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Diffusion probabilistic models have made their way into a number of high-profile applications since their inception. In particular, there has been a wave of research into using diffusion models in the prediction and design of biomolecular…

Biomolecules · Quantitative Biology 2024-06-05 Trevor Norton , Debswapna Bhattacharya

Denoising diffusions are state-of-the-art generative models exhibiting remarkable empirical performance. They work by diffusing the data distribution into a Gaussian distribution and then learning to reverse this noising process to obtain…

Machine Learning · Statistics 2024-02-20 Joe Benton , Yuyang Shi , Valentin De Bortoli , George Deligiannidis , Arnaud Doucet

In recent years, diffusion models, and more generally score-based deep generative models, have achieved remarkable success in various applications, including image and audio generation. In this paper, we view diffusion models as an implicit…

Statistics Theory · Mathematics 2026-02-12 Hyeok Kyu Kwon , Dongha Kim , Ilsang Ohn , Minwoo Chae

Curse of Dimensionality is an unavoidable challenge in statistical probability models, yet diffusion models seem to overcome this limitation, achieving impressive results in high-dimensional data generation. Diffusion models assume that…

Machine Learning · Statistics 2025-10-01 Zhenxin Zheng , Zhenjie Zheng

Denoising diffusion models have emerged as the go-to generative framework for solving inverse problems in imaging. A critical concern regarding these models is their performance on out-of-distribution tasks, which remains an under-explored…

Computer Vision and Pattern Recognition · Computer Science 2025-01-29 Riccardo Barbano , Alexander Denker , Hyungjin Chung , Tae Hoon Roh , Simon Arridge , Peter Maass , Bangti Jin , Jong Chul Ye

We propose a novel denoising diffusion generative model for predicting nonlinear fluid fields named FluidDiff. By performing a diffusion process, the model is able to learn a complex representation of the high-dimensional dynamic system,…

Machine Learning · Computer Science 2023-01-31 Gefan Yang , Stefan Sommer

Recently, diffusion model have demonstrated impressive image generation performances, and have been extensively studied in various computer vision tasks. Unfortunately, training and evaluating diffusion models consume a lot of time and…

Computer Vision and Pattern Recognition · Computer Science 2022-10-03 Dohoon Ryu , Jong Chul Ye

We introduce the state-of-the-art deep learning Denoising Diffusion Probabilistic Model (DDPM) as a method to infer the volume or number density of giant molecular clouds (GMCs) from projected mass surface density maps. We adopt…

Astrophysics of Galaxies · Physics 2023-06-28 Duo Xu , Jonathan C. Tan , Chia-Jung Hsu , Ye Zhu

Diffusion models have emerged as powerful tools for molecular generation, particularly in the context of 3D molecular structures. Inspired by non-equilibrium statistical physics, these models can generate 3D molecular structures with…

Chemical Physics · Physics 2025-05-16 Amira Alakhdar , Barnabas Poczos , Newell Washburn

Diffusion models (DMs) have recently been introduced in image deblurring and exhibited promising performance, particularly in terms of details reconstruction. However, the diffusion model requires a large number of inference iterations to…

Computer Vision and Pattern Recognition · Computer Science 2023-09-26 Zheng Chen , Yulun Zhang , Ding Liu , Bin Xia , Jinjin Gu , Linghe Kong , Xin Yuan

Image dehazing is quite challenging in dense-haze scenarios, where quite less original information remains in the hazy image. Though previous methods have made marvelous progress, they still suffer from information loss in content and color…

Computer Vision and Pattern Recognition · Computer Science 2024-04-16 Hu Yu , Jie Huang , Kaiwen Zheng , Feng Zhao

This paper addresses the challenging problem of category-level pose estimation. Current state-of-the-art methods for this task face challenges when dealing with symmetric objects and when attempting to generalize to new environments solely…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Takuya Ikeda , Sergey Zakharov , Tianyi Ko , Muhammad Zubair Irshad , Robert Lee , Katherine Liu , Rares Ambrus , Koichi Nishiwaki

Diffusion models have attained remarkable success in the domains of image generation and editing. It is widely recognized that employing larger inversion and denoising steps in diffusion model leads to improved image reconstruction quality.…

Computer Vision and Pattern Recognition · Computer Science 2024-01-05 Chen Hou , Guoqiang Wei , Zhibo Chen

Recently, research on denoising diffusion models has expanded its application to the field of image restoration. Traditional diffusion-based image restoration methods utilize degraded images as conditional input to effectively guide the…

Computer Vision and Pattern Recognition · Computer Science 2024-10-25 Zhenning Shi , Haoshuai Zheng , Chen Xu , Changsheng Dong , Bin Pan , Xueshuo Xie , Along He , Tao Li , Huazhu Fu

Diffusion models have shown remarkable empirical success in sampling from rich multi-modal distributions. Their inference relies on numerically solving a certain differential equation. This differential equation cannot be solved in closed…

Machine Learning · Computer Science 2026-01-16 Khashayar Gatmiry , Sitan Chen , Adil Salim

As a class of generative artificial intelligence frameworks inspired by statistical physics, diffusion models have shown extraordinary performance in synthesizing complicated data distributions through a denoising process gradually guided…

Machine Learning · Computer Science 2026-04-23 Fangjun Hu , Guangkuo Liu , Yifan F. Zhang , Xun Gao

Estimating the 6D object pose from a single RGB image often involves noise and indeterminacy due to challenges such as occlusions and cluttered backgrounds. Meanwhile, diffusion models have shown appealing performance in generating…

Computer Vision and Pattern Recognition · Computer Science 2024-03-25 Li Xu , Haoxuan Qu , Yujun Cai , Jun Liu

Diffusion generative models have excelled at diverse image generation and reconstruction tasks across fields. A less explored avenue is their application to discriminative tasks involving regression or classification problems. The…

Cosmology and Nongalactic Astrophysics · Physics 2025-02-26 Nayantara Mudur , Carolina Cuesta-Lazaro , Douglas P. Finkbeiner

Generating realistic motions for digital humans is a core but challenging part of computer animations and games, as human motions are both diverse in content and rich in styles. While the latest deep learning approaches have made…

Computer Vision and Pattern Recognition · Computer Science 2022-12-19 Ziyi Chang , Edmund J. C. Findlay , Haozheng Zhang , Hubert P. H. Shum

We propose DiffusionDet, a new framework that formulates object detection as a denoising diffusion process from noisy boxes to object boxes. During the training stage, object boxes diffuse from ground-truth boxes to random distribution, and…

Computer Vision and Pattern Recognition · Computer Science 2023-08-22 Shoufa Chen , Peize Sun , Yibing Song , Ping Luo