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Pathology has played a crucial role in the diagnosis and evaluation of patient tissue samples obtained from surgeries and biopsies for many years. The advent of Whole Slide Scanners and the development of deep learning technologies have…

Computer Vision and Pattern Recognition · Computer Science 2024-08-07 Mieko Ochi , Daisuke Komura , Shumpei Ishikawa

General-purpose vision-language models demonstrate strong performance in everyday domains but struggle with specialized technical fields requiring precise terminology, structured reasoning, and adherence to engineering standards. This work…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Blessing Agyei Kyem , Joshua Kofi Asamoah , Anthony Dontoh , Armstrong Aboah

Automated generation of diagnostic pathology reports directly from whole slide images (WSIs) is an emerging direction in computational pathology. Translating high-resolution tissue patterns into clinically coherent text remains difficult…

Computer Vision and Pattern Recognition · Computer Science 2025-12-16 Noorul Wahab , Nasir Rajpoot

Diagnosing and treating skin diseases require advanced visual skills across domains and the ability to synthesize information from multiple imaging modalities. While current deep learning models excel at specific tasks like skin cancer…

Advances in digitizing tissue slides and the fast-paced progress in artificial intelligence, including deep learning, have boosted the field of computational pathology. This field holds tremendous potential to automate clinical diagnosis,…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Andrew H. Song , Guillaume Jaume , Drew F. K. Williamson , Ming Y. Lu , Anurag Vaidya , Tiffany R. Miller , Faisal Mahmood

This study presents DiagCoT, a multi-stage framework that applies supervised fine-tuning to general-purpose vision-language models (VLMs) to emulate radiologists' stepwise diagnostic reasoning using only free-text reports. DiagCoT combines…

Artificial Intelligence · Computer Science 2025-09-09 Yihong Luo , Wenwu He , Zhuo-Xu Cui , Dong Liang

Artificial intelligence has started to transform histopathology impacting clinical diagnostics and biomedical research. However, while many computational pathology approaches have been proposed, most current AI models are limited with…

The combination of data analysis methods, increasing computing capacity, and improved sensors enable quantitative granular, multi-scale, cell-based analyses. We describe the rich set of application challenges related to tissue…

Artificial Intelligence · Computer Science 2022-06-16 Rajarsi Gupta , Jakub Kaczmarzyk , Soma Kobayashi , Tahsin Kurc , Joel Saltz

We introduce PathGAN, a deep neural network for visual scanpath prediction trained on adversarial examples. A visual scanpath is defined as the sequence of fixation points over an image defined by a human observer with its gaze. PathGAN is…

Computer Vision and Pattern Recognition · Computer Science 2018-09-05 Marc Assens , Xavier Giro-i-Nieto , Kevin McGuinness , Noel E. O'Connor

Visual impairment represents a major global health challenge, with multimodal imaging providing complementary information that is essential for accurate ophthalmic diagnosis. This comprehensive survey systematically reviews the latest…

Image and Video Processing · Electrical Eng. & Systems 2025-08-07 Xiaoling Luo , Ruli Zheng , Qiaojian Zheng , Zibo Du , Shuo Yang , Meidan Ding , Qihao Xu , Chengliang Liu , Linlin Shen

Medicine is inherently multimodal, with rich data modalities spanning text, imaging, genomics, and more. Generalist biomedical artificial intelligence (AI) systems that flexibly encode, integrate, and interpret this data at scale can…

ChatGPT, the most accessible generative artificial intelligence (AI) tool, offers considerable potential for veterinary medicine, yet a dedicated review of its specific applications is lacking. This review concisely synthesizes the latest…

Computers and Society · Computer Science 2024-05-24 Candice P. Chu

Artificial Intelligence (AI) has great potential to improve health outcomes by training systems on vast digitized clinical datasets. Computational Pathology, with its massive amounts of microscopy image data and impact on diagnostics and…

Image and Video Processing · Electrical Eng. & Systems 2024-05-24 Gabriele Campanella , Eugene Fluder , Jennifer Zeng , Chad Vanderbilt , Thomas J. Fuchs

Vision-language foundation models have shown great promise in computational pathology but remain primarily data-driven, lacking explicit integration of medical knowledge. We introduce KEEP (KnowledgE-Enhanced Pathology), a foundation model…

Image and Video Processing · Electrical Eng. & Systems 2026-01-28 Xiao Zhou , Luoyi Sun , Dexuan He , Wenbin Guan , Ge Wang , Ruifen Wang , Lifeng Wang , Xiaojun Yuan , Xin Sun , Ya Zhang , Kun Sun , Yanfeng Wang , Weidi Xie

Tissue phenotyping is a fundamental computational pathology (CPath) task in learning objective characterizations of histopathologic biomarkers in anatomic pathology. However, whole-slide imaging (WSI) poses a complex computer vision problem…

Vision-language models (VLM) have markedly advanced AI-driven interpretation and reporting of complex medical imaging, such as computed tomography (CT). Yet, existing methods largely relegate clinicians to passive observers of final…

Multimodal large language models (MLLMs) have emerged as powerful tools for computational pathology, offering unprecedented opportunities to integrate pathological images with language context for comprehensive diagnostic analysis. These…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Zhe Xu , Ziyi Liu , Junlin Hou , Jiabo Ma , Cheng Jin , Yihui Wang , Zhixuan Chen , Zhengyu Zhang , Fuxiang Huang , Zhengrui Guo , Fengtao Zhou , Yingxue Xu , Xi Wang , Ronald Cheong Kin Chan , Li Liang , Hao Chen

Multimodal alignment of histopathology encoders with transcriptomic and genomic data has been shown to significantly improve performance in downstream diagnostic tasks. Hematological cytology is unique in that visual single-cell evaluation…

Computer Vision and Pattern Recognition · Computer Science 2026-05-29 Muhammed Furkan Dasdelen , Fatih Ozlugedik , Ilaria Looser , Rao Muhammad Umer , Christian Pohlkamp , Carsten Marr

ChatGPT explores a strategic blueprint of question answering (QA) in delivering medical diagnosis, treatment recommendations, and other healthcare support. This is achieved through the increasing incorporation of medical domain data via…

Computation and Language · Computer Science 2024-01-23 Qing Li , Lei Li , Yu Li

Artificial intelligence (AI) has gained significant attention in healthcare consultation due to its potential to improve clinical workflow and enhance medical communication. However, owing to the complex nature of medical information, large…

Computation and Language · Computer Science 2024-03-05 Xiaolan Chen , Ziwei Zhao , Weiyi Zhang , Pusheng Xu , Le Gao , Mingpu Xu , Yue Wu , Yinwen Li , Danli Shi , Mingguang He
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