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Ptychography is a promising phase retrieval technique for label-free quantitative phase imaging. Recent advances in phase retrieval algorithms witnessed the development of spectral methods, in order to accelerate gradient descent…

Optics · Physics 2021-04-07 Lorenzo Valzania , Jonathan Dong , Sylvain Gigan

Cryo-electron microscopy (EM) single particle reconstruction is an entirely general technique for 3D structure determination of macromolecular complexes. However, because the images are taken at low electron dose, it is extremely hard to…

Computer Vision and Pattern Recognition · Computer Science 2019-04-17 Yifeng Fan , Zhizhen Zhao

Cryogenic electron tomography is a technique for imaging biological samples in 3D. A microscope collects a series of 2D projections of the sample, and the goal is to reconstruct the 3D density of the sample called the tomogram.…

Computer Vision and Pattern Recognition · Computer Science 2024-08-13 Simon Wiedemann , Reinhard Heckel

In Bragg Coherent Diffraction Imaging (BCDI), Phase Retrieval of highly strained crystals is often challenging with standard iterative algorithms. This computational obstacle limits the potential of the technique as it precludes the…

We introduce ICE-TIDE, a method for cryogenic electron tomography (cryo-ET) that simultaneously aligns observations and reconstructs a high-resolution volume. The alignment of tilt series in cryo-ET is a major problem limiting the…

Image and Video Processing · Electrical Eng. & Systems 2024-12-16 Valentin Debarnot , Vinith Kishore , Ricardo D. Righetto , Ivan Dokmanić

Phase retrieval is a well known ill-posed inverse problem where one tries to recover images given only the magnitude values of their Fourier transform as input. In recent years, new algorithms based on deep learning have been proposed,…

Image and Video Processing · Electrical Eng. & Systems 2022-04-21 Leon Gugel , Shai Dekel

Modern electron tomography has progressed to higher resolution at lower doses by leveraging compressed sensing methods that minimize total variation (TV). However, these sparsity-emphasized reconstruction algorithms introduce tunable…

Medical Physics · Physics 2023-09-12 William Millsaps , Jonathan Schwartz , Zichao Wendy Di , Yi Jiang , Robert Hovden

Electron cryomicroscopy (cryo-EM) is a technique in structural biology used to reconstruct accurate volumetric maps of molecules. One step of the cryo-EM pipeline involves solving an inverse-problem. This inverse-problem, referred to as…

Quantitative Methods · Quantitative Biology 2024-11-26 Aaditya V. Rangan , Wai-Shing Tang , Pilar Cossio , Kexin Zhang , Nikolaus Grigorieff

Ptychography is an imaging technique in which a localized illumination scans overlapping regions of an object and generates a set of diffraction intensities used to computationally reconstruct its complex-valued transmission function. We…

Quantum Physics · Physics 2019-12-18 Mário Foganholi Fernandes , Leonardo Neves

Multislice electron ptychography (MEP) is an inverse imaging technique that computationally reconstructs the highest-resolution images of atomic crystal structures from diffraction patterns. Available algorithms often solve this inverse…

Image and Video Processing · Electrical Eng. & Systems 2025-07-28 Christian K. Belardi , Chia-Hao Lee , Yingheng Wang , Justin Lovelace , Kilian Q. Weinberger , David A. Muller , Carla P. Gomes

Electron tomography, as an important 3D imaging method, offers a powerful method to probe the 3D structure of materials from the nano- to the atomic-scale. However, as a grant challenge, radiation intolerance of the nanoscale samples and…

Materials Science · Physics 2020-03-30 Chunyang Wang , Guanglei Ding , Yitong Liu , Huolin L. Xin

We present a proof-of-concept end-to-end system for computational extended depth of field (EDOF) imaging. The acquisition is performed through a phase-coded aperture implemented by placing a thin wavelength-dependent optical mask inside the…

Computer Vision and Pattern Recognition · Computer Science 2016-08-04 Tal Remez , Or Litany , Shachar Yoseff , Harel Haim , Alex Bronstein

To study the fundamental physics of complex multiphase flow systems using advanced measurement techniques, especially the electrical capacitance tomography (ECT) approach, this article carries out an initial literature review of the ECT…

Computer Vision and Pattern Recognition · Computer Science 2015-10-16 Kezhi Li

Demonstrating the utility of quantum algorithms is a long-standing challenge, where quantum machine learning becomes one of the most promising candidate that can be resorted to. In this study, we investigate a quantum neural compressive…

Quantum Physics · Physics 2025-02-26 Xinliang Zhai , Tailong Xiao , Jingzheng Huang , Jianping Fan , Guihua Zeng

Fast and accurate MRI reconstruction is a key concern in modern clinical practice. Recently, numerous Deep-Learning methods have been proposed for MRI reconstruction, however, they usually fail to reconstruct sharp details from the…

Image and Video Processing · Electrical Eng. & Systems 2023-06-21 Hanhui Yang , Juncheng Li , Lok Ming Lui , Shihui Ying , Jun Shi , Tieyong Zeng

Deep learning has demonstrated superb efficacy in processing imaging data, yet its suitability in solving challenging inverse problems in scientific imaging has not been fully explored. Of immense interest is the determination of local…

Materials Science · Physics 2019-02-20 Nouamane Laanait , Qian He , Albina Y. Borisevich

Astronomical images are often plagued by unwanted artifacts that arise from a number of sources including imperfect optics, faulty image sensors, cosmic ray hits, and even airplanes and artificial satellites. Spurious reflections (known as…

Instrumentation and Methods for Astrophysics · Physics 2021-05-28 Chihway Chang , Alex Drlica-Wagner , Stephen M. Kent , Brian Nord , Donah Michelle Wang , Michael H. L. S. Wang

In cryo-electron microscopy (EM), molecular structures are determined from large numbers of projection images of individual particles. To harness the full power of this single-molecule information, we use the Bayesian inference of EM…

Biomolecules · Quantitative Biology 2018-01-17 Pilar Cossio , David Rohr , Fabio Baruffa , Markus Rampp , Volker Lindenstruth , Gerhard Hummer

Computed Tomography (CT) image reconstruction is crucial for accurate diagnosis and deep learning approaches have demonstrated significant potential in improving reconstruction quality. However, the choice of loss function profoundly…

Image and Video Processing · Electrical Eng. & Systems 2024-03-19 Yipeng Sun , Yixing Huang , Linda-Sophie Schneider , Mareike Thies , Mingxuan Gu , Siyuan Mei , Siming Bayer , Andreas Maier

Biodegradable elastic scaffolds have attracted more and more attention in the field of soft tissue repair and tissue engineering. These scaffolds made of porous bioelastomers support tissue ingrowth along with their own degradation. It is…

Image and Video Processing · Electrical Eng. & Systems 2022-02-01 Dun Wang , Kaixuan Guo , Yanying Zhu , Jia Sun , Aliona Dreglea , Jiao Yu