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Many domains now leverage the benefits of Machine Learning (ML), which promises solutions that can autonomously learn to solve complex tasks by training over some data. Unfortunately, in cyberthreat detection, high-quality data is hard to…

Cryptography and Security · Computer Science 2023-12-12 Tobias Braun , Irdin Pekaric , Giovanni Apruzzese

A plethora of protein language models have been released in recent years. Yet comparatively little work has addressed how to best sample from them to optimize desired biological properties. We fill this gap by proposing a flexible,…

Machine Learning · Computer Science 2026-05-08 Calvin McCarter , Nick Bhattacharya , Sebastian W. Ober , Hunter Elliott

Machine learning (ML) is increasingly being adopted in a wide variety of application domains. Usually, a well-performing ML model relies on a large volume of training data and high-powered computational resources. Such a need for and the…

Machine Learning · Computer Science 2021-09-23 Runhua Xu , Nathalie Baracaldo , James Joshi

Machine learning (ML) is becoming increasingly crucial in many fields of engineering but has not yet played out its full potential in bioprocess engineering. While experimentation has been accelerated by increasing levels of lab automation,…

With the development of computer-assisted techniques, research communities including biochemistry and deep learning have been devoted into the drug discovery field for over a decade. Various applications of deep learning have drawn great…

Machine Learning · Computer Science 2023-03-07 Wenhao Hu , Yingying Liu , Xuanyu Chen , Wenhao Chai , Hangyue Chen , Hongwei Wang , Gaoang Wang

A clinical trial is an essential step in drug development, which is often costly and time-consuming. In silico trials are clinical trials conducted digitally through simulation and modeling as an alternative to traditional clinical trials.…

Quantitative Methods · Quantitative Biology 2022-09-20 Zifeng Wang , Chufan Gao , Lucas M. Glass , Jimeng Sun

The problem of malicious software (malware) detection and classification is a complex task, and there is no perfect approach. There is still a lot of work to be done. Unlike most other research areas, standard benchmarks are difficult to…

Cryptography and Security · Computer Science 2024-07-30 Ahmed Bensaoud , Jugal Kalita , Mahmoud Bensaoud

In the past decade, considerable research effort has been devoted to securing machine learning (ML) models that operate in adversarial settings. Yet, progress has been slow even for simple "toy" problems (e.g., robustness to small…

Machine Learning · Computer Science 2025-02-05 Javier Rando , Jie Zhang , Nicholas Carlini , Florian Tramèr

In this survey, we discuss the challenges of executing scientific workflows as well as existing Machine Learning (ML) techniques to alleviate those challenges. We provide the context and motivation for applying ML to each step of the…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-10-28 Azita Nouri , Philip E. Davis , Pradeep Subedi , Manish Parashar

Machine learning-based medical anomaly detection is an important problem that has been extensively studied. Numerous approaches have been proposed across various medical application domains and we observe several similarities across these…

Machine Learning · Computer Science 2021-04-14 Tharindu Fernando , Harshala Gammulle , Simon Denman , Sridha Sridharan , Clinton Fookes

The US Food and Drug Administration (FDA) has been actively promoting the use of real-world data (RWD) in drug development. RWD can generate important real-world evidence reflecting the real-world clinical environment where the treatments…

Computers and Society · Computer Science 2021-02-03 Zhaoyi Chen , Xiong Liu , William Hogan , Elizabeth Shenkman , Jiang Bian

Machine learning (ML) provides a broad spectrum of tools and architectures that enable the transformation of data from simulations and experiments into useful and explainable science, thereby augmenting domain knowledge. Furthermore,…

Plasma Physics · Physics 2024-09-05 Farbod Faraji , Maryam Reza

Artificial intelligence (AI) and machine learning (ML) are increasingly broadly adopted in industry, However, based on well over a dozen case studies, we have learned that deploying industry-strength, production quality ML models in systems…

Machine Learning · Computer Science 2020-06-04 Jan Bosch , Ivica Crnkovic , Helena Holmström Olsson

Machine Learning (ML) is currently being exploited in numerous applications being one of the most effective Artificial Intelligence (AI) technologies, used in diverse fields, such as vision, autonomous systems, and alike. The trend…

Machine Learning · Computer Science 2024-05-31 Cristiana Bolchini , Luca Cassano , Antonio Miele

Prediction of diabetes and its various complications has been studied in a number of settings, but a comprehensive overview of problem setting for diabetes prediction and care management has not been addressed in the literature. In this…

Machine Learning · Computer Science 2021-04-30 Aloysius Lim , Ashish Singh , Jody Chiam , Carly Eckert , Vikas Kumar , Muhammad Aurangzeb Ahmad , Ankur Teredesai

Current pharmaceutical formulation development still strongly relies on the traditional trial-and-error approach by individual experiences of pharmaceutical scientists, which is laborious, time-consuming and costly. Recently, deep learning…

Machine Learning · Computer Science 2018-12-05 Yilong Yang , Zhuyifan Ye , Yan Su , Qianqian Zhao , Xiaoshan Li , Defang Ouyang

Machine learning (ML) is the fastest growing field in computer science and healthcare, providing future benefits in improved medical diagnoses, disease analyses and prevention. In this paper, we introduce an application of interactive…

Computers and Society · Computer Science 2018-03-07 Ahmed Fadhil

Adversarial phenomenon has been widely observed in machine learning (ML) systems, especially in those using deep neural networks, describing that ML systems may produce inconsistent and incomprehensible predictions with humans at some…

Computer Vision and Pattern Recognition · Computer Science 2023-12-15 Baoyuan Wu , Shaokui Wei , Mingli Zhu , Meixi Zheng , Zihao Zhu , Mingda Zhang , Hongrui Chen , Danni Yuan , Li Liu , Qingshan Liu

The idea of applying machine learning(ML) to solve problems in security domains is almost 3 decades old. As information and communications grow more ubiquitous and more data become available, many security risks arise as well as appetite to…

Cryptography and Security · Computer Science 2016-11-11 Heju Jiang , Jasvir Nagra , Parvez Ahammad

Machine learning (ML) is a subfield of Artificial intelligence (AI), and its applications in radiology are growing at an ever-accelerating rate. The most studied ML application is the automated interpretation of images. However, natural…

Computer Vision and Pattern Recognition · Computer Science 2022-06-24 Nihal Raju , Michael Woodburn , Stefan Kachel , Jack O'Shaughnessy , Laurence Sorace , Natalie Yang , Ruth P Lim