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Contrastive learning is a powerful self-supervised learning method, but we have a limited theoretical understanding of how it works and why it works. In this paper, we prove that contrastive learning with the standard InfoNCE loss is…

Machine Learning · Computer Science 2024-02-26 Zhiquan Tan , Yifan Zhang , Jingqin Yang , Yang Yuan

In high-stakes medical applications, consistent answering across diverse question phrasings is essential for reliable diagnosis. However, we reveal that current Medical Vision-Language Models (Med-VLMs) exhibit concerning fragility in…

Computation and Language · Computer Science 2025-08-27 Songtao Jiang , Yuxi Chen , Sibo Song , Yan Zhang , Yeying Jin , Yang Feng , Jian Wu , Zuozhu Liu

Background: Clinical guidelines and recommendations are the driving wheels of the evidence-based medicine (EBM) paradigm, but these are available primarily as unstructured text and are generally highly heterogeneous in nature. This…

Computation and Language · Computer Science 2016-09-07 Ravi P Garg , Kalpana Raja , Siddhartha R Jonnalagadda

We address the fundamental task of inferring cross-document coreference and hierarchy in scientific texts, which has important applications in knowledge graph construction, search, recommendation and discovery. Large Language Models (LLMs)…

Computation and Language · Computer Science 2026-02-04 Lior Forer , Tom Hope

Answering complex real-world questions in the medical domain often requires accurate retrieval from medical Textual Knowledge Graphs (medical TKGs), as the relational path information from TKGs could enhance the inference ability of Large…

Computation and Language · Computer Science 2026-04-14 Jiatan Huang , Mingchen Li , Zonghai Yao , Dawei Li , Yuxin Zhang , Zhichao Yang , Yongkang Xiao , Feiyun Ouyang , Xiaohan Li , Shuo Han , Hong Yu

There is enormous enthusiasm and concerns in using large language models (LLMs) in healthcare, yet current assumptions are all based on general-purpose LLMs such as ChatGPT. This study develops a clinical generative LLM, GatorTronGPT, using…

Retrieval-augmented generation (RAG) grounds large language models in external medical knowledge, yet standard retrievers frequently surface hard negatives that are semantically close to the query but describe clinically distinct…

Information Retrieval · Computer Science 2026-04-07 Byeolhee Kim , Min-Kyung Kim , Young-Hak Kim , Tae-Joon Jeon

Lyrics alignment gained considerable attention in recent years. State-of-the-art systems either re-use established speech recognition toolkits, or design end-to-end solutions involving a Connectionist Temporal Classification (CTC) loss.…

Sound · Computer Science 2023-06-14 Simon Durand , Daniel Stoller , Sebastian Ewert

Europe's healthcare systems require enhanced interoperability and digitalization, driving a demand for innovative solutions to process legacy clinical data. This paper presents the results of our project, which aims to leverage Large…

Computation and Language · Computer Science 2025-07-09 Aynur Guluzade , Naguib Heiba , Zeyd Boukhers , Florim Hamiti , Jahid Hasan Polash , Yehya Mohamad , Carlos A Velasco

An energy-based model (EBM) is a popular generative framework that offers both explicit density and architectural flexibility, but training them is difficult since it is often unstable and time-consuming. In recent years, various training…

Machine Learning · Computer Science 2023-03-07 Hankook Lee , Jongheon Jeong , Sejun Park , Jinwoo Shin

Vision-language models pre-trained on large scale of unlabeled biomedical images and associated reports learn generalizable semantic representations. These multi-modal representations can benefit various downstream tasks in the biomedical…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Xinliu Zhong , Kayhan Batmanghelich , Li Sun

Semantic search is an important task which objective is to find the relevant index from a database for query. It requires a retrieval model that can properly learn the semantics of sentences. Transformer-based models are widely used as…

Machine Learning · Computer Science 2022-09-28 Mingxi Tan , Alexis Rolland , Andong Tian

The accelerated adoption of digital pathology and advances in deep learning have enabled the development of powerful models for various pathology tasks across a diverse array of diseases and patient cohorts. However, model training is often…

Clinical trial matching is the task of identifying trials for which patients may be potentially eligible. Typically, this task is labor-intensive and requires detailed verification of patient electronic health records (EHRs) against the…

A key component of deep learning (DL) for natural language processing (NLP) is word embeddings. Word embeddings that effectively capture the meaning and context of the word that they represent can significantly improve the performance of…

Precision medicine fundamentally aims to establish causality between dysregulated biochemical mechanisms and cancer subtypes. Omics-based cancer subtyping has emerged as a revolutionary approach, as different level of omics records the…

Genomics · Quantitative Biology 2023-08-25 Ziwei Yang , Zheng Chen , Yasuko Matsubara , Yasushi Sakurai

Large Language Models (LLMs), particularly those similar to ChatGPT, have significantly influenced the field of Natural Language Processing (NLP). While these models excel in general language tasks, their performance in domain-specific…

Computation and Language · Computer Science 2024-01-02 Omid Rohanian , Mohammadmahdi Nouriborji , David A. Clifton

Pre-trained Language Models (PLMs) have shown superior performance on various downstream Natural Language Processing (NLP) tasks. However, conventional pre-training objectives do not explicitly model relational facts in text, which are…

Computation and Language · Computer Science 2021-05-27 Yujia Qin , Yankai Lin , Ryuichi Takanobu , Zhiyuan Liu , Peng Li , Heng Ji , Minlie Huang , Maosong Sun , Jie Zhou

Recent advances in image-text pretraining have significantly enhanced visual understanding by aligning visual and textual representations. Contrastive Language-Image Pretraining (CLIP) has played a pivotal role in multimodal learning.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-20 Zihan Li , Yiqing Wang , Sina Farsiu , Paul Kinahan

Learning knowledge representation is an increasingly important technology applicable in many domain-specific machine learning problems. We discuss the effectiveness of traditional Link Prediction or Knowledge Graph Completion evaluation…

Artificial Intelligence · Computer Science 2020-02-24 Jianyu Liu , Hegler Tissot