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Related papers: Large Language Models are Clinical Reasoners: Reas…

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Large language models (LLMs) are increasingly being applied to clinical care, a domain where both accuracy and transparent reasoning are critical for safe and trustworthy deployment. Chain-of-thought (CoT) prompting, which elicits…

Computation and Language · Computer Science 2025-12-09 Jiageng Wu , Kevin Xie , Bowen Gu , Nils Krüger , Kueiyu Joshua Lin , Jie Yang

Reasoning Large Language Models (LLMs) with enhanced accuracy and explainability are increasingly being adopted in the medical domain, as the life-critical nature of clinical decision-making demands reliable support. Despite these…

Computation and Language · Computer Science 2025-11-12 Sung-Min Lee , Siyoon Lee , Juyeon Kim , Kyoungmin Roh

Recent advancements in reasoning-enhanced large language models (LLMs), such as DeepSeek-R1 and OpenAI-o3, have demonstrated significant progress. However, their application in professional medical contexts remains underexplored,…

Computation and Language · Computer Science 2025-03-11 Pengcheng Qiu , Chaoyi Wu , Shuyu Liu , Weike Zhao , Zhuoxia Chen , Hongfei Gu , Chuanjin Peng , Ya Zhang , Yanfeng Wang , Weidi Xie

Healthcare systems around the world are grappling with issues like inefficient diagnostics, rising costs, and limited access to specialists. These problems often lead to delays in treatment and poor health outcomes. Most current AI and deep…

Artificial Intelligence · Computer Science 2025-12-22 Maliha Tabassum , M Shamim Kaiser

Numerous decision-making tasks require estimating causal effects under interventions on different parts of a system. As practitioners consider using large language models (LLMs) to automate decisions, studying their causal reasoning…

Machine Learning · Computer Science 2024-12-24 Tejas Kasetty , Divyat Mahajan , Gintare Karolina Dziugaite , Alexandre Drouin , Dhanya Sridhar

The differential diagnosis of neurodegenerative dementias is a challenging clinical task, mainly because of the overlap in symptom presentation and the similarity of patterns observed in structural neuroimaging. To improve diagnostic…

Machine Learning · Computer Science 2025-05-27 Andrew Zamai , Nathanael Fijalkow , Boris Mansencal , Laurent Simon , Eloi Navet , Pierrick Coupe

To perform effective causal inference in high-dimensional datasets, initiating the process with causal discovery is imperative, wherein a causal graph is generated based on observational data. However, obtaining a complete and accurate…

Machine Learning · Computer Science 2025-04-18 Elahe Khatibi , Mahyar Abbasian , Zhongqi Yang , Iman Azimi , Amir M. Rahmani

Large language models (LLMs) have dramatically enhanced the field of language intelligence, as demonstrably evidenced by their formidable empirical performance across a spectrum of complex reasoning tasks. Additionally, theoretical proofs…

Computation and Language · Computer Science 2023-11-21 Zhuosheng Zhang , Yao Yao , Aston Zhang , Xiangru Tang , Xinbei Ma , Zhiwei He , Yiming Wang , Mark Gerstein , Rui Wang , Gongshen Liu , Hai Zhao

Large reasoning models (LRMs) achieve strong performance on mathematical reasoning tasks, often attributed to their capability to generate explicit chain-of-thought (CoT) explanations. However, recent work shows that LRMs often arrive at…

Computation and Language · Computer Science 2026-04-20 Yihong Liu , Raoyuan Zhao , Hinrich Schütze , Michael A. Hedderich

Large Language Models (LLMs) have shown impressive performance on complex tasks through Chain-of-Thought (CoT) reasoning. However, conventional CoT relies on explicitly verbalized intermediate steps, which constrains its broader…

Computation and Language · Computer Science 2025-11-04 Xinghao Chen , Anhao Zhao , Heming Xia , Xuan Lu , Hanlin Wang , Yanjun Chen , Wei Zhang , Jian Wang , Wenjie Li , Xiaoyu Shen

