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Integer linear programming (ILP) is an elegant approach to solve linear optimization problems, naturally described using integer decision variables. Within the context of physics-inspired machine learning applied to chemistry, we…

In the last few decades, Machine Learning (ML) has achieved significant success across domains ranging from healthcare, sustainability, and the social sciences, to criminal justice and finance. But its deployment in increasingly…

Machine Learning · Computer Science 2025-09-03 Nathan Justin , Qingshi Sun , Andrés Gómez , Phebe Vayanos

Solutions to the Algorithm Selection Problem (ASP) in machine learning face the challenge of high computational costs associated with evaluating various algorithms' performances on a given dataset. To mitigate this cost, the meta-learning…

Machine Learning · Computer Science 2025-09-12 Cynthia Moreira Maia , Lucas B. V. de Amorim , George D. C. Cavalcanti , Rafael M. O. Cruz

SMLP: Symbolic Machine Learning Prover an open source tool for exploration and optimization of systems represented by machine learning models. SMLP uses symbolic reasoning for ML model exploration and optimization under verification and…

Machine Learning · Computer Science 2024-05-17 Franz Brauße , Zurab Khasidashvili , Konstantin Korovin

The idea of using machine learning (ML) methods to reconstruct the dynamics of a system is the topic of recent studies in the geosciences, in which the key output is a surrogate model meant to emulate the dynamical model. In order to treat…

Machine Learning · Statistics 2021-09-22 Alban Farchi , Patrick Laloyaux , Massimo Bonavita , Marc Bocquet

Background: Coevolution within a protein family is often predicted using statistics that measure the degree of covariation between positions in the protein sequence. Mutual Information is a measure of dependence between two random variables…

Populations and Evolution · Quantitative Biology 2013-04-17 Russell J. Dickson , Gregory B. Gloor

Model-based optimization approaches for monitoring and control, such as model predictive control and optimal state and parameter estimation, have been used for decades in many engineering applications. Models describing the dynamics,…

Systems and Control · Electrical Eng. & Systems 2022-03-31 Johannes Pohlodek , Bruno Morabito , Christian Schlauch , Pablo Zometa , Rolf Findeisen

Mixed-Integer Linear Programming (MILP) is a cornerstone of combinatorial optimization, yet solving large-scale instances remains a significant computational challenge. Recently, Graph Neural Networks (GNNs) have shown promise in…

Machine Learning · Computer Science 2025-11-13 Tianle Pu , Jianing Li , Yingying Gao , Shixuan Liu , Zijie Geng , Haoyang Liu , Chao Chen , Changjun Fan

Uncertainty in optimization is often represented as stochastic parameters in the optimization model. In Predict-Then-Optimize approaches, predictions of a machine learning model are used as values for such parameters, effectively…

Machine Learning · Computer Science 2025-12-03 Pieter Smet

Efficient algorithms and solvers are required to provide optimal or near-optimal solutions quickly and enable organizations to react promptly to dynamic situations such as supply chain disruptions or changing customer demands.…

Optimization and Control · Mathematics 2024-09-10 Charly Robinson La Rocca , Jean-François Cordeau , Emma Frejinger

The Multi-Objective Mixed-Integer Programming (MOMIP) problem is one of the most challenging. To derive its Pareto optimal solutions one can use the well-known Chebyshev scalarization and Mixed-Integer Programming (MIP) solvers. However,…

Optimization and Control · Mathematics 2024-01-02 Grzegorz Filcek , Janusz Miroforidis

In this paper, we describe a novel unsupervised learning scheme for accelerating the solution of a family of mixed integer programming (MIP) problems. Distinct substantially from existing learning-to-optimize methods, our proposal seeks to…

Optimization and Control · Mathematics 2024-12-25 Shiyuan Qu , Fenglian Dong , Zhiwei Wei , Chao Shang

Finding optimal join orders is among the most crucial steps to be performed by query optimisers. Though extensively studied in data management research, the problem remains far from solved: While query optimisers rely on exhaustive search…

Databases · Computer Science 2025-10-24 Manuel Schönberger , Immanuel Trummer , Wolfgang Mauerer

In this paper, we develop a new formulation of changeover constraints for mixed integer programming problem (MIP) that emerges in solving a short-term production scheduling problem. The new model requires fewer constraints than the original…

Optimization and Control · Mathematics 2014-08-28 Pavel A. Borisovsky , Anton V. Eremeev , Josef Kallrath

The state-of-the-art in optimal control from timed temporal logic specifications, including Metric Temporal Logic (MTL) and Signal Temporal Logic (STL), is based on Mixed-Integer Convex Programming (MICP). The standard MICP approach is…

Systems and Control · Electrical Eng. & Systems 2021-12-03 Vince Kurtz , Hai Lin

Mixed-integer linear programming (MILP) plays a crucial role in artificial intelligence, biochemistry, finance, cryptography, etc. Notwithstanding popular for decades, the researches of MILP solvers are still limited by the resource…

Quantum Physics · Physics 2022-04-12 Hao Wang , Yu Pan , Wei Cui

Mixed-integer rounding (MIR) cutting planes (cuts) are effective at improving the strength of a linear relaxation for mixed-integer linear programming (MIP) problems. The cuts in this family are derived by aggregating constraints then…

Optimization and Control · Mathematics 2024-12-16 Oscar Guaje , Arnaud Deza , Aleksandr M. Kazachkov , Elias B. Khalil

This paper addresses a mixed integer programming (MIP) formulation for the multi-item uncapacitated lot-sizing problem that is inspired from the trailer manufacturer. The proposed MIP model has been utilized to find out the optimum order…

Optimization and Control · Mathematics 2012-06-01 Maryam Mohammadi , Masine Md. Tap

Constraint Programming (CP) users need significant expertise in order to model their problems appropriately, notably to select propagators and search strategies. This puts the brakes on a broader uptake of CP. In this paper, we introduce…

Artificial Intelligence · Computer Science 2016-11-29 Thierry Petit

Mixed-Integer Linear Programming (MILP) plays an important role across a range of scientific disciplines and within areas of strategic importance to society. The MILP problems, however, suffer from combinatorial complexity. Because of…

Optimization and Control · Mathematics 2023-01-06 Mikhail A. Bragin , Emily L. Tucker
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