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Reliable motion estimation and strain analysis using 3D+time echocardiography (4DE) for localization and characterization of myocardial injury is valuable for early detection and targeted interventions. However, motion estimation is…

The success of neural networks comes hand in hand with a desire for more interpretability. We focus on text classifiers and make them more interpretable by having them provide a justification, a rationale, for their predictions. We approach…

Computation and Language · Computer Science 2020-06-22 Jasmijn Bastings , Wilker Aziz , Ivan Titov

Interpretability is highly desired for deep neural network-based classifiers, especially when addressing high-stake decisions in medical imaging. Commonly used post-hoc interpretability methods have the limitation that they can produce…

Image and Video Processing · Electrical Eng. & Systems 2024-01-04 Sourya Sengupta , Mark A. Anastasio

Deep neural network models have been proven to be very successful in image classification tasks, also for medical diagnosis, but their main concern is its lack of interpretability. They use to work as intuition machines with high…

Machine Learning · Computer Science 2019-04-26 Jordi de la Torre , Aida Valls , Domenec Puig

Pathology plays an important role in disease diagnosis, treatment decision-making and drug development. Previous works on interpretability for machine learning models on pathology images have revolved around methods such as attention value…

Variational Autoencoders (VAEs) are powerful generative models for learning latent representations. Standard VAEs generate dispersed and unstructured latent spaces by utilizing all dimensions, which limits their interpretability, especially…

Computer Vision and Pattern Recognition · Computer Science 2025-05-21 Farshad Sangari Abiz , Reshad Hosseini , Babak N. Araabi

Finding an interpretable non-redundant representation of real-world data is one of the key problems in Machine Learning. Biological neural networks are known to solve this problem quite well in unsupervised manner, yet unsupervised…

Machine Learning · Computer Science 2020-10-13 Denis Kuzminykh , Laida Kushnareva , Timofey Grigoryev , Alexander Zatolokin

Prostate cancer being one of the frequently diagnosed malignancy in men, the rising demand for biopsies places a severe workload on pathologists. The grading procedure is tedious and subjective, motivating the development of automated…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Riddhasree Bhattacharyya , Pallabi Dutta , Sushmita Mitra

Deep learning shows promise for medical image analysis but lacks interpretability, hindering adoption in healthcare. Attribution techniques that explain model reasoning may increase trust in deep learning among clinical stakeholders. This…

Machine Learning · Computer Science 2023-08-08 Yusuf Brima , Marcellin Atemkeng

The use of wearables in medicine and wellness, enabled by AI-based models, offers tremendous potential for real-time monitoring and interpretable event detection. Explainable AI (XAI) is required to assess what models have learned and build…

Signal Processing · Electrical Eng. & Systems 2026-03-16 Maurice Kuschel , Solveig Vieluf , Claus Reinsberger , Tobias Loddenkemper , Tanuj Hasija

Unsupervised Anomaly Detection has become a popular method to detect pathologies in medical images as it does not require supervision or labels for training. Most commonly, the anomaly detection model generates a "normal" version of an…

Image and Video Processing · Electrical Eng. & Systems 2023-09-26 Felix Meissen , Johannes Paetzold , Georgios Kaissis , Daniel Rueckert

In the recent years, convolutional neural networks have transformed the field of medical image analysis due to their capacity to learn discriminative image features for a variety of classification and regression tasks. However, successfully…

Computer Vision and Pattern Recognition · Computer Science 2019-07-08 Wenjia Bai , Chen Chen , Giacomo Tarroni , Jinming Duan , Florian Guitton , Steffen E. Petersen , Yike Guo , Paul M. Matthews , Daniel Rueckert

Interpretability and small labelled datasets are key issues in the practical application of deep learning, particularly in areas such as medicine. In this paper, we present a semi-supervised technique that addresses both these issues by…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 Jarrel Seah , Jennifer Tang , Andy Kitchen , Jonathan Seah

The autoencoder is an unsupervised learning paradigm that aims to create a compact latent representation of data by minimizing the reconstruction loss. However, it tends to overlook the fact that most data (images) are embedded in a…

Machine Learning · Computer Science 2023-10-26 Alokendu Mazumder , Tirthajit Baruah , Bhartendu Kumar , Rishab Sharma , Vishwajeet Pattanaik , Punit Rathore

Accurate prediction of cardiovascular diseases remains imperative for early diagnosis and intervention, necessitating robust and precise predictive models. Recently, there has been a growing interest in multi-modal learning for uncovering…

Computer Vision and Pattern Recognition · Computer Science 2024-11-12 Francesco Girlanda , Olga Demler , Bjoern Menze , Neda Davoudi

Interpretability methods aim to help users build trust in and understand the capabilities of machine learning models. However, existing approaches often rely on abstract, complex visualizations that poorly map to the task at hand or require…

Human-Computer Interaction · Computer Science 2021-07-12 Harini Suresh , Kathleen M. Lewis , John V. Guttag , Arvind Satyanarayan

Clinical decision making is challenging because of pathological complexity, as well as large amounts of heterogeneous data generated as part of routine clinical care. In recent years, machine learning tools have been developed to aid this…

With recent progress on fine-tuning language models around a fixed sparse autoencoder, we disentangle the decoder matrix into almost orthogonal features. This reduces interference and superposition between the features, while keeping…

Machine Learning · Computer Science 2026-02-05 Moritz Miller , Florent Draye , Bernhard Schölkopf

Interpretability allows the domain-expert to directly evaluate the model's relevance and reliability, a practice that offers assurance and builds trust. In the healthcare setting, interpretable models should implicate relevant biological…

Machine Learning · Computer Science 2020-06-18 Thomas P. Quinn , Dang Nguyen , Santu Rana , Sunil Gupta , Svetha Venkatesh

The fields of explainable AI and mechanistic interpretability aim to uncover the internal structure of neural networks, with circuit discovery as a central tool for understanding model computations. Existing approaches, however, rely on…

Machine Learning · Computer Science 2026-03-05 Elena Golimblevskaia , Aakriti Jain , Bruno Puri , Ammar Ibrahim , Wojciech Samek , Sebastian Lapuschkin