The diagnosis of most mental disorders, including psychiatric evaluations, primarily depends on dialogues between psychiatrists and patients. This subjective process can lead to variability in diagnoses across clinicians and patients,…

Artificial Intelligence · Computer Science 2025-10-30 Eranga Bandara , Ross Gore , Atmaram Yarlagadda , Anita H. Clayton , Preston Samuel , Christopher K. Rhea , Sachin Shetty

Large language models (LLMs) show promise for diagnostic reasoning but often lack reliable, knowledge grounded inference. Knowledge graphs (KGs), such as the Unified Medical Language System (UMLS), offer structured biomedical knowledge that…

Computation and Language · Computer Science 2025-09-24 Saksham Khatwani , He Cheng , Majid Afshar , Dmitriy Dligach , Yanjun Gao

Clinical diagnosis is a complex reasoning process in which clinicians gather evidence, form hypotheses, and test them against alternative explanations. In medical training, this reasoning is explicitly developed through counterfactual…

Computation and Language · Computer Science 2026-04-24 Zhiwen You , Xi Chen , Aniket Vashishtha , Simo Du , Gabriel Erion-Barner , Hongyuan Mei , Hao Peng , Yue Guo

Language has long been conceived as an essential tool for human reasoning. The breakthrough of Large Language Models (LLMs) has sparked significant research interest in leveraging these models to tackle complex reasoning tasks. Researchers…

Large language models (LLMs) excel on many NLP benchmarks, but their behavior on real-world, semi-structured prediction remains underexplored. We present LlaMADRS, a benchmark for structured clinical assessment from dialogue built on the…

Human-Computer Interaction · Computer Science 2026-04-23 Gaoussou Youssouf Kebe , Jeffrey M. Girard , Einat Liebenthal , Justin Baker , Fernando De la Torre , Louis-Philippe Morency

Mathematical reasoning has long represented one of the most fundamental and challenging frontiers in artificial intelligence research. In recent years, large language models (LLMs) have achieved significant advances in this area. This…

Artificial Intelligence · Computer Science 2025-06-11 Peng-Yuan Wang , Tian-Shuo Liu , Chenyang Wang , Yi-Di Wang , Shu Yan , Cheng-Xing Jia , Xu-Hui Liu , Xin-Wei Chen , Jia-Cheng Xu , Ziniu Li , Yang Yu

As a cornerstone of patient care, clinical decision-making significantly influences patient outcomes and can be enhanced by large language models (LLMs). Although LLMs have demonstrated remarkable performance, their application to visual…

Computer Vision and Pattern Recognition · Computer Science 2025-06-16 Ji Young Byun , Young-Jin Park , Navid Azizan , Rama Chellappa

Large language models (LLMs) have recently shown remarkable performance in language tasks and beyond. However, due to their limited inherent causal reasoning ability, LLMs still face challenges in handling tasks that require robust causal…

Computation and Language · Computer Science 2025-03-13 Xin Li , Zhuo Cai , Shoujin Wang , Kun Yu , Fang Chen

Recent works on large language models (LLMs) have demonstrated the impact of prompting strategies and fine-tuning techniques on their reasoning capabilities. Yet, their effectiveness on clinical natural language inference (NLI) remains…

Computation and Language · Computer Science 2025-07-08 Mael Jullien , Marco Valentino , Leonardo Ranaldi , Andre Freitas

Chain-of-Thought (CoT) reasoning has proven effective in enhancing large language models by encouraging step-by-step intermediate reasoning, and recent advances have extended this paradigm to Multimodal Large Language Models (MLLMs). In the…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Juntao Jiang , Jiangning Zhang , Yali Bi , Jinsheng Bai , Weixuan Liu , Weiwei Jin , Zhucun Xue , Yong Liu , Xiaobin Hu , Shuicheng Yan