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Machine learning models, particularly deep neural networks, have demonstrated strong performance in classifying complex time series data. However, their black-box nature limits trust and adoption, especially in high-stakes domains such as…

Machine Learning · Computer Science 2025-12-23 Justin Li , Efe Sencan , Jasper Zheng Duan , Vitus J. Leung , Stephen Tsaur , Ayse K. Coskun

The recent prevalence of publicly accessible, large medical imaging datasets has led to a proliferation of artificial intelligence (AI) models for cardiovascular image classification and analysis. At the same time, the potentially…

Human-Computer Interaction · Computer Science 2024-04-26 Grace Guo , Lifu Deng , Animesh Tandon , Alex Endert , Bum Chul Kwon

Electrocardiogram (ECG) is essential for the clinical diagnosis of arrhythmias and other heart diseases, but deep learning methods based on ECG often face limitations due to the need for high-quality annotations. Although previous ECG…

Machine Learning · Computer Science 2025-02-18 Jiarui Jin , Haoyu Wang , Hongyan Li , Jun Li , Jiahui Pan , Shenda Hong

Development of interpretable machine learning models for clinical healthcare applications has the potential of changing the way we understand, treat, and ultimately cure, diseases and disorders in many areas of medicine. These models can…

Machine Learning · Computer Science 2019-08-06 Qingzhu Gao , Humberto Gonzalez , Parvez Ahammad

Counterfactual Explanation (CE) techniques have garnered attention as a means to provide insights to the users engaging with AI systems. While extensively researched in domains such as medical imaging and autonomous vehicles, Graph…

Machine Learning · Computer Science 2024-01-12 Mario Alfonso Prado-Romero , Bardh Prenkaj , Giovanni Stilo

Rapid improvements in the performance of machine learning models have pushed them to the forefront of data-driven decision-making. Meanwhile, the increased integration of these models into various application domains has further highlighted…

Human-Computer Interaction · Computer Science 2021-09-14 Oscar Gomez , Steffen Holter , Jun Yuan , Enrico Bertini

Counterfactual prediction methods are required when a model will be deployed in a setting where treatment policies differ from the setting where the model was developed, or when a model provides predictions under hypothetical interventions…

Methodology · Statistics 2025-08-13 Christopher B. Boyer , Issa J. Dahabreh , Jon A. Steingrimsson

Electrocardiogram (ECG) signal is a common and powerful tool to study heart function and diagnose several abnormal arrhythmias. While there have been remarkable improvements in cardiac arrhythmia classification methods, they still cannot…

Quantitative Methods · Quantitative Biology 2019-03-14 Sajad Mousavi , Fatemeh Afghah , U. Rajendra Acharya

Advancements in deep learning have enabled highly accurate arrhythmia detection from electrocardiogram (ECG) signals, but limited interpretability remains a barrier to clinical adoption. This study investigates the application of…

Machine Learning · Computer Science 2025-08-26 Joschka Beck , Arlene John

The classification of electrocardiogram (ECG) signals is crucial for early detection of arrhythmias and other cardiac conditions. However, despite advances in machine learning, many studies fail to follow standardization protocols, leading…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Guilherme Silva , Pedro Silva , Gladston Moreira , Vander Freitas , Jadson Gertrudes , Eduardo Luz

Structural heart disease (SHD) is a prevalent condition with many undiagnosed cases, and early detection is often limited by the high cost and accessibility constraints of echocardiography (ECHO). Recent studies show that artificial…

Applications · Statistics 2026-03-04 Ya Zhou , Zhaohong Sun , Tianxiang Hao , Xiangjie Li

Cardiac arrhythmia is a prevalent and significant cause of morbidity and mortality among cardiac ailments. Early diagnosis is crucial in providing intervention for patients suffering from cardiac arrhythmia. Traditionally, diagnosis is…

Signal Processing · Electrical Eng. & Systems 2020-04-14 Sricharan Vijayarangan , Balamurali Murugesan , Vignesh R , Preejith SP , Jayaraj Joseph , Mohansankar Sivaprakasam

A comprehensive survey revealed that many patients of Acute Myocardial Infarction reach to the hospital so late to deliver an effective treatment. This leads to poor treatment outcome which increases the mortality rates. Multiple reasons…

Signal Processing · Electrical Eng. & Systems 2018-05-16 Masoud Elhami Asl , Masoomeh Rahimpour , Mahmoud Reza Merati , Amir Hossein Panahi , Kamran Gholami

Counterfactual explanations (CFE) for deep image classifiers aim to reveal how minimal input changes lead to different model decisions, providing critical insights for model interpretation and improvement. However, existing CFE methods…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Townim Faisal Chowdhury , Vu Minh Hieu Phan , Kewen Liao , Nanyu Dong , Minh-Son To , Anton Hengel , Johan Verjans , Zhibin Liao

Counterfactual explanations play an important role in detecting bias and improving the explainability of data-driven classification models. A counterfactual explanation (CE) is a minimal perturbed data point for which the decision of the…

Machine Learning · Computer Science 2023-10-27 Donato Maragno , Jannis Kurtz , Tabea E. Röber , Rob Goedhart , Ş. Ilker Birbil , Dick den Hertog

Counterfactual explanations (CEs) enhance the interpretability of machine learning models by describing what changes to an input are necessary to change its prediction to a desired class. These explanations are commonly used to guide users'…

Machine Learning · Computer Science 2024-03-07 Anna P. Meyer , Yuhao Zhang , Aws Albarghouthi , Loris D'Antoni

Machine learning plays a role in many deployed decision systems, often in ways that are difficult or impossible to understand by human stakeholders. Explaining, in a human-understandable way, the relationship between the input and output of…

Machine Learning · Computer Science 2022-11-17 Sahil Verma , Varich Boonsanong , Minh Hoang , Keegan E. Hines , John P. Dickerson , Chirag Shah

In real-world clinical practice, electrocardiograms (ECGs) are often captured and shared as photographs. However, publicly available ECG data, and thus most related research, relies on digital signals. This has led to a disconnect in which…

Computer Vision and Pattern Recognition · Computer Science 2025-12-25 Xiaoyu Wang , Ramesh Nadarajah , Zhiqiang Zhang , David Wong

Myocardial Contrast Echocardiography (MCE) with micro-bubble contrast agent enables myocardial perfusion quantification which is invaluable for the early detection of coronary artery diseases. In this paper, we proposed a new segmentation…

Computer Vision and Pattern Recognition · Computer Science 2018-06-21 Yuanwei Li , Chin Pang Ho , Navtej Chahal , Roxy Senior , Meng-Xing Tang

Cardiac indices estimation is of great importance during identification and diagnosis of cardiac disease in clinical routine. However, estimation of multitype cardiac indices with consistently reliable and high accuracy is still a great…

Computer Vision and Pattern Recognition · Computer Science 2017-05-29 Wufeng Xue , Ali Islam , Mousumi Bhaduri , Shuo Li