Numerical Analysis · Mathematics 2023-01-31 Nicole Aretz , Peng Chen , Denise Degen , Karen Veroy

Accurate electromagnetic modeling of the head of a subject is of main interest in the fields of source reconstruction and brain stimulation. Those processes rely heavily on the quality of the model and, even though the geometry of the…

Medical Physics · Physics 2022-02-15 Martin Grignard , Christophe Geuzaine , Christophe Phillips

We optimize the path of a mobile sensor to minimize the posterior uncertainty of a Bayesian inverse problem. Along its path, the sensor continuously takes measurements of the state, which is a physical quantity modeled as the solution of a…

Computational Engineering, Finance, and Science · Computer Science 2025-09-22 Nicole Aretz , Thomas Lynn , Karen Willcox , Sven Leyffer

In this paper, we analyze electroencephalograms (EEG) which are recordings of brain electrical activity. We develop new clustering methods for identifying synchronized brain regions, where the EEGs show similar oscillations or waveforms…

Methodology · Statistics 2020-07-29 Tianbo Chen , Ying Sun , Carolina Euan , Hernando Ombao

Electromagnetic medical imaging in the microwave regime is a hard problem notorious for 1) instability 2) under-determinism. This two-pronged problem is tackled with a two-pronged solution that uses double compression to maximally utilizing…

Medical Physics · Physics 2021-07-26 A. Al-Saffar , L. Guo , A. Abbosh

We consider the problem in Electrical Impedance Tomography (EIT) of identifying one or multiple inclusions in a background-conducting body $\Omega\subset\mathbb{R}^2$, from the knowledge of a finite number of electrostatic measurements…

Numerical Analysis · Mathematics 2025-02-07 Romina Gaburro , Patrick Healy , Shraddha Naidu , Clifford Nolan

An efficient computational approach for imaging binary-type physical properties suitable for various models in biomedical applications is developed and validated. The proposed methodology includes gradient-based multiscale optimization with…

Optimization and Control · Mathematics 2024-01-30 Maria M. F. M. Chun , Briana L. Edwards , Vladislav Bukshtynov

Brain-Machine Interfacing (BMI) has greatly benefited from adopting machine learning methods for feature learning that require extensive data for training, which are often unavailable from a single dataset. Yet, it is difficult to combine…

Signal Processing · Electrical Eng. & Systems 2024-05-27 Jinpei Han , Xiaoxi Wei , A. Aldo Faisal

We propose an optimization algorithm to compute the optimal sensor locations in experimental design in the formulation of Bayesian inverse problems, where the parameter-to-observable mapping is described through an integral equation and its…

Computation · Statistics 2019-12-30 Jing Yu , Mihai Anitescu

Bayesian Optimal Experimental Design (BOED) is a powerful tool to reduce the cost of running a sequence of experiments. When based on the Expected Information Gain (EIG), design optimization corresponds to the maximization of some…

Machine Learning · Statistics 2025-03-14 Jacopo Iollo , Christophe Heinkelé , Pierre Alliez , Florence Forbes

Stroke is a major cause of death and disability worldwide. Accurate outcome and evolution prediction has the potential to revolutionize stroke care by individualizing clinical decision-making leading to better outcomes. However, despite a…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Adam Marcus , Paul Bentley , Daniel Rueckert

Template-based signal detection most often relies on computing a correlation, or a dot product, between an incoming data stream and a signal template. Such a correlation results in an ongoing estimate of the magnitude of the signal in the…

Computational Physics · Physics 2011-07-08 M. Asim Mubeen , Kevin H. Knuth

This paper presents a mathematical framework for a flexible pressure-sensor model using electrical impedance tomography (EIT). When pressure is applied to a conductive membrane patch with clamped boundary, the pressure-induced surface…

Analysis of PDEs · Mathematics 2014-09-15 Habib Ammari , Kyungkeun Kang , Kyounghun Lee , Jin Keun Seo

Epileptic seizure detection from EEG signals remains challenging due to the high dimensionality and nonlinear, potentially stochastic, dynamics of neural activity. In this work, we investigate whether features derived from topological data…

Machine Learning · Computer Science 2026-04-15 Sunia Tanweer , Narayan Puthanmadam Subramaniyam , Firas A. Khasawneh

In this paper, we explore the multiple source localisation problem in the cerebral cortex using magnetoencephalography (MEG) data. We model neural currents as point-wise dipolar sources which dynamically evolve over time, then model dipole…

Applications · Statistics 2015-06-18 Xi Chen , Simo Särkkä , Simon Godsill

The midline related pathological image features are crucial for evaluating the severity of brain compression caused by stroke or traumatic brain injury (TBI). The automated midline delineation not only improves the assessment and clinical…

Image and Video Processing · Electrical Eng. & Systems 2020-02-28 Shen Wang , Kongming Liang , Chengwei Pan , Chuyang Ye , Xiuli Li , Feng Liu , Yizhou Yu , Yizhou Wang

Bayesian optimal experimental design (BOED) seeks to maximize the expected information gain (EIG) of experiments. This requires a likelihood estimate, which in many settings is intractable. Simulation-based inference (SBI) provides powerful…

Machine Learning · Computer Science 2026-02-09 Samuel Klein , Willie Neiswanger , Daniel Ratner , Michael Kagan , Sean Gasiorowski

Cortical visual prostheses aim to restore sight by electrically stimulating neurons in early visual cortex (V1). With the emergence of high-density and flexible neural interfaces, electrode placement within three-dimensional cortex has…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Galen Pogoncheff , Alvin Wang , Jacob Granley , Michael Beyeler

This work extends the results of [Garde and Hyv\"onen, Math. Comp. 91:1925-1953] on series reversion for Calder\'on's problem to the case of realistic electrode measurements, with both the internal admittivity of the investigated body and…

Numerical Analysis · Mathematics 2023-07-19 Henrik Garde , Nuutti Hyvönen , Topi Kuutela

For many years now, understanding the brain mechanism has been a great research subject in many different fields. Brain signal processing and especially electroencephalogram (EEG) has recently known a growing interest both in academia and…

Neurons and Cognition · Quantitative Biology 2022-04-18 Victor Delvigne , Hazem Wannous , Jean-Philippe Vandeborre , Laurence Ris , Thierry Dutoit