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Brain tissue segmentation has demonstrated great utility in quantifying MRI data through Voxel-Based Morphometry and highlighting subtle structural changes associated with various conditions within the brain. However, manual segmentation is…

Image and Video Processing · Electrical Eng. & Systems 2023-02-02 Vishwanatha M. Rao , Zihan Wan , Soroush Arabshahi , David J. Ma , Pin-Yu Lee , Ye Tian , Xuzhe Zhang , Andrew F. Laine , Jia Guo

Traditional neuroimage analysis pipelines involve computationally intensive, time-consuming optimization steps, and thus, do not scale well to large cohort studies with thousands or tens of thousands of individuals. In this work we propose…

Image and Video Processing · Electrical Eng. & Systems 2020-06-11 Leonie Henschel , Sailesh Conjeti , Santiago Estrada , Kersten Diers , Bruce Fischl , Martin Reuter

Widely used traditional pipelines for subcortical brain segmentation are often inefficient and slow, particularly when processing large datasets. Furthermore, deep learning models face challenges due to the high resolution of MRI images and…

Image and Video Processing · Electrical Eng. & Systems 2024-10-15 Aaron Cao , Zongyu Li , Jordan Jomsky , Andrew F. Laine , Jia Guo

The study of neurodegenerative diseases relies on the reconstruction and analysis of the brain cortex from magnetic resonance imaging (MRI). Traditional frameworks for this task like FreeSurfer demand lengthy runtimes, while its accelerated…

Image and Video Processing · Electrical Eng. & Systems 2020-10-23 Rodrigo Santa Cruz , Leo Lebrat , Pierrick Bourgeat , Clinton Fookes , Jurgen Fripp , Olivier Salvado

Sub-cortical brain structure segmentation in Magnetic Resonance Images (MRI) has attracted the interest of the research community for a long time because morphological changes in these structures are related to different neurodegenerative…

Computer Vision and Pattern Recognition · Computer Science 2018-11-15 Kaisar Kushibar , Sergi Valverde , Sandra Gonzalez-Villa , Jose Bernal , Mariano Cabezas , Arnau Oliver , Xavier Llado

The hypothalamus plays a crucial role in the regulation of a broad range of physiological, behavioural, and cognitive functions. However, despite its importance, only a few small-scale neuroimaging studies have investigated its…

Computer Vision and Pattern Recognition · Computer Science 2023-11-08 Santiago Estrada , David Kügler , Emad Bahrami , Peng Xu , Dilshad Mousa , Monique M. B. Breteler , N. Ahmad Aziz , Martin Reuter

In this paper we propose a deep learning approach for segmenting sub-cortical structures of the human brain in Magnetic Resonance (MR) image data. We draw inspiration from a state-of-the-art Fully-Convolutional Neural Network (F-CNN)…

Computer Vision and Pattern Recognition · Computer Science 2016-02-08 Mahsa Shakeri , Stavros Tsogkas , Enzo Ferrante , Sarah Lippe , Samuel Kadoury , Nikos Paragios , Iasonas Kokkinos

Many functional and structural neuroimaging studies call for accurate morphometric segmentation of different brain structures starting from image intensity values of MRI scans. Current automatic (multi-) atlas-based segmentation strategies…

Image and Video Processing · Electrical Eng. & Systems 2019-09-27 Dennis Bontempi , Sergio Benini , Alberto Signoroni , Michele Svanera , Lars Muckli

Accurate segmentation of tubular structures in medical images, such as vessels and airway trees, is crucial for computer-aided diagnosis, radiotherapy, and surgical planning. However, significant challenges exist in algorithm design when…

Image and Video Processing · Electrical Eng. & Systems 2025-04-11 Yi Huang , Ke Zhang , Wei Liu , Yuanyuan Wang , Vishal M. Patel , Le Lu , Xu Han , Dakai Jin , Ke Yan

Medical images used in clinical practice are heterogeneous and not the same quality as scans studied in academic research. Preprocessing breaks down in extreme cases when anatomy, artifacts, or imaging parameters are unusual or protocols…

