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With the development of deep learning-based methods, automated classification of electrocardiograms (ECGs) has recently gained much attention. Although the effectiveness of deep neural networks has been encouraging, the lack of information…

Signal Processing · Electrical Eng. & Systems 2022-03-02 Wenrui Zhang , Xinxin Di , Guodong Wei , Shijia Geng , Zhaoji Fu , Shenda Hong

Cardiac magnetic resonance imaging (CMR) offers detailed evaluation of cardiac structure and function, but its limited accessibility restricts use to selected patient populations. In contrast, the electrocardiogram (ECG) is ubiquitous and…

Recognizing the need for explainable AI (XAI) approaches to enable the successful integration of AI-based ECG prediction models (AI-ECG) into clinical practice, we introduce a framework generating \textbf{Co}unter\textbf{F}actual…

Artificial Intelligence · Computer Science 2025-08-25 Jong-Hwan Jang , Junho Song , Yong-Yeon Jo

Cardiac digital twins (CDTs) have the potential to offer individualized evaluation of cardiac function in a non-invasive manner, making them a promising approach for personalized diagnosis and treatment planning of my-ocardial infarction…

Signal Processing · Electrical Eng. & Systems 2024-02-16 Lei Li , Julia Camps , Zhinuo , Wang , Abhirup Banerjee , Marcel Beetz , Blanca Rodriguez , Vicente Grau

High-fidelity ECG interpretation is increasingly reliant on massive foundation models, yet their deployment in clinical edge-care remains hindered by extreme computational demands. While knowledge distillation (KD) is a promising solution,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-29 Dang Hong Nguyen , Nhi Ngoc-Yen Nguyen , Huy-Hieu Pham

The electrocardiogram or ECG has been in use for over 100 years and remains the most widely performed diagnostic test to characterize cardiac structure and electrical activity. We hypothesized that parallel advances in computing power,…

Computer Vision and Pattern Recognition · Computer Science 2018-07-10 Geoffrey H. Tison , Jeffrey Zhang , Francesca N. Delling , Rahul C. Deo

Accurate localization of myocardial infarction is essential for risk stratification. While LGE-MRI remains the gold standard, it is resource-intensive. Integrating cine MRI with ECG enables a more detailed representation of infarct…

Computer Vision and Pattern Recognition · Computer Science 2026-05-22 Mengxiao Wang , Yilin Lyu , Julia Camps , Ching Hui Sia , Mark Yan-Yee Chan , Yanrui Jin , Shuzhi Sam Ge , Chengliang Liu , Lei Li

Purpose: Chest X-rays are essential for diagnosing pulmonary conditions, but limited access in resource-constrained settings can delay timely diagnosis. Electrocardiograms (ECGs), in contrast, are widely available, non-invasive, and often…

Signal Processing · Electrical Eng. & Systems 2025-09-23 Julia Matejas , Olaf Żurawski , Nils Strodthoff , Juan Miguel Lopez Alcaraz

Background: Neoplasms are a major cause of mortality globally, where early diagnosis is essential for improving outcomes. Current diagnostic methods are often invasive, expensive, and inaccessible in resource-limited settings. This study…

Signal Processing · Electrical Eng. & Systems 2025-11-21 Juan Miguel Lopez Alcaraz , Wilhelm Haverkamp , Nils Strodthoff

Automated electrocardiogram (ECG) classification is essential for early detection of cardiovascular diseases. While recent approaches have increasingly relied on deep neural networks with complex architectures, we demonstrate that careful…

Machine Learning · Computer Science 2026-03-10 Naqcho Ali Mehdi , Amir Ali

Deep learning has achieved expert-level performance in automated electrocardiogram (ECG) diagnosis, yet the "black-box" nature of these models hinders their clinical deployment. Trust in medical AI requires not just high accuracy but also…

Machine Learning · Computer Science 2026-02-11 Vajira Thambawita , Jonas L. Isaksen , Jørgen K. Kanters , Hugo L. Hammer , Pål Halvorsen

Electrocardiography (ECG) is a non-invasive tool for predicting cardiovascular diseases (CVDs). Current ECG-based diagnosis systems show promising performance owing to the rapid development of deep learning techniques. However, the label…

Signal Processing · Electrical Eng. & Systems 2023-06-21 Rushuang Zhou , Lei Lu , Zijun Liu , Ting Xiang , Zhen Liang , David A. Clifton , Yining Dong , Yuan-Ting Zhang

Deep learning has significantly advanced electrocardiogram (ECG) analysis, enabling automatic annotation, disease screening, and prognosis beyond traditional clinical capabilities. However, understanding these models remains a challenge,…

Machine Learning · Computer Science 2025-09-19 Ahcène Boubekki , Konstantinos Patlatzoglou , Joseph Barker , Fu Siong Ng , Antônio H. Ribeiro

Counterfactual explanation is a form of interpretable machine learning that generates perturbations on a sample to achieve the desired outcome. The generated samples can act as instructions to guide end users on how to observe the desired…

Machine Learning · Computer Science 2023-03-28 Tri Dung Duong , Qian Li , Guandong Xu

Echocardiography is essential to modern cardiology. However, human interpretation limits high throughput analysis, limiting echocardiography from reaching its full clinical and research potential for precision medicine. Deep learning is a…

Computer Vision and Pattern Recognition · Computer Science 2017-06-28 Ali Madani , Ramy Arnaout , Mohammad Mofrad , Rima Arnaout

The realisation of precision cardiology requires novel techniques for the non-invasive characterisation of individual patients' cardiac function to inform therapeutic and diagnostic decision-making. The electrocardiogram (ECG) is the most…

Tissues and Organs · Quantitative Biology 2021-12-09 Julia Camps , Brodie Lawson , Christopher Drovandi , Ana Minchole , Zhinuo Jenny Wang , Vicente Grau , Kevin Burrage , Blanca Rodriguez

Counterfactual inference provides a mathematical framework for reasoning about hypothetical outcomes under alternative interventions, bridging causal reasoning and predictive modeling. We present a counterfactual inference framework for…

Machine Learning · Computer Science 2025-10-22 Jingya Cheng , Alaleh Azhir , Jiazi Tian , Hossein Estiri

Visual counterfactual explainers (VCEs) are a straightforward and promising approach to enhancing the transparency of image classifiers. VCEs complement other types of explanations, such as feature attribution, by revealing the specific…

Machine Learning · Computer Science 2026-01-13 Sidney Bender , Jan Herrmann , Klaus-Robert Müller , Grégoire Montavon

Electrocardiogram (ECG) interpretation requires specialized expertise, often involving synthesizing insights from ECG signals with complex clinical queries posed in natural language. The scarcity of labeled ECG data coupled with the diverse…

Machine Learning · Computer Science 2025-05-09 Jialu Tang , Tong Xia , Yuan Lu , Cecilia Mascolo , Aaqib Saeed

Electrocardiogram is a useful diagnostic signal that can detect cardiac abnormalities by measuring the electrical activity generated by the heart. Due to its rapid, non-invasive, and richly informative characteristics, ECG has many emerging…

Machine Learning · Computer Science 2025-12-09 Hanhui Deng , Xinglin Li , Jie Luo , Di Wu