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Nanorobots are a promising development in targeted drug delivery and the treatment of neurological disorders, with potential for crossing the blood-brain barrier (BBB). These small devices leverage advancements in nanotechnology and…

Robotics · Computer Science 2024-11-05 Shahab Kavousinejad

Computational methods that operate on three-dimensional molecular structure have the potential to solve important questions in biology and chemistry. In particular, deep neural networks have gained significant attention, but their…

A method is proposed for high-resolution, three-dimensional reconstruction of internal structure of objects from planar transmission images. The described approach can be used with any form of radiation or matter waves, in principle,…

Optics · Physics 2022-08-24 T. E. Gureyev , H. M. Quiney , L. J. Allen

In this work, we develop a novel technique for reconstructing images from projection-based nano- and microtomography. Our contribution focuses on enhancing reconstruction quality, particularly for specimen composed of homogeneous material…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Anuraag Mishra , Andrea Gilch , Benjamin Apeleo Zubiri , Jan Rolfes , Frauke Liers

High-resolution optical imaging methods, such as confocal microscopy and full-field optical coherence tomography, capture flat optical sections of the sample. If the sample is curved, the optical field sections through several sample layers…

Medical Physics · Physics 2020-07-31 Viacheslav Mazlin , Kristina Irsch , Michel Paques , Mathias Fink , Albert Claude Boccara

Proton radiography is a technique extensively used to resolve magnetic field structures in high energy density plasmas, revealing a whole variety of interesting phenomena such as magnetic reconnection and collisionless shocks found in…

Automation holds the potential to assist surgeons in robotic interventions, shifting their mental work load from visuomotor control to high level decision making. Reinforcement learning has shown promising results in learning complex…

In conventional tomographic reconstruction, the pre-processing step includes flat-field correction, where each sample projection on the detector is divided by a reference image taken without the sample. When using coherent X-rays as probe,…

Image and Video Processing · Electrical Eng. & Systems 2024-10-24 Viktor Nikitin , Marcus Carlsson , Doga Gursoy , Rajmund Mokso , Peter Cloetens

Early cancer detection remains one of the most critical challenges in modern healthcare, where delayed diagnosis significantly reduces survival outcomes. Recent advancements in artificial intelligence, particularly deep learning, have…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Emmanuella Avwerosuoghene Oghenekaro

Signal transduction and cell function are governed by the spatiotemporal organization of membrane-associated molecules. Despite significant advances in visualizing molecular distributions by 3D light microscopy, cell biologists still have…

Quantitative Methods · Quantitative Biology 2023-04-14 Felix Y. Zhou , Andrew Weems , Gabriel M. Gihana , Bingying Chen , Bo-Jui Chang , Meghan Driscoll , Gaudenz Danuser

Computational models of cardiac structure and function are increasingly central to the development of subject-specific cardiac digital twins, enabling improved characterization of contractile dysfunction, pathological remodeling, and…

Computed Tomography (CT) reconstruction of objects with cylindrical symmetry can be performed with a single projection. When the measured rays are parallel, and the axis of symmetry is perpendicular to the optical axis, the data can be…

Medical Physics · Physics 2024-10-15 Kyle M. Champley , Ibrahim Oksuz , Matthew G. Bisbee , Joseph W. Tringe , Brian Maddox

The aim of this research review is to propose the logic and search mechanism for the development of an artificially intelligent automaton (AIA) that can find affected cells in a 3-dimensional biological system. Research on the possible…

Computational Engineering, Finance, and Science · Computer Science 2011-07-04 Jitesh Dundas

Optical coherence tomography (OCT) is a micrometer-scale, volumetric imaging modality that has become a clinical standard in ophthalmology. OCT instruments image by raster-scanning a focused light spot across the retina, acquiring…

Image and Video Processing · Electrical Eng. & Systems 2022-09-16 Stefan Ploner , Siyu Chen , Jungeun Won , Lennart Husvogt , Katharina Breininger , Julia Schottenhamml , James Fujimoto , Andreas Maier

Computational Pathology (CPath) is an emerging field concerned with the study of tissue pathology via computational algorithms for the processing and analysis of digitized high-resolution images of tissue slides. Recent deep learning based…

Image and Video Processing · Electrical Eng. & Systems 2021-12-20 Amina Asif , Kashif Rajpoot , David Snead , Fayyaz Minhas , Nasir Rajpoot

Endovascular procedures have revolutionized vascular disease treatment, yet their manual execution is challenged by the demands for high precision, operator fatigue, and radiation exposure. Robotic systems have emerged as transformative…

Mechanical strain and stress play a major role in biological processes such as wound healing or morphogenesis. To assess this role quantitatively, fixed or live images of tissues are acquired at a cellular precision in large fields of…

Tissues and Organs · Quantitative Biology 2019-06-12 M. Durande , S. Tlili , T. Homan , B. Guirao , F. Graner , H. Delanoë-Ayari

In the last decade, researchers working in the domain of computer vision and Artificial Intelligence (AI) have beefed up their efforts to come up with the automated framework that not only detects but also identifies stage of breast cancer.…

Image and Video Processing · Electrical Eng. & Systems 2022-01-10 Shahid Munir Shah , Rizwan Ahmed Khan , Sheeraz Arif , Unaiza Sajid

All-optical image processing offers a high-speed, energy-efficient alternative to conventional electronic systems by leveraging the wave nature of light for parallel computation. However, traditional optical processors rely on bulky…

Optics · Physics 2026-03-17 Linzhi Yu , Haobijam J. Singh , Jesse Pietila , Humeyra Caglayan

Fontan palliation for univentricular congenital heart disease progresses to hemodynamic failure with complex flow patterns poorly characterized by conventional 2D imaging. Current assessment relies on fluoroscopic angiography, providing…

Image and Video Processing · Electrical Eng. & Systems 2025-09-18 Prahlad G Menon