Image and Video Processing · Electrical Eng. & Systems 2022-08-31 Mostafa Mehdipour Ghazi , Mads Nielsen

Quantitative, volumetric analysis of Magnetic Resonance Imaging (MRI) is a fundamental way researchers study the brain in a host of neurological conditions including normal maturation and aging. Despite the availability of open-source brain…

Quantitative Methods · Quantitative Biology 2019-11-15 Aakash Kaku , Chaitra V. Hegde , Jeffrey Huang , Sohae Chung , Xiuyuan Wang , Matthew Young , Alireza Radmanesh , Yvonne W. Lui , Narges Razavian

Deep learning has shown great potential for automated medical image segmentation to improve the precision and speed of disease diagnostics. However, the task presents significant difficulties due to variations in the scale, shape, texture,…

Image and Video Processing · Electrical Eng. & Systems 2024-09-06 Shahzaib Iqbal , Tariq M. Khan , Syed S. Naqvi , Asim Naveed , Erik Meijering

This study investigates a 3D and fully convolutional neural network (CNN) for subcortical brain structure segmentation in MRI. 3D CNN architectures have been generally avoided due to their computational and memory requirements during…

Computer Vision and Pattern Recognition · Computer Science 2017-04-21 J. Dolz , C. Desrosiers , I. Ben Ayed

Background: The hippocampus plays a crucial role in memory and cognition. Because of the associated toxicity from whole brain radiotherapy, more advanced treatment planning techniques prioritize hippocampal avoidance, which depends on an…

Medical Physics · Physics 2023-06-16 Yang Lei , Yifu Ding , Richard L. J. Qiu , Tonghe Wang , Justin Roper , Yabo Fu , Hui-Kuo Shu , Hui Mao , Xiaofeng Yang

Brains with complex distortion of cerebral anatomy present several challenges to automatic tissue segmentation methods of T1-weighted MR images. First, the very high variability in the morphology of the tissues can be incompatible with the…

Tissues and Organs · Quantitative Biology 2020-03-25 Gabriele Amorosino , Denis Peruzzo , Pietro Astolfi , Daniela Redaelli , Paolo Avesani , Filippo Arrigoni , Emanuele Olivetti

Segmenting deep brain structures from magnetic resonance images is important for patient diagnosis, surgical planning, and research. Most current state-of-the-art solutions follow a segmentation-by-registration approach, where subject MRIs…

Image and Video Processing · Electrical Eng. & Systems 2022-05-20 Mehri Baniasadi , Mikkel V. Petersen , Jorge Goncalves , Andreas Horn , Vanja Vlasov , Frank Hertel , Andreas Husch

Vascular segmentation represents a crucial clinical task, yet its automation remains challenging. Because of the recent strides in deep learning, vesselness filters, which can significantly aid the learning process, have been overlooked.…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Guillaume Garret , Antoine Vacavant , Carole Frindel

Deep learning approaches may help radiologists in the early diagnosis and timely treatment of cerebrovascular diseases. Accurate cerebral vessel segmentation of Time-of-Flight Magnetic Resonance Angiographs (TOF-MRAs) is an essential step…

Image and Video Processing · Electrical Eng. & Systems 2021-01-25 V. de Vos , K. M. Timmins , I. C. van der Schaaf , Y. Ruigrok , B. K. Velthuis , H. J. Kuijf

Catheter segmentation in 3D ultrasound is important for computer-assisted cardiac intervention. However, a large amount of labeled images are required to train a successful deep convolutional neural network (CNN) to segment the catheter,…

Image and Video Processing · Electrical Eng. & Systems 2020-06-29 Hongxu Yang , Caifeng Shan , Alexander F. Kolen , Peter H. N. de With

Automated blood vessel segmentation is vital for biomedical imaging, as vessel changes indicate many pathologies. Still, precise segmentation is difficult due to the complexity of vascular structures, anatomical variations across patients,…

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