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This dissertation investigates privacy-preserving federated learning for Alzheimer's disease classification using three-dimensional MRI data from the Alzheimer's Disease Neuroimaging Initiative (ADNI). Existing methodologies often suffer…

Machine Learning · Computer Science 2026-03-18 Tin Hoang

This research work introduces a novel approach to the classification of Alzheimer's disease by using the advanced deep learning techniques combined with secure data processing methods. This research work primary uses transfer learning…

Image and Video Processing · Electrical Eng. & Systems 2024-11-21 Rishit Kapoor , Jesher Joshua , Muralidharan Vijayarangan , Natarajan B

Large volumes of medical data remain underutilized because centralizing distributed data is often infeasible due to strict privacy regulations and institutional constraints. In addition, models trained in centralized settings frequently…

Image and Video Processing · Electrical Eng. & Systems 2026-05-12 Puja Saha , Eranga Ukwatta

Privacy data protection in the medical field poses challenges to data sharing, limiting the ability to integrate data across hospitals for training high-precision auxiliary diagnostic models. Traditional centralized training methods are…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Tian Bowen , Xu Zhengyang , Yin Zhihao , Wang Jingying , Yue Yutao

Dementia, a neurological disorder impacting millions globally, presents significant challenges in diagnosis and patient care. With the rise of privacy concerns and security threats in healthcare, federated learning (FL) has emerged as a…

Cryptography and Security · Computer Science 2025-08-26 Gazi Tanbhir , Md. Farhan Shahriyar

The early-stage Alzheimer's disease (AD) detection has been considered an important field of medical studies. Like traditional machine learning methods, speech-based automatic detection also suffers from data privacy risks because the data…

Audio and Speech Processing · Electrical Eng. & Systems 2023-11-23 Wenqing Wei , Zhengdong Yang , Yuan Gao , Jiyi Li , Chenhui Chu , Shogo Okada , Sheng Li

The amount of biomedical data continues to grow rapidly. However, collecting data from multiple sites for joint analysis remains challenging due to security, privacy, and regulatory concerns. To overcome this challenge, we use Federated…

Distributed training can facilitate the processing of large medical image datasets, and improve the accuracy and efficiency of disease diagnosis while protecting patient privacy, which is crucial for achieving efficient medical image…

Image and Video Processing · Electrical Eng. & Systems 2024-04-17 Lisang Zhou , Meng Wang , Ning Zhou

The proliferation of deep learning applications in healthcare calls for data aggregation across various institutions, a practice often associated with significant privacy concerns. This concern intensifies in medical image analysis, where…

Machine Learning · Computer Science 2023-07-03 Kishore Babu Nampalle , Pradeep Singh , Uppala Vivek Narayan , Balasubramanian Raman

Machine Learning (ML) algorithms are generally designed for scenarios in which all data is stored in one data center, where the training is performed. However, in many applications, e.g., in the healthcare domain, the training data is…

Machine Learning · Computer Science 2024-09-16 Amin Aminifar , Matin Shokri , Amir Aminifar

Early diagnosis of Alzheimer's Disease (AD) is crucial for delaying its progression. While AI-based speech detection is non-invasive and cost-effective, it faces a critical data efficiency dilemma due to medical data scarcity and privacy…

Computation and Language · Computer Science 2026-02-17 Xiao Wei , Bin Wen , Yuqin Lin , Kai Li , Mingyang gu , Xiaobao Wang , Longbiao Wang , Jianwu Dang

Objective: To enable privacy-preserving learning of high quality generative and discriminative machine learning models from distributed electronic health records. Methods and Results: We describe general and scalable strategy to build…

Cryptography and Security · Computer Science 2018-06-19 Marina Blanton , Ah Reum Kang , Subhadeep Karan , Jaroslaw Zola

Machine learning (ML) and Artificial Intelligence (AI) have fueled remarkable advancements, particularly in healthcare. Within medical imaging, ML models hold the promise of improving disease diagnoses, treatment planning, and…

Machine Learning · Computer Science 2024-06-19 Nikolas Koutsoubis , Yasin Yilmaz , Ravi P. Ramachandran , Matthew Schabath , Ghulam Rasool

Parkinson's disease (PD) is a neurological disorder impacting a person's speech. Among automatic PD assessment methods, deep learning models have gained particular interest. Recently, the community has explored cross-pathology and…

Audio and Speech Processing · Electrical Eng. & Systems 2023-08-22 Soroosh Tayebi Arasteh , Cristian David Rios-Urrego , Elmar Noeth , Andreas Maier , Seung Hee Yang , Jan Rusz , Juan Rafael Orozco-Arroyave

Alzheimers Disease (AD) is a progressive neurodegenerative disorder that poses significant challenges in its early diagnosis, often leading to delayed treatment and poorer outcomes for patients. Traditional diagnostic methods, typically…

Machine Learning · Computer Science 2025-08-06 Tatwadarshi P Nagarhalli , Sanket Patil , Vishal Pande , Uday Aswalekar , Prafulla Patil

We propose a novel federated learning paradigm to model data variability among heterogeneous clients in multi-centric studies. Our method is expressed through a hierarchical Bayesian latent variable model, where client-specific parameters…

Machine Learning · Computer Science 2023-06-29 Irene Balelli , Santiago Silva , Marco Lorenzi

Federated learning enables training a global machine learning model from data distributed across multiple sites, without having to move the data. This is particularly relevant in healthcare applications, where data is rife with personal,…

Cryptography and Security · Computer Science 2020-02-24 Olivia Choudhury , Aris Gkoulalas-Divanis , Theodoros Salonidis , Issa Sylla , Yoonyoung Park , Grace Hsu , Amar Das

Leveraging real-world health data for machine learning tasks requires addressing many practical challenges, such as distributed data silos, privacy concerns with creating a centralized database from person-specific sensitive data, resource…

Machine Learning · Computer Science 2020-02-28 Olivia Choudhury , Aris Gkoulalas-Divanis , Theodoros Salonidis , Issa Sylla , Yoonyoung Park , Grace Hsu , Amar Das

Federated Learning (FL) is a distributed machine learning approach that safeguards privacy by creating an impartial global model while respecting the privacy of individual client data. However, the conventional FL method can introduce…

Machine Learning · Computer Science 2025-10-09 Muhammad Irfan Khan , Esa Alhoniemi , Elina Kontio , Suleiman A. Khan , Mojtaba Jafaritadi

Due to medical data privacy regulations, it is often infeasible to collect and share patient data in a centralised data lake. This poses challenges for training machine learning algorithms, such as deep convolutional networks, which often…

Computer Vision and Pattern Recognition · Computer Science 2019-10-03 Wenqi Li , Fausto Milletarì , Daguang Xu , Nicola Rieke , Jonny Hancox , Wentao Zhu , Maximilian Baust , Yan Cheng , Sébastien Ourselin , M. Jorge Cardoso , Andrew Feng